Spock1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1) - Rat Genome Database

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Gene: Spock1 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1) Chinchilla lanigera
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Symbol: Spock1
Name: SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
RGD ID: 8820137
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); cysteine-type endopeptidase inhibitor activity (ortholog); metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN central nervous system neuron differentiation (ortholog); negative regulation of cell-substrate adhesion (ortholog); negative regulation of neuron projection development (ortholog); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 31 (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); extracellular space (ortholog); neuromuscular junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1; testican-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540831,957,882 - 32,465,461 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540831,954,622 - 32,465,463 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Spock1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540831,957,882 - 32,465,461 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540831,954,622 - 32,465,463 (-)NCBIChiLan1.0ChiLan1.0
SPOCK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385136,975,298 - 137,499,326 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5136,975,298 - 137,598,379 (-)EnsemblGRCh38hg38GRCh38
GRCh375136,310,987 - 136,835,015 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365136,338,886 - 136,862,917 (-)NCBINCBI36Build 36hg18NCBI36
Build 345136,338,887 - 136,862,894NCBI
Celera5132,435,878 - 132,959,945 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5131,499,446 - 132,023,226 (-)NCBIHuRef
CHM1_15135,743,638 - 136,267,703 (-)NCBICHM1_1
T2T-CHM13v2.05137,497,979 - 138,022,024 (-)NCBIT2T-CHM13v2.0
Spock1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391357,569,008 - 58,056,194 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1357,569,008 - 58,056,146 (-)EnsemblGRCm39 Ensembl
GRCm381357,421,195 - 57,908,332 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1357,421,195 - 57,908,332 (-)EnsemblGRCm38mm10GRCm38
MGSCv371357,522,556 - 58,009,693 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361357,435,716 - 57,917,898 (-)NCBIMGSCv36mm8
Celera1358,485,985 - 58,970,735 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.5NCBI
Spock1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,746,892 - 7,227,034 (+)NCBIGRCr8
mRatBN7.2176,741,504 - 7,221,685 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,742,273 - 7,224,935 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx176,764,172 - 7,241,507 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0178,294,102 - 8,771,565 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0176,760,562 - 7,237,893 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0177,675,531 - 7,797,863 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl177,675,531 - 7,797,863 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,833,535 - 9,981,069 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41713,198,069 - 13,213,055 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11713,133,516 - 13,212,970 (+)NCBI
Celera176,844,778 - 7,323,370 (+)NCBICelera
Cytogenetic Map17p14NCBI
SPOCK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24132,267,651 - 132,785,725 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15130,407,210 - 130,925,284 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05132,372,283 - 132,890,168 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15138,512,523 - 138,730,331 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5138,512,523 - 138,797,416 (-)Ensemblpanpan1.1panPan2
SPOCK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11124,733,290 - 25,013,400 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1124,733,603 - 25,007,376 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1123,482,135 - 23,980,859 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01125,550,901 - 26,073,758 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1125,550,906 - 26,007,073 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11124,288,279 - 24,783,213 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01124,106,169 - 24,605,094 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01124,771,888 - 25,267,226 (-)NCBIUU_Cfam_GSD_1.0
Spock1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213124,975,526 - 125,469,022 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365974,000,400 - 4,156,221 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365974,000,433 - 4,493,920 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPOCK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2139,018,179 - 139,522,593 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12139,018,177 - 139,523,601 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22144,718,318 - 145,255,866 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPOCK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12339,676,750 - 40,192,565 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2339,676,558 - 39,965,037 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603437,701,157 - 38,216,801 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spock1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247339,556,763 - 10,080,703 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247339,556,024 - 10,080,703 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000019798   ⟹   ENSCLAP00000019605
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540831,957,882 - 32,465,461 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000019799   ⟹   ENSCLAP00000019606
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540831,957,882 - 32,465,461 (-)Ensembl
RefSeq Acc Id: XM_005376592   ⟹   XP_005376649
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540831,954,622 - 32,465,463 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376649 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000019605
  ENSCLAP00000019605.1
  ENSCLAP00000019606.1
RefSeq Acc Id: XP_005376649   ⟸   XM_005376592
- UniProtKB: A0A8C2VTX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000019606   ⟸   ENSCLAT00000019799
RefSeq Acc Id: ENSCLAP00000019605   ⟸   ENSCLAT00000019798
Protein Domains
Kazal-like   Thyroglobulin type-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013455 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019798 ENTREZGENE
  ENSCLAT00000019798.1 UniProtKB/TrEMBL
  ENSCLAT00000019799.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.30 UniProtKB/TrEMBL
  4.10.800.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  Kazal_dom UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  SPARC/Testican_Ca-bd-dom UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/TrEMBL
NCBI Gene Spock1 ENTREZGENE
PANTHER SPARC OSTEONECTIN UniProtKB/TrEMBL
  TESTICAN-1 UniProtKB/TrEMBL
Pfam Kazal_2 UniProtKB/TrEMBL
  SPARC_Ca_bdg UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
PROSITE KAZAL_2 UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/TrEMBL
SMART KAZAL UniProtKB/TrEMBL
  SM00211 UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF57610 UniProtKB/TrEMBL
UniProt A0A8C2VTX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VVW7_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-27 Spock1  SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1    SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1  Symbol and/or name change 5135510 APPROVED
2016-08-16 Spock1  SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1    sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1  Symbol and/or name change 5135510 APPROVED