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Gene: Zar1l (zygote arrest 1 like) Chinchilla lanigera

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Symbol:

Zar1l

Name:

zygote arrest 1 like

RGD ID:

8837520

Description:

ENCODES a protein that exhibits mRNA 3'-UTR binding (ortholog); INVOLVED IN negative regulation of translation (ortholog); oocyte maturation (ortholog); ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN cytoplasm (ortholog); intracellular membraneless organelle (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

zygote arrest 1-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZAR1L (zygote arrest 1 like)	NCBI	Ortholog
Mus musculus (house mouse):	Zar1l (zygote arrest 1-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Zar1l (zygote arrest 1-like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZAR1L (zygote arrest 1 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZAR1L (zygote arrest 1 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Zar1l (zygote arrest 1 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZAR1L (zygote arrest 1 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZAR1L (zygote arrest 1 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Zar1l (zygote arrest 1 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955431	13,532,795 - 13,541,682 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955431	13,532,795 - 13,541,771 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary breast ovarian cancer syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of translation (ISO)

oocyte maturation (ISO)

Cellular Component

cytoplasm (ISO)

intracellular membraneless organelle (ISO)

Molecular Function

mRNA 3'-UTR binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Zar1l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955431	13,532,795 - 13,541,682 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955431	13,532,795 - 13,541,771 (+)	NCBI	ChiLan1.0	ChiLan1.0

ZAR1L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	32,303,699 - 32,315,363 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	32,303,699 - 32,315,363 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	32,877,836 - 32,889,500 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	31,775,837 - 31,784,062 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	13	13,944,739 - 13,952,921 (-)	NCBI		Celera
Cytogenetic Map	13	q13.1	NCBI
HuRef	13	13,689,477 - 13,697,879 (-)	NCBI		HuRef
CHM1_1	13	32,845,455 - 32,853,638 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	31,520,944 - 31,532,608 (-)	NCBI		T2T-CHM13v2.0

Zar1l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	150,430,520 - 150,441,659 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	150,430,520 - 150,441,629 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	150,507,055 - 150,518,194 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	150,507,055 - 150,518,164 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	151,309,644 - 151,320,734 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	150,775,434 - 150,786,376 (-)	NCBI		MGSCv36	mm8
Celera	5	148,511,597 - 148,522,685 (-)	NCBI		Celera
Cytogenetic Map	5	G3	NCBI
cM Map	5	89.51	NCBI

Zar1l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	4,882,162 - 4,892,064 (-)	NCBI		GRCr8
mRatBN7.2	12	46,534 - 56,434 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	46,534 - 56,425 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	12	491,043 - 500,372 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	491,007 - 499,601 (-)	NCBI	Rnor6.0		rn6	Rnor6.0
RGSC_v3.4	12	4,323,628 - 4,337,022 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	1,756,183 - 1,766,124 (-)	NCBI		Celera
Cytogenetic Map	12	p12	NCBI

ZAR1L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	31,869,708 - 31,878,687 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	22,976,223 - 22,985,180 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	13,562,691 - 13,571,395 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	31,997,411 - 32,005,724 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	31,997,411 - 32,005,724 (-)	Ensembl	panpan1.1		panPan2

ZAR1L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	7,799,130 - 7,807,653 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	7,799,615 - 7,856,230 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	7,827,909 - 7,917,527 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	7,895,358 - 7,932,137 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	7,895,804 - 7,905,469 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	7,794,791 - 7,883,229 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	7,792,167 - 7,881,786 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	7,850,128 - 7,939,890 (+)	NCBI		UU_Cfam_GSD_1.0

Zar1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	169,009,032 - 169,017,629 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936472	26,934,701 - 26,942,483 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936472	26,934,689 - 26,942,483 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZAR1L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	8,795,487 - 8,805,881 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	8,795,478 - 8,805,876 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ZAR1L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	11,058,794 - 11,069,865 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	11,059,156 - 11,067,146 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666057	33,285,409 - 33,293,985 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zar1l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624776	5,576,656 - 5,586,907 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624776	5,575,367 - 5,586,098 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005387721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01030308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01107744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000007139 ⟹ ENSCLAP00000007027

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955431	13,532,795 - 13,541,682 (+)	Ensembl

RefSeq Acc Id:

XM_005387721 ⟹ XP_005387778

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955431	13,532,795 - 13,541,771 (+)	NCBI

Sequence:

show sequence

ATGGAGCGCTTTGTCCGTGTTCCCTACGTCTGGTACCAGGACTGTCGAAACACACTGCCCATGG
GCCAGTCTCGACTCTCAGGGCATAGTCAGCCCAACTGGAGGCAAAGCATGGGTCCTCCAACTTT
CCTGGCCAGGCCAGGGCTGCTGGTGCCAGCAAATGCCTCCGAGTACTGGATGAACCCTTACAGG
AGGGCCCACTTTGAGCCCATTCTCACCCAGATGAACCCCAATCTGTGCCGACAGCTGTGCAAGG
CCAGCACCAAGGAGGTGGGCATACAGGTGAGCCTGCGGGTGGACAAGTCCATGCAGTGCTCGCT
GGGGCCTCAAACTCTGCACAGCTGCTACCCATGGAACAACGCTGACCACAAGAAACCCGTGACA
GACTGGGGAGTCTATTCGCCATTGATGGGCCGCAGGGGCTTTGCCTGGTTAAGGAAGGATGGGG
AAGATAGCAAAAGCAAGGTGCTTTCAGGCCCAGCGAAGGCCAACCAGCAGCCACCACCAATGCC
AAAGTCAGAAGGCGAAAGGCAGGAGGAACCCCCTCAGTCGCAGGAGGTGGTGGAGGAAGATGCC
AAGCATCTTGGTGAAGGGAAGAGCAAGTGGGTACAAGGAGACGGAGTTGGCGGTCCACTTCAGA
AGCCCAGCTTCCAGTCTTTGGAACCAAAATACGGCTATTTTCACTGTAAAGACTGTAACACCCG
ATGGGAGAGTGCGTATGTGTGGTGCATTTCTGGAACTAACAAGGTTTATTTCAAACAACTCTGT
TCCAAATGCCAAAAGAGTTTTAACCCTTACCGAGTAGAAGCAATCCAATGTCAGACCTGTTCAA
AGTCTCAATGTTCCTGTCCTGAAAAGAAAAGACATAATGATAGAAGGAGGCCTCATCGGCAAGA
GCTGTGTGGTCGCTGCAAAGACAAGAAATTCTCCTGTGGCAATATTTATAATTCTAAGTATATC
GTGTGACCAGCCGTGTGGTTTGTGAACTCTTATGCTTTACTGTCATTTACTTTTTCACATCTTA
CCGCTGACGTGGCATTGCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005387778	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000007027.1

RefSeq Acc Id:

XP_005387778 ⟸ XM_005387721

- UniProtKB:

A0A8C2V244 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MERFVRVPYVWYQDCRNTLPMGQSRLSGHSQPNWRQSMGPPTFLARPGLLVPANASEYWMNPYR
RAHFEPILTQMNPNLCRQLCKASTKEVGIQVSLRVDKSMQCSLGPQTLHSCYPWNNADHKKPVT
DWGVYSPLMGRRGFAWLRKDGEDSKSKVLSGPAKANQQPPPMPKSEGERQEEPPQSQEVVEEDA
KHLGEGKSKWVQGDGVGGPLQKPSFQSLEPKYGYFHCKDCNTRWESAYVWCISGTNKVYFKQLC
SKCQKSFNPYRVEAIQCQTCSKSQCSCPEKKRHNDRRRPHRQELCGRCKDKKFSCGNIYNSKYI
V

hide sequence

Ensembl Acc Id:

ENSCLAP00000007027 ⟸ ENSCLAT00000007139

Protein Domains

3CxxC-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000004947	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000007139.1	UniProtKB/TrEMBL
InterPro	Zar1	UniProtKB/TrEMBL
	Znf-3CxxC	UniProtKB/TrEMBL
NCBI Gene	Zar1l	ENTREZGENE
PANTHER	PTHR31054	UniProtKB/TrEMBL
	ZAR1-LIKE PROTEIN	UniProtKB/TrEMBL
Pfam	zf-3CxxC	UniProtKB/TrEMBL
SMART	zf-3CxxC	UniProtKB/TrEMBL
UniProt	A0A8C2V244	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-02-28	Zar1l	zygote arrest 1 like		zygote arrest 1-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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