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Gene: Top2b (DNA topoisomerase II beta) Chinchilla lanigera
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Symbol: Top2b
Name: DNA topoisomerase II beta
Description: ENCODES a protein that exhibits ATP binding (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN axonogenesis (ortholog); DNA topological change (ortholog); forebrain development (ortholog); PARTICIPATES IN doxorubicin pharmacodynamics pathway; doxorubicin response pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); myeloid leukemia (ortholog); prostate carcinoma in situ (ortholog); FOUND IN cytosol (ortholog); heterochromatin (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA topoisomerase 2-beta; topoisomerase (DNA) II beta; topoisomerase (DNA) II beta 180kDa
Orthologs:
Homo sapiens (human) : TOP2B (DNA topoisomerase II beta)  HGNC  Alliance
Mus musculus (house mouse) : Top2b (topoisomerase (DNA) II beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Top2b (DNA topoisomerase II beta)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TOP2B (DNA topoisomerase II beta)
Canis lupus familiaris (dog) : TOP2B (DNA topoisomerase II beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Top2b (DNA topoisomerase II beta)
Sus scrofa (pig) : TOP2B (DNA topoisomerase II beta)
Chlorocebus sabaeus (African green monkey) : TOP2B (DNA topoisomerase II beta)
Heterocephalus glaber (naked mole-rat) : Top2b (DNA topoisomerase II beta)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543017,457,603 - 17,523,115 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on Top2b
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 8824698
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.