Foxa2 (forkhead box A2) - Rat Genome Database

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Gene: Foxa2 (forkhead box A2) Chinchilla lanigera
Analyze
Symbol: Foxa2
Name: forkhead box A2
RGD ID: 8823706
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN adult locomotory behavior (ortholog); anatomical structure formation involved in morphogenesis (ortholog); anatomical structure morphogenesis (ortholog); PARTICIPATES IN forkhead class A signaling pathway; Hedgehog signaling pathway; ASSOCIATED WITH Diaphragmatic Hernia (ortholog); Experimental Diabetes Mellitus (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cell junction (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: hepatocyte nuclear factor 3-beta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541529,982,940 - 29,986,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541529,982,940 - 29,987,093 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult locomotory behavior  (ISO)
anatomical structure formation involved in morphogenesis  (ISO)
anatomical structure morphogenesis  (ISO)
anterior/posterior pattern specification  (ISO)
cell development  (ISO)
cell differentiation in hindbrain  (ISO)
cell fate specification  (ISO)
cellular response to cadmium ion  (ISO)
connective tissue development  (ISO)
dopaminergic neuron differentiation  (ISO)
dorsal/ventral neural tube patterning  (ISO)
dorsal/ventral pattern formation  (ISO)
ectoderm formation  (ISO)
endocrine pancreas development  (ISO)
epithelial tube branching involved in lung morphogenesis  (ISO)
in utero embryonic development  (ISO)
lung development  (ISO)
lung epithelial cell differentiation  (ISO)
mesendoderm development  (ISO)
negative regulation of detection of glucose  (ISO)
negative regulation of DNA-binding transcription factor activity  (ISO)
negative regulation of epithelial to mesenchymal transition  (ISO)
negative regulation of glucokinase activity  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of transcription from RNA polymerase II promoter by glucose  (ISO)
neuron fate specification  (ISO)
Notch signaling pathway  (ISO)
pattern specification process  (ISO)
positive regulation of embryonic development  (ISO)
positive regulation of gastrulation  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of smoothened signaling pathway  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription by RNA polymerase III  (ISO)
positive regulation of transcription from RNA polymerase II promoter by glucose  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
primitive streak formation  (ISO)
regulation of blood coagulation  (ISO)
regulation of gene expression  (ISO)
regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
regulation of lipid metabolic process  (ISO)
regulation of steroid metabolic process  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
regulation of transcription, DNA-templated  (ISO)
response to insulin  (ISO)
signal transduction involved in regulation of gene expression  (ISO)
somite rostral/caudal axis specification  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Foxa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541529,982,940 - 29,986,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541529,982,940 - 29,987,093 (-)NCBIChiLan1.0ChiLan1.0
FOXA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2022,580,998 - 22,585,455 (-)EnsemblGRCh38hg38GRCh38
GRCh382022,580,998 - 22,585,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372022,561,636 - 22,566,128 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362022,509,823 - 22,514,102 (-)NCBINCBI36hg18NCBI36
Celera2022,635,086 - 22,639,544 (-)NCBI
Cytogenetic Map20p11.21NCBI
HuRef2022,523,682 - 22,527,950 (-)NCBIHuRef
CHM1_12022,562,253 - 22,566,723 (-)NCBICHM1_1
Foxa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392147,884,797 - 147,888,889 (-)NCBIGRCm39mm39
GRCm39 Ensembl2147,884,797 - 147,888,889 (-)Ensembl
GRCm382148,042,877 - 148,046,969 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2148,042,877 - 148,046,969 (-)EnsemblGRCm38mm10GRCm38
MGSCv372147,868,614 - 147,872,705 (-)NCBIGRCm37mm9NCBIm37
MGSCv362147,734,364 - 147,738,410 (-)NCBImm8
Celera2149,306,403 - 149,310,523 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.38NCBI
Foxa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23135,470,123 - 135,474,326 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl3142,383,278 - 142,387,481 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03142,383,084 - 142,387,493 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03148,793,310 - 148,797,690 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43136,739,009 - 136,743,204 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13136,644,581 - 136,648,777 (-)NCBI
Celera3134,324,023 - 134,328,218 (-)NCBICelera
Cytogenetic Map3q41NCBI
FOXA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12022,872,251 - 22,874,997 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v02022,519,942 - 22,524,262 (-)NCBIMhudiblu_PPA_v0panPan3
FOXA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1241,010,370 - 1,013,791 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl241,010,651 - 1,013,072 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha241,034,459 - 1,038,788 (+)NCBI
ROS_Cfam_1.0241,413,104 - 1,417,432 (+)NCBI
UMICH_Zoey_3.1241,010,961 - 1,015,301 (+)NCBI
UNSW_CanFamBas_1.0241,114,770 - 1,118,263 (+)NCBI
UU_Cfam_GSD_1.0241,388,439 - 1,392,767 (+)NCBI
Foxa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640149,544,748 - 149,549,068 (+)NCBI
SpeTri2.0NW_0049366202,966,341 - 2,969,349 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1729,997,400 - 30,001,707 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11729,997,397 - 30,001,704 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21734,053,453 - 34,057,746 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FOXA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1251,577,127 - 51,585,168 (-)NCBI
ChlSab1.1 Ensembl251,577,833 - 51,580,297 (-)Ensembl
Vero_WHO_p1.0NW_0236660786,377,377 - 6,381,582 (-)NCBI
Foxa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474122,645,580 - 22,649,722 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000021439   ⟹   ENSCLAP00000021238
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541529,982,940 - 29,986,255 (-)Ensembl
RefSeq Acc Id: XM_005380957   ⟹   XP_005381014
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541529,982,940 - 29,986,255 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005380958   ⟹   XP_005381015
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541529,982,940 - 29,987,093 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005381014 (Get FASTA)   NCBI Sequence Viewer  
  XP_005381015 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005381015   ⟸   XM_005380958
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005381014   ⟸   XM_005380957
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000021238   ⟸   ENSCLAT00000021439


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014548 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000021238 ENTREZGENE
Ensembl Transcript ENSCLAT00000021439 ENTREZGENE
NCBI Gene Foxa2 ENTREZGENE