F10 (coagulation factor X) - Rat Genome Database

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Gene: F10 (coagulation factor X) Chinchilla lanigera
Analyze
Symbol: F10
Name: coagulation factor X
RGD ID: 8825740
Description: ENCODES a protein that exhibits phospholipid binding (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN positive regulation of TOR signaling (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH blood coagulation disease (ortholog); breast cancer (ortholog); factor VII deficiency (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404666,165 - 682,538 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955404666,142 - 682,598 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
F10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955404666,165 - 682,538 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955404666,142 - 682,598 (-)NCBIChiLan1.0ChiLan1.0
F10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813113,122,799 - 113,149,529 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13113,122,799 - 113,149,529 (+)EnsemblGRCh38hg38GRCh38
GRCh3713113,777,113 - 113,803,843 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3613112,825,114 - 112,851,844 (+)NCBINCBI36Build 36hg18NCBI36
Build 3413112,825,145 - 112,851,842NCBI
Celera1394,603,103 - 94,629,507 (+)NCBICelera
Cytogenetic Map13q34NCBI
HuRef1394,215,823 - 94,242,228 (+)NCBIHuRef
CHM1_113113,745,235 - 113,771,639 (+)NCBICHM1_1
T2T-CHM13v2.013112,374,457 - 112,401,188 (+)NCBIT2T-CHM13v2.0
F10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39813,087,308 - 13,106,676 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl813,087,308 - 13,106,676 (+)EnsemblGRCm39 Ensembl
GRCm38813,037,308 - 13,056,676 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl813,037,308 - 13,056,676 (+)EnsemblGRCm38mm10GRCm38
MGSCv37813,037,308 - 13,056,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36813,037,344 - 13,055,877 (+)NCBIMGSCv36mm8
Celera813,205,092 - 13,223,990 (+)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map85.73NCBI
F10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81683,170,973 - 83,190,280 (-)NCBIGRCr8
mRatBN7.21676,468,834 - 76,488,141 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1676,468,838 - 76,488,141 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1681,749,382 - 81,768,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01685,201,959 - 85,221,266 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01680,451,223 - 80,470,556 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01681,803,169 - 81,822,476 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1681,803,110 - 81,822,716 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01681,288,536 - 81,307,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41681,327,237 - 81,346,544 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11681,327,502 - 81,346,809 (-)NCBI
Celera1674,274,866 - 74,294,173 (-)NCBICelera
Cytogenetic Map16q12.5NCBI
F10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214114,625,296 - 114,651,858 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113113,310,076 - 113,337,459 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01394,263,202 - 94,289,612 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113113,332,124 - 113,358,660 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13113,332,124 - 113,358,660 (+)Ensemblpanpan1.1panPan2
F10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12260,585,563 - 60,597,027 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2260,571,822 - 60,597,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2260,297,960 - 60,309,413 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02261,211,249 - 61,222,710 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2261,211,250 - 61,222,699 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12260,709,507 - 60,721,052 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02260,711,813 - 60,723,235 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02260,742,888 - 60,754,688 (+)NCBIUU_Cfam_GSD_1.0
F10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945195,449,719 - 195,476,829 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936472475,333 - 502,377 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936472475,851 - 502,341 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
F10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1178,521,598 - 78,538,258 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11178,521,760 - 78,538,256 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21186,197,298 - 86,215,095 (-)NCBISscrofa10.2Sscrofa10.2susScr3
F10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1391,125,097 - 91,154,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl391,124,766 - 91,157,376 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604648,141,434 - 48,190,001 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
F10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624793762,330 - 778,282 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624793762,306 - 777,511 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000005781   ⟹   ENSCLAP00000005680
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955404666,165 - 682,538 (-)Ensembl
RefSeq Acc Id: XM_005373972   ⟹   XP_005374029
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955404666,142 - 682,598 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005374029 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000005680
  ENSCLAP00000005680.1
RefSeq Acc Id: XP_005374029   ⟸   XM_005373972
- UniProtKB: A0A8C2UZR2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000005680   ⟸   ENSCLAT00000005781
Protein Domains
EGF-like   Gla   Peptidase S1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004028 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005781 ENTREZGENE
  ENSCLAT00000005781.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  4.10.740.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro Coagulation_fac-like_Gla_dom UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  GLA-like_dom_SF UniProtKB/TrEMBL
  GLA_domain UniProtKB/TrEMBL
  Pept_S1A_FX UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene F10 ENTREZGENE
PANTHER COAGULATION FACTOR UniProtKB/TrEMBL
  COAGULATION FACTOR X UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  FXa_inhibition UniProtKB/TrEMBL
  Gla UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PIRSF Factor_X UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
  EGFBLOOD UniProtKB/TrEMBL
  GLABLOOD UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GLA_1 UniProtKB/TrEMBL
  GLA_2 UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  GLA UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
  SSF57630 UniProtKB/TrEMBL
UniProt A0A8C2UZR2 ENTREZGENE, UniProtKB/TrEMBL