Mat2b (methionine adenosyltransferase 2 non-catalytic beta subunit) - Rat Genome Database

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Gene: Mat2b (methionine adenosyltransferase 2 non-catalytic beta subunit) Chinchilla lanigera
Analyze
Symbol: Mat2b
Name: methionine adenosyltransferase 2 non-catalytic beta subunit
RGD ID: 8816421
Description: ENCODES a protein that exhibits enzyme binding (ortholog); methionine adenosyltransferase regulator activity (ortholog); INVOLVED IN S-adenosylmethionine biosynthetic process (ortholog); PARTICIPATES IN choline metabolic pathway; glycine N-methyltransferase deficiency pathway; homocystinuria pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN methionine adenosyltransferase complex (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methionine adenosyltransferase 2 subunit beta; methionine adenosyltransferase 2B; methionine adenosyltransferase II, beta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540816,910,414 - 16,924,663 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mat2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540816,910,414 - 16,924,663 (+)NCBIChiLan1.0ChiLan1.0
MAT2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385163,503,064 - 163,519,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5163,503,114 - 163,519,558 (+)EnsemblGRCh38hg38GRCh38
GRCh375162,930,070 - 162,946,360 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,862,809 - 162,878,906 (+)NCBINCBI36Build 36hg18NCBI36
Celera5158,964,332 - 158,980,423 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5158,029,749 - 158,046,037 (+)NCBIHuRef
CHM1_15162,362,532 - 162,378,812 (+)NCBICHM1_1
T2T-CHM13v2.05164,038,230 - 164,054,512 (+)NCBIT2T-CHM13v2.0
Mat2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,570,141 - 40,586,030 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1140,570,141 - 40,586,030 (-)EnsemblGRCm39 Ensembl
GRCm381140,679,314 - 40,695,203 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,679,314 - 40,695,203 (-)EnsemblGRCm38mm10GRCm38
MGSCv371140,492,816 - 40,506,115 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361140,522,737 - 40,536,036 (-)NCBIMGSCv36mm8
Celera1144,529,462 - 44,542,765 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.4NCBI
Mat2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,609,202 - 25,626,694 (-)NCBIGRCr8
mRatBN7.21025,106,928 - 25,122,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,106,930 - 25,122,777 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1029,861,993 - 29,877,026 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,350,532 - 29,365,565 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,837,185 - 24,852,218 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,832,096 - 25,848,045 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,832,072 - 25,847,994 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01025,686,294 - 25,701,795 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41025,713,132 - 25,718,879 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1024,666,794 - 24,680,351 (-)NCBICelera
Cytogenetic Map10q12NCBI
MAT2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24158,675,643 - 158,692,011 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15156,815,297 - 156,831,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05158,879,425 - 158,895,690 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15165,656,086 - 165,672,176 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5165,656,086 - 165,672,176 (+)Ensemblpanpan1.1panPan2
MAT2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,703,991 - 47,726,363 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,709,576 - 47,726,360 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha447,597,100 - 47,621,728 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0448,134,581 - 48,159,235 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl448,137,166 - 48,156,900 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1447,918,036 - 47,942,655 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0448,076,525 - 48,101,129 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0448,596,150 - 48,620,797 (-)NCBIUU_Cfam_GSD_1.0
Mat2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213102,094,901 - 102,111,644 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936515544,037 - 561,182 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936515544,218 - 561,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAT2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1660,255,358 - 60,274,135 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11660,255,541 - 60,274,228 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21665,065,436 - 65,111,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103244929
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12365,776,808 - 65,792,871 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2365,779,437 - 65,792,369 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666097990,267 - 1,006,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mat2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473326,297,653 - 26,306,942 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473326,296,920 - 26,309,228 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005376285   ⟹   XP_005376342
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540816,913,593 - 16,924,663 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005376286   ⟹   XP_005376343
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540816,910,414 - 16,924,663 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376342 (Get FASTA)   NCBI Sequence Viewer  
  XP_005376343 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018537
  ENSCLAP00000018537.1
  ENSCLAP00000018538
  ENSCLAP00000018538.1
Reference Protein Sequences
RefSeq Acc Id: XP_005376343   ⟸   XM_005376286
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VRD6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005376342   ⟸   XM_005376285
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VTA5 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
RmlD-like substrate binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012720 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018719 ENTREZGENE
  ENSCLAT00000018719.1 UniProtKB/TrEMBL
  ENSCLAT00000018720 ENTREZGENE
  ENSCLAT00000018720.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro dTDP_dehydrorham_reduct UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  RmlD-like-bd UniProtKB/TrEMBL
NCBI Gene Mat2b ENTREZGENE
PANTHER METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA UniProtKB/TrEMBL
  PTHR10491 UniProtKB/TrEMBL
Pfam RmlD_sub_bind UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A8C2VRD6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VTA5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-03-14 Mat2b  methionine adenosyltransferase 2 non-catalytic beta subunit  Mat2b  methionine adenosyltransferase 2B  Symbol and/or name change 5135510 APPROVED
2016-08-03 Mat2b  methionine adenosyltransferase 2B    methionine adenosyltransferase II, beta  Symbol and/or name change 5135510 APPROVED