Sufu (SUFU negative regulator of hedgehog signaling) - Rat Genome Database

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Gene: Sufu (SUFU negative regulator of hedgehog signaling) Chinchilla lanigera
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Symbol: Sufu
Name: SUFU negative regulator of hedgehog signaling
RGD ID: 8834662
Description: ENCODES a protein that exhibits beta-catenin binding (ortholog); protein kinase binding (ortholog); INVOLVED IN aorta development (ortholog); coronary vasculature development (ortholog); cytoplasmic sequestering of transcription factor (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH B-lymphoblastic leukemia/lymphoma (ortholog); basal cell carcinoma (ortholog); brain glioblastoma multiforme (ortholog); FOUND IN cilium (ortholog); cytoplasm (ortholog); GLI-SUFU complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: suppressor of fused homolog; suppressor of fused homolog (Drosophila)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554857,808,131 - 7,925,677 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554857,805,244 - 7,925,414 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Sufu
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554857,808,131 - 7,925,677 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554857,805,244 - 7,925,414 (-)NCBIChiLan1.0ChiLan1.0
SUFU
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10102,503,972 - 102,633,535 (+)EnsemblGRCh38hg38GRCh38
GRCh3810102,502,801 - 102,633,535 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710104,263,729 - 104,393,292 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610104,253,754 - 104,383,199 (+)NCBINCBI36hg18NCBI36
Build 3410104,253,753 - 104,383,199NCBI
Celera1098,004,628 - 98,134,149 (+)NCBI
Cytogenetic Map10q24.32NCBI
HuRef1097,897,496 - 98,026,978 (+)NCBIHuRef
CHM1_110104,547,179 - 104,677,032 (+)NCBICHM1_1
Sufu
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391946,385,335 - 46,477,243 (+)NCBIGRCm39mm39
GRCm39 Ensembl1946,385,335 - 46,477,243 (+)Ensembl
GRCm381946,396,896 - 46,488,804 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1946,396,896 - 46,488,804 (+)EnsemblGRCm38mm10GRCm38
MGSCv371946,471,408 - 46,561,150 (+)NCBIGRCm37mm9NCBIm37
MGSCv361946,450,229 - 46,539,971 (+)NCBImm8
Celera1947,160,488 - 47,250,442 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.85NCBI
Sufu
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21245,257,725 - 245,355,576 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1245,257,768 - 245,355,577 (+)Ensembl
Rnor_6.01266,143,766 - 266,241,742 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,143,818 - 266,239,016 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01273,574,697 - 273,672,663 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,612,377 - 251,708,109 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1241,040,495 - 241,135,358 (+)NCBICelera
Cytogenetic Map1q54NCBI
SUFU
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110102,571,886 - 102,696,472 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10102,571,886 - 102,696,472 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01099,107,516 - 99,231,761 (+)NCBIMhudiblu_PPA_v0panPan3
SUFU
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12814,992,989 - 15,115,499 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2814,992,618 - 15,112,389 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2815,165,295 - 15,287,811 (+)NCBI
ROS_Cfam_1.02815,467,025 - 15,589,735 (+)NCBI
ROS_Cfam_1.0 Ensembl2815,466,996 - 15,589,728 (+)Ensembl
UMICH_Zoey_3.12815,011,961 - 15,134,129 (+)NCBI
UNSW_CanFamBas_1.02815,051,335 - 15,173,877 (+)NCBI
UU_Cfam_GSD_1.02815,183,706 - 15,305,945 (+)NCBI
Sufu
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721331,665,075 - 31,778,513 (-)NCBI
SpeTri2.0NW_0049366003,270,662 - 3,381,722 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUFU
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14113,500,842 - 113,614,517 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114113,500,001 - 113,628,064 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214123,356,101 - 123,481,988 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SUFU
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1995,532,228 - 95,660,594 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl995,532,242 - 95,657,290 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604856,639,722 - 56,772,532 (+)NCBIVero_WHO_p1.0
Sufu
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248311,882,114 - 2,012,341 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000001726   ⟹   ENSCLAP00000001683
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554857,808,131 - 7,925,412 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001727   ⟹   ENSCLAP00000001684
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554857,819,077 - 7,925,677 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001728   ⟹   ENSCLAP00000001685
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554857,840,160 - 7,925,219 (-)Ensembl
RefSeq Acc Id: XM_005403832   ⟹   XP_005403889
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,808,131 - 7,925,412 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005403833   ⟹   XP_005403890
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,808,131 - 7,925,412 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504037   ⟹   XP_013359491
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,807,201 - 7,925,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504038   ⟹   XP_013359492
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,807,201 - 7,925,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504039   ⟹   XP_013359493
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,808,224 - 7,925,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504041   ⟹   XP_013359495
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,807,201 - 7,925,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504042   ⟹   XP_013359496
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,810,050 - 7,925,414 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504043   ⟹   XP_013359497
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554857,805,244 - 7,925,414 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005403890   ⟸   XM_005403833
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_005403889   ⟸   XM_005403832
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_013359497   ⟸   XM_013504043
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_013359492   ⟸   XM_013504038
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013359491   ⟸   XM_013504037
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013359495   ⟸   XM_013504041
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013359493   ⟸   XM_013504039
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013359496   ⟸   XM_013504042
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000001684   ⟸   ENSCLAT00000001727
RefSeq Acc Id: ENSCLAP00000001683   ⟸   ENSCLAT00000001726
RefSeq Acc Id: ENSCLAP00000001685   ⟸   ENSCLAT00000001728


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001257 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000001683 ENTREZGENE
  ENSCLAP00000001684 ENTREZGENE
Ensembl Transcript ENSCLAT00000001726 ENTREZGENE
  ENSCLAT00000001727 ENTREZGENE
NCBI Gene Sufu ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Sufu  SUFU negative regulator of hedgehog signaling    suppressor of fused homolog (Drosophila)  Symbol and/or name change 5135510 APPROVED