Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthase 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthase 2) Chinchilla lanigera
Analyze
Symbol: Hmgcs2
Name: 3-hydroxy-3-methylglutaryl-CoA synthase 2
RGD ID: 8823467
Description: ENCODES a protein that exhibits hydroxymethylglutaryl-CoA synthase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); adipose tissue development (ortholog); brain development (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency (ortholog); Colonic Neoplasms (ortholog); Experimental Diabetes Mellitus (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); hydroxymethylglutaryl-CoA synthase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543522,804,484 - 22,821,482 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543522,804,484 - 22,820,807 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References


Genomics

Comparative Map Data
Hmgcs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543522,804,484 - 22,821,482 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543522,804,484 - 22,820,807 (-)NCBIChiLan1.0ChiLan1.0
HMGCS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1119,748,002 - 119,768,905 (-)EnsemblGRCh38hg38GRCh38
GRCh381119,747,996 - 119,768,932 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371120,290,619 - 120,311,555 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361120,092,525 - 120,113,041 (-)NCBINCBI36hg18NCBI36
Build 341120,003,046 - 120,023,560NCBI
Celera1118,521,355 - 118,542,283 (-)NCBI
Cytogenetic Map1p12NCBI
HuRef1118,149,159 - 118,170,093 (-)NCBIHuRef
CHM1_11120,406,161 - 120,427,088 (-)NCBICHM1_1
Hmgcs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39398,187,747 - 98,218,054 (+)NCBIGRCm39mm39
GRCm39 Ensembl398,187,751 - 98,218,054 (+)Ensembl
GRCm38398,280,431 - 98,310,738 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl398,280,435 - 98,310,738 (+)EnsemblGRCm38mm10GRCm38
MGSCv37398,084,354 - 98,114,661 (+)NCBIGRCm37mm9NCBIm37
MGSCv36398,365,840 - 98,396,137 (+)NCBImm8
Celera399,679,562 - 99,709,869 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map342.74NCBI
Hmgcs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22185,875,609 - 185,903,505 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2185,875,616 - 185,902,130 (+)Ensembl
Rnor_6.02200,452,623 - 200,480,785 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2200,452,624 - 200,479,423 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02219,928,546 - 219,956,233 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42193,128,736 - 193,143,106 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12193,091,489 - 193,105,860 (+)NCBI
Celera2178,363,353 - 178,390,245 (+)NCBICelera
Cytogenetic Map2q34NCBI
HMGCS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11117,776,165 - 117,796,679 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,775,770 - 117,796,679 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0182,778,489 - 82,798,987 (+)NCBIMhudiblu_PPA_v0panPan3
HMGCS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11756,679,942 - 56,698,521 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1756,680,301 - 56,698,419 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1756,315,432 - 56,328,270 (-)NCBI
ROS_Cfam_1.01757,558,992 - 57,577,456 (-)NCBI
UMICH_Zoey_3.11756,594,625 - 56,613,171 (-)NCBI
UNSW_CanFamBas_1.01756,620,825 - 56,639,082 (-)NCBI
UU_Cfam_GSD_1.01757,237,948 - 57,256,436 (-)NCBI
Hmgcs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505810,015,851 - 10,037,163 (+)NCBI
SpeTri2.0NW_0049366274,451,847 - 4,473,163 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110260333
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4101,385,512 - 101,443,405 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14101,385,486 - 101,404,273 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
HMGCS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12014,018,669 - 14,040,934 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2014,019,692 - 14,041,016 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603816,649,801 - 16,670,981 (+)NCBIVero_WHO_p1.0
Hmgcs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477215,432,612 - 15,464,343 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000009369   ⟹   ENSCLAP00000009240
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543522,804,484 - 22,821,482 (-)Ensembl
RefSeq Acc Id: XM_005389089   ⟹   XP_005389146
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543522,804,484 - 22,820,807 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005389146 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005389146   ⟸   XM_005389089
- Sequence:
RefSeq Acc Id: ENSCLAP00000009240   ⟸   ENSCLAT00000009369


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006432 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000009240 ENTREZGENE
Ensembl Transcript ENSCLAT00000009369 ENTREZGENE
NCBI Gene Hmgcs2 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Hmgcs2  3-hydroxy-3-methylglutaryl-CoA synthase 2    3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)  Symbol and/or name change 5135510 APPROVED