LOC102019604 (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) - Rat Genome Database

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Gene: LOC102019604 (7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase) Chinchilla lanigera
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Symbol: LOC102019604
Name: 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
RGD ID: 8818191
Description: ENCODES a protein that exhibits sterol 12-alpha-hydroxylase activity (ortholog); INVOLVED IN bile acid biosynthetic process (ortholog); bile acid signaling pathway (ortholog); positive regulation of intestinal cholesterol absorption (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; bile acid signaling pathway; cerebrotendinous xanthomatosis pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); cholestasis (ortholog); congenital muscular dystrophy-dystroglycanopathy type A8 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542027,988,067 - 27,990,637 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data
LOC102019604
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542027,988,067 - 27,990,637 (+)NCBIChiLan1.0ChiLan1.0
CYP8B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,872,192 - 42,875,879 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl342,856,005 - 42,875,898 (-)EnsemblGRCh38hg38GRCh38
GRCh37342,913,684 - 42,917,371 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,888,688 - 42,892,637 (-)NCBINCBI36Build 36hg18NCBI36
Build 34342,888,687 - 42,892,637NCBI
Celera342,851,598 - 42,855,548 (-)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef342,956,837 - 42,960,786 (-)NCBIHuRef
CHM1_1342,863,684 - 42,867,633 (-)NCBICHM1_1
T2T-CHM13v2.0342,887,769 - 42,891,456 (-)NCBIT2T-CHM13v2.0
Cyp8b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,743,422 - 121,745,371 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9121,743,422 - 121,745,371 (-)EnsemblGRCm39 Ensembl
GRCm389121,914,356 - 121,916,305 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,914,356 - 121,916,305 (-)EnsemblGRCm38mm10GRCm38
MGSCv379121,823,474 - 121,825,423 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369121,763,054 - 121,764,989 (-)NCBIMGSCv36mm8
Celera9122,389,259 - 122,391,208 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.73NCBI
Cyp8b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28121,578,123 - 121,580,093 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,557,062 - 121,580,166 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8127,169,678 - 127,171,641 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08125,368,752 - 125,370,715 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08123,198,141 - 123,200,111 (-)NCBIRnor_WKY
Rnor_6.08130,548,418 - 130,550,388 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,548,418 - 130,550,388 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08129,723,896 - 129,725,866 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48127,018,908 - 127,020,878 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18127,038,644 - 127,040,615 (+)NCBI
Celera8120,702,850 - 120,704,820 (-)NCBICelera
Cytogenetic Map8q32NCBI
CYP8B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1342,839,601 - 42,841,106 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0342,775,679 - 42,779,440 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1343,838,315 - 43,842,260 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl343,824,423 - 43,842,716 (-)Ensemblpanpan1.1panPan2
CYP8B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12311,965,685 - 11,968,994 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2311,967,341 - 11,968,846 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2311,939,545 - 11,942,820 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02312,255,398 - 12,258,673 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2312,257,054 - 12,258,559 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12312,057,378 - 12,060,653 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02312,199,554 - 12,202,829 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02312,202,997 - 12,206,280 (-)NCBIUU_Cfam_GSD_1.0
LOC101977223
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118199,911,411 - 199,913,713 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366952,263,868 - 2,265,373 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366952,263,868 - 2,265,373 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP8B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1326,330,233 - 26,331,738 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11326,330,233 - 26,331,738 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CYP8B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1224,323,840 - 4,326,459 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl224,324,396 - 4,325,901 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041162,874,321 - 162,895,194 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005383508   ⟹   XP_005383565
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542027,988,067 - 27,990,637 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005383565 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005383565   ⟸   XM_005383508
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene LOC102019604 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 LOC102019604  7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase    7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase-like  Symbol and/or name change 5135510 APPROVED