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Gene: Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthase 2) Chinchilla lanigera
Symbol: Hmgcs2
Name: 3-hydroxy-3-methylglutaryl-CoA synthase 2
RGD ID: 8823467
Description: ENCODES a protein that exhibits hydroxymethylglutaryl-CoA synthase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acetyl-CoA metabolic process (ortholog); adipose tissue development (ortholog); brain development (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency (ortholog); Colonic Neoplasms (ortholog); Diabetes Mellitus, Experimental (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); hydroxymethylglutaryl-CoA synthase, mitochondrial
Homo sapiens (human) : HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2)  HGNC  Alliance
Mus musculus (house mouse) : Hmgcs2 (3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthase 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2)
Canis lupus familiaris (dog) : HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthase 2)
Sus scrofa (pig) : LOC110260333 (hydroxymethylglutaryl-CoA synthase, mitochondrial-like)
Chlorocebus sabaeus (African green monkey) : HMGCS2 (3-hydroxy-3-methylglutaryl-CoA synthase 2)
Heterocephalus glaber (naked mole-rat) : Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthase 2)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_00495543522,804,484 - 22,821,482 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543522,804,484 - 22,820,807 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Hmgcs2
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 8823467
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.