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Gene: Top2b (DNA topoisomerase II beta) Chinchilla lanigera
Symbol: Top2b
Name: DNA topoisomerase II beta
Description: ENCODES a protein that exhibits ATP binding (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN axonogenesis (ortholog); DNA topological change (ortholog); forebrain development (ortholog); PARTICIPATES IN doxorubicin pharmacodynamics pathway; doxorubicin response pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); myeloid leukemia (ortholog); prostate carcinoma in situ (ortholog); FOUND IN cytosol (ortholog); heterochromatin (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA topoisomerase 2-beta; topoisomerase (DNA) II beta; topoisomerase (DNA) II beta 180kDa
Homo sapiens (human) : TOP2B (DNA topoisomerase II beta)  HGNC  Alliance
Mus musculus (house mouse) : Top2b (topoisomerase (DNA) II beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Top2b (DNA topoisomerase II beta)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TOP2B (DNA topoisomerase II beta)
Canis lupus familiaris (dog) : TOP2B (DNA topoisomerase II beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Top2b (DNA topoisomerase II beta)
Sus scrofa (pig) : TOP2B (DNA topoisomerase II beta)
Chlorocebus sabaeus (African green monkey) : TOP2B (DNA topoisomerase II beta)
Heterocephalus glaber (naked mole-rat) : Top2b (DNA topoisomerase II beta)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0NW_00495543017,457,603 - 17,523,115 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)

References - curated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Top2b
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 8824698
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.