Esrp2 (epithelial splicing regulatory protein 2) - Rat Genome Database

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Gene: Esrp2 (epithelial splicing regulatory protein 2) Chinchilla lanigera
Analyze
Symbol: Esrp2
Name: epithelial splicing regulatory protein 2
RGD ID: 8829884
Description: ENCODES a protein that exhibits mRNA binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); branching involved in salivary gland morphogenesis (ortholog); epithelial cell proliferation (ortholog); ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); cleft lip (ortholog); COVID-19 (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554848,426,453 - 8,433,893 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554848,426,453 - 8,433,902 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Esrp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554848,426,453 - 8,433,893 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554848,426,453 - 8,433,902 (+)NCBIChiLan1.0ChiLan1.0
ESRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381668,229,033 - 68,236,127 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1668,229,033 - 68,238,102 (-)EnsemblGRCh38hg38GRCh38
GRCh371668,262,936 - 68,270,030 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,819,951 - 66,827,637 (-)NCBINCBI36Build 36hg18NCBI36
Celera1652,770,943 - 52,778,629 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1654,135,554 - 54,143,240 (-)NCBIHuRef
CHM1_11669,670,487 - 69,678,173 (-)NCBICHM1_1
T2T-CHM13v2.01674,024,780 - 74,031,874 (-)NCBIT2T-CHM13v2.0
Esrp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,856,658 - 106,863,825 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8106,856,951 - 106,863,606 (-)EnsemblGRCm39 Ensembl
GRCm388106,130,319 - 106,137,193 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8106,130,319 - 106,136,974 (-)EnsemblGRCm38mm10GRCm38
MGSCv378108,655,083 - 108,660,874 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368109,020,312 - 109,026,103 (-)NCBIMGSCv36mm8
Celera8110,358,967 - 110,364,758 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.1NCBI
Esrp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81950,944,401 - 50,951,919 (-)NCBIGRCr8
mRatBN7.21934,034,559 - 34,041,726 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1934,034,559 - 34,041,726 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1940,850,101 - 40,857,268 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01941,503,409 - 41,510,575 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01943,802,557 - 43,809,724 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01938,113,412 - 38,120,578 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1938,113,412 - 38,120,578 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01948,980,165 - 48,987,331 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,981,504 - 35,988,670 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11935,987,974 - 35,993,320 (-)NCBI
Celera1933,461,884 - 33,469,050 (-)NCBICelera
Cytogenetic Map19q12NCBI
ESRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21877,771,042 - 77,781,686 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11683,685,390 - 83,692,965 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01648,603,753 - 48,611,869 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11667,995,763 - 68,005,823 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,995,769 - 68,005,829 (-)Ensemblpanpan1.1panPan2
ESRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,287,330 - 81,297,533 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,287,425 - 81,295,353 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,277,498 - 81,287,674 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0581,722,361 - 81,732,537 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl581,722,436 - 81,728,099 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1581,549,072 - 81,559,248 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0581,231,515 - 81,241,702 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0581,873,036 - 81,883,220 (+)NCBIUU_Cfam_GSD_1.0
Esrp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,024,641 - 41,031,274 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647518,557,840 - 18,564,473 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647518,557,840 - 18,564,461 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,802,651 - 28,812,963 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,804,425 - 28,814,478 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ESRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1559,184,624 - 59,192,842 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl559,186,167 - 59,197,003 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604721,921,459 - 21,930,389 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Esrp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474618,075,742 - 18,085,572 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474618,075,755 - 18,090,011 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000019804   ⟹   ENSCLAP00000019611
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554848,426,453 - 8,433,893 (+)Ensembl
RefSeq Acc Id: XM_005403591   ⟹   XP_005403648
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554848,426,453 - 8,433,902 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005403648 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019611
  ENSCLAP00000019611.1
RefSeq Acc Id: XP_005403648   ⟸   XM_005403591
- UniProtKB: A0A8C2VRL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000019611   ⟸   ENSCLAT00000019804
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013457 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019804 ENTREZGENE
  ENSCLAT00000019804.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene Esrp2 ENTREZGENE
PANTHER EPITHELIAL SPLICING REGULATORY PROTEIN 2 UniProtKB/TrEMBL
  HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF53098 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A8C2VRL2 ENTREZGENE, UniProtKB/TrEMBL