Kntc1 (kinetochore associated 1) - Rat Genome Database

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Gene: Kntc1 (kinetochore associated 1) Chinchilla lanigera
Analyze
Symbol: Kntc1
Name: kinetochore associated 1
RGD ID: 8816217
Description: INVOLVED IN mitotic spindle assembly checkpoint signaling (ortholog); ASSOCIATED WITH genetic disease (ortholog); prostate cancer (ortholog); FOUND IN actin cytoskeleton (ortholog); cytosol (ortholog); kinetochore microtubule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kinetochore-associated protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,043,456 - 6,115,816 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,040,964 - 6,119,814 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Kntc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,043,456 - 6,115,816 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,040,964 - 6,119,814 (-)NCBIChiLan1.0ChiLan1.0
KNTC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812122,527,249 - 122,626,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12122,527,246 - 122,626,396 (+)EnsemblGRCh38hg38GRCh38
GRCh3712123,011,796 - 123,110,943 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,577,762 - 121,676,900 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412121,536,688 - 121,635,826NCBI
Celera12122,603,808 - 122,703,457 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12119,972,346 - 120,071,310 (+)NCBIHuRef
CHM1_112122,980,095 - 123,079,246 (+)NCBICHM1_1
T2T-CHM13v2.012122,522,498 - 122,621,883 (+)NCBIT2T-CHM13v2.0
Kntc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395123,887,755 - 123,959,656 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5123,887,779 - 123,959,656 (+)EnsemblGRCm39 Ensembl
GRCm385123,749,692 - 123,821,593 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5123,749,716 - 123,821,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv375124,199,735 - 124,271,602 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365124,010,057 - 124,082,211 (+)NCBIMGSCv36mm8
Celera5120,826,139 - 120,897,375 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map563.17NCBI
Kntc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81238,429,925 - 38,500,564 (-)NCBIGRCr8
mRatBN7.21232,769,020 - 32,839,617 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,769,020 - 32,839,561 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1233,947,524 - 34,018,036 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01234,558,878 - 34,629,387 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01233,610,753 - 33,681,265 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01238,200,463 - 38,274,162 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,200,463 - 38,274,036 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01240,072,618 - 40,146,664 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,906,847 - 33,977,070 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,770,234 - 33,838,191 (-)NCBI
Celera1234,454,628 - 34,525,016 (-)NCBICelera
Cytogenetic Map12q15-q16NCBI
KNTC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,619,040 - 130,717,739 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,615,416 - 130,714,115 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012120,129,557 - 120,228,384 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112124,351,508 - 124,448,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12124,351,508 - 124,448,624 (+)Ensemblpanpan1.1panPan2
KNTC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1266,777,667 - 6,867,798 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl266,777,383 - 6,865,016 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha266,949,518 - 7,027,944 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,038,832 - 7,118,419 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,039,041 - 7,118,276 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,970,904 - 7,049,409 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,064,422 - 7,142,689 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,018,155 - 7,097,743 (-)NCBIUU_Cfam_GSD_1.0
Kntc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118157,455,196 - 157,543,715 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365581,937,048 - 2,016,447 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365581,936,946 - 2,016,474 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KNTC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1430,153,702 - 30,241,829 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11430,154,918 - 30,241,988 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21431,905,350 - 31,985,822 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KNTC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111117,866,814 - 117,966,297 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11117,869,711 - 117,963,907 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037127,355,819 - 127,456,232 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kntc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474722,669,297 - 22,758,226 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474722,667,872 - 22,758,411 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000018562   ⟹   ENSCLAP00000018382
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554826,043,456 - 6,115,816 (-)Ensembl
RefSeq Acc Id: XM_005403078   ⟹   XP_005403135
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554826,040,964 - 6,119,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005403079   ⟹   XP_005403136
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554826,040,964 - 6,119,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013503705   ⟹   XP_013359159
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554826,040,964 - 6,119,705 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005403135 (Get FASTA)   NCBI Sequence Viewer  
  XP_005403136 (Get FASTA)   NCBI Sequence Viewer  
  XP_013359159 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018382
  ENSCLAP00000018382.1
Reference Protein Sequences
RefSeq Acc Id: XP_005403136   ⟸   XM_005403079
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VSX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005403135   ⟸   XM_005403078
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VSX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013359159   ⟸   XM_013503705
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VSX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000018382   ⟸   ENSCLAT00000018562
Protein Domains
RZZ complex subunit KNTC1/ROD C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012600 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000018562 ENTREZGENE
  ENSCLAT00000018562.1 UniProtKB/TrEMBL
InterPro RZZ-complex_KNTC1/ROD_C UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene Kntc1 ENTREZGENE
PANTHER KINETOCHORE-ASSOCIATED PROTEIN 1 UniProtKB/TrEMBL
  KINETOCHORE-ASSOCIATED PROTEIN 1 UniProtKB/TrEMBL
Pfam Rod_C UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A8C2VSX5 ENTREZGENE, UniProtKB/TrEMBL