Ca4 (carbonic anhydrase 4) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ca4 (carbonic anhydrase 4) Chinchilla lanigera
Analyze
Symbol: Ca4
Name: carbonic anhydrase 4
RGD ID: 8835247
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); INVOLVED IN bicarbonate transport (ortholog); response to steroid hormone (ortholog); response to xenobiotic stimulus (ortholog); ASSOCIATED WITH Colonic Neoplasms (ortholog); fundus dystrophy (ortholog); genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); brush border membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: carbonic anhydrase IV
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554511,486,010 - 1,494,084 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554511,485,939 - 1,493,249 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ca4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554511,486,010 - 1,494,084 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554511,485,939 - 1,493,249 (+)NCBIChiLan1.0ChiLan1.0
CA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381760,149,973 - 60,179,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1760,149,942 - 60,170,899 (+)EnsemblGRCh38hg38GRCh38
GRCh371758,227,334 - 58,256,382 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,582,131 - 55,591,686 (+)NCBINCBI36Build 36hg18NCBI36
Build 341755,582,130 - 55,591,686NCBI
Celera1754,687,198 - 54,696,791 (+)NCBICelera
Cytogenetic Map17q23.1NCBI
HuRef1753,598,240 - 53,607,844 (+)NCBIHuRef
CHM1_11758,291,334 - 58,300,936 (+)NCBICHM1_1
T2T-CHM13v2.01761,018,933 - 61,047,969 (+)NCBIT2T-CHM13v2.0
Car4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,848,580 - 84,856,880 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1184,848,612 - 84,856,870 (+)EnsemblGRCm39 Ensembl
GRCm381184,957,754 - 84,966,054 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,957,786 - 84,966,044 (+)EnsemblGRCm38mm10GRCm38
MGSCv371184,771,256 - 84,779,556 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361184,774,038 - 84,782,239 (+)NCBIMGSCv36mm8
Celera1194,577,982 - 94,586,281 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.34NCBI
Car4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81070,325,102 - 70,333,916 (+)NCBIGRCr8
mRatBN7.21069,827,945 - 69,836,501 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1069,827,945 - 69,836,501 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1074,447,929 - 74,456,487 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01073,952,696 - 73,961,254 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01069,417,368 - 69,425,928 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01072,272,286 - 72,281,069 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1072,272,248 - 72,281,067 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01072,173,022 - 72,188,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41073,229,211 - 73,237,707 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11073,243,580 - 73,252,077 (+)NCBI
Celera1068,755,736 - 68,764,294 (+)NCBICelera
Cytogenetic Map10q26NCBI
CA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21976,333,203 - 76,361,305 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11781,143,962 - 81,166,490 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01754,236,114 - 54,258,638 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
CA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1936,327,919 - 36,337,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl936,327,969 - 36,337,088 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha935,555,114 - 35,563,663 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0937,140,849 - 37,149,372 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl937,140,894 - 37,150,309 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1935,919,574 - 35,928,095 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0936,206,744 - 36,215,265 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0936,294,940 - 36,303,505 (-)NCBIUU_Cfam_GSD_1.0
Ca4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560235,301,294 - 35,310,173 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364901,764,795 - 1,774,645 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364901,764,845 - 1,773,752 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1237,962,943 - 37,972,509 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11237,962,951 - 37,972,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21239,632,792 - 39,642,290 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11631,369,238 - 31,379,366 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660772,113,971 - 2,123,779 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ca4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248713,461,052 - 3,469,838 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248713,462,577 - 3,469,978 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000022000   ⟹   ENSCLAP00000021797
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554511,486,010 - 1,494,084 (+)Ensembl
RefSeq Acc Id: XM_005393960   ⟹   XP_005394017
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554511,485,939 - 1,493,249 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005394017 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021797
  ENSCLAP00000021797.1
RefSeq Acc Id: XP_005394017   ⟸   XM_005393960
- UniProtKB: A0A8C2YTB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000021797   ⟸   ENSCLAT00000022000
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014926 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022000 ENTREZGENE
  ENSCLAT00000022000.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
NCBI Gene LOC102006970 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF95 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt A0A8C2YTB8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ca4  carbonic anhydrase 4    carbonic anhydrase IV  Symbol and/or name change 5135510 APPROVED
2015-08-25 Ca4  carbonic anhydrase IV  LOC102006970  carbonic anhydrase 4-like  Symbol and/or name change 5135510 APPROVED