Scyl3 (SCY1 like pseudokinase 3) - Rat Genome Database

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Gene: Scyl3 (SCY1 like pseudokinase 3) Chinchilla lanigera
Analyze
Symbol: Scyl3
Name: SCY1 like pseudokinase 3
RGD ID: 8821036
Description: ENCODES a protein that exhibits identical protein binding (ortholog); kinase activity (ortholog); INVOLVED IN inflammatory response (ortholog); neuron development (ortholog); protein localization (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein-associating with the carboxyl-terminal domain of ezrin; SCY1-like 3; SCY1-like, kinase-like 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554627,448,893 - 7,476,840 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554627,443,841 - 7,477,596 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Scyl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554627,448,893 - 7,476,840 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554627,443,841 - 7,477,596 (+)NCBIChiLan1.0ChiLan1.0
SCYL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381169,849,631 - 169,894,268 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1169,849,631 - 169,894,267 (-)EnsemblGRCh38hg38GRCh38
GRCh371169,818,772 - 169,863,037 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361168,088,854 - 168,129,661 (-)NCBINCBI36Build 36hg18NCBI36
Celera1142,931,586 - 142,972,865 (-)NCBICelera
Cytogenetic Map1q24.2NCBI
HuRef1141,044,727 - 141,085,609 (-)NCBIHuRef
CHM1_11171,244,369 - 171,285,280 (-)NCBICHM1_1
T2T-CHM13v2.01169,205,381 - 169,249,993 (-)NCBIT2T-CHM13v2.0
Scyl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391163,756,669 - 163,782,695 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1163,756,669 - 163,782,695 (+)EnsemblGRCm39 Ensembl
GRCm381163,929,100 - 163,955,126 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1163,929,100 - 163,955,126 (+)EnsemblGRCm38mm10GRCm38
MGSCv371165,860,195 - 165,885,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361165,766,739 - 165,791,801 (+)NCBIMGSCv36mm8
Celera1166,370,534 - 166,395,607 (+)NCBICelera
Cytogenetic Map1H2.1- H2.2NCBI
cM Map171.23NCBI
Scyl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81378,811,595 - 78,836,202 (+)NCBIGRCr8
mRatBN7.21376,278,428 - 76,303,038 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1376,278,428 - 76,301,716 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1378,896,495 - 78,919,783 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01380,200,830 - 80,224,120 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01377,455,414 - 77,478,704 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01382,230,938 - 82,255,640 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1382,231,030 - 82,254,318 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01387,103,921 - 87,128,610 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41379,687,546 - 79,710,834 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11379,704,000 - 79,724,634 (+)NCBI
Celera1376,012,137 - 76,035,426 (+)NCBICelera
Cytogenetic Map13q23NCBI
SCYL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2179,855,292 - 79,912,359 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1179,541,059 - 79,584,939 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01145,299,266 - 145,383,511 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11149,056,553 - 149,100,201 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1149,057,194 - 149,095,445 (-)Ensemblpanpan1.1panPan2
SCYL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1728,751,604 - 28,796,042 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl728,751,707 - 28,795,756 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha728,283,039 - 28,327,661 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0728,553,281 - 28,597,911 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl728,553,472 - 28,597,906 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1728,401,988 - 28,446,611 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0728,437,213 - 28,481,830 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0728,673,927 - 28,718,589 (+)NCBIUU_Cfam_GSD_1.0
Scyl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934498,949,491 - 98,982,060 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648116,800,286 - 16,828,194 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648116,796,044 - 16,828,809 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCYL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl481,134,352 - 81,175,536 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1481,134,035 - 81,175,537 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2488,760,885 - 88,802,370 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SCYL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12559,157,208 - 59,215,074 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2559,156,992 - 59,198,614 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605560,812,493 - 60,873,673 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scyl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248267,749,332 - 7,779,145 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248267,748,995 - 7,783,157 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000009718   ⟹   ENSCLAP00000009589
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554627,448,893 - 7,476,840 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000009719   ⟹   ENSCLAP00000009590
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554627,448,893 - 7,476,840 (+)Ensembl
RefSeq Acc Id: XM_005398176   ⟹   XP_005398233
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554627,443,841 - 7,477,432 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005398178   ⟹   XP_005398235
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554627,443,980 - 7,477,432 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005398179   ⟹   XP_005398236
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554627,445,811 - 7,477,432 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005398180   ⟹   XP_005398237
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554627,443,841 - 7,477,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005398181   ⟹   XP_005398238
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554627,443,841 - 7,477,432 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005398238   ⟸   XM_005398181
- Peptide Label: isoform X2
- UniProtKB: A0A8C2V3U9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005398237   ⟸   XM_005398180
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YMI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005398233   ⟸   XM_005398176
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YMI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005398235   ⟸   XM_005398178
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YMI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005398236   ⟸   XM_005398179
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YMI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000009590   ⟸   ENSCLAT00000009719
RefSeq Acc Id: ENSCLAP00000009589   ⟸   ENSCLAT00000009718
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006650 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000009718 ENTREZGENE
  ENSCLAT00000009718.1 UniProtKB/TrEMBL
  ENSCLAT00000009719 ENTREZGENE
  ENSCLAT00000009719.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  HEAT_type_2 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
NCBI Gene Scyl3 ENTREZGENE
PANTHER PROTEIN-ASSOCIATING WITH THE CARBOXYL-TERMINAL DOMAIN OF EZRIN UniProtKB/TrEMBL
  SCY1-RELATED S/T PROTEIN KINASE-LIKE UniProtKB/TrEMBL
Pfam PK_Tyr_Ser-Thr UniProtKB/TrEMBL
PROSITE HEAT_REPEAT UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8C2V3U9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YMI2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Scyl3  SCY1 like pseudokinase 3    SCY1-like, kinase-like 3  Symbol and/or name change 5135510 APPROVED
2015-08-25 Scyl3  SCY1-like, kinase-like 3    SCY1-like 3 (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED