Nedd4l (NEDD4 like E3 ubiquitin protein ligase) - Rat Genome Database

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Gene: Nedd4l (NEDD4 like E3 ubiquitin protein ligase) Chinchilla lanigera
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Symbol: Nedd4l
Name: NEDD4 like E3 ubiquitin protein ligase
RGD ID: 8813366
Description: ENCODES a protein that exhibits potassium channel inhibitor activity (ortholog); potassium channel regulator activity (ortholog); sodium channel inhibitor activity (ortholog); INVOLVED IN negative regulation of potassium ion transmembrane transport (ortholog); negative regulation of potassium ion transmembrane transporter activity (ortholog); negative regulation of protein localization to cell surface (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH cleft palate (ortholog); dilated cardiomyopathy (ortholog); endometriosis (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase NEDD4-like; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540242,339,380 - 42,688,714 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540242,339,380 - 42,688,661 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Nedd4l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540242,339,380 - 42,688,714 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540242,339,380 - 42,688,661 (+)NCBIChiLan1.0ChiLan1.0
NEDD4L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1858,044,226 - 58,401,540 (+)EnsemblGRCh38hg38GRCh38
GRCh381858,044,226 - 58,401,540 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371855,711,458 - 56,068,772 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361853,862,778 - 54,216,369 (+)NCBINCBI36hg18NCBI36
Build 341853,862,777 - 54,216,369NCBI
Celera1852,429,273 - 52,785,147 (+)NCBI
Cytogenetic Map18q21.31NCBI
HuRef1852,421,551 - 52,777,135 (+)NCBIHuRef
CHM1_11855,707,037 - 56,063,999 (+)NCBICHM1_1
Nedd4l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391865,017,551 - 65,350,897 (+)NCBIGRCm39mm39
GRCm39 Ensembl1865,020,776 - 65,350,899 (+)Ensembl
GRCm381864,884,480 - 65,217,826 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1864,887,705 - 65,217,828 (+)EnsemblGRCm38mm10GRCm38
MGSCv371865,047,410 - 65,377,480 (+)NCBIGRCm37mm9NCBIm37
MGSCv361865,149,263 - 65,338,676 (+)NCBImm8
Celera1866,271,347 - 66,493,213 (+)NCBICelera
Cytogenetic Map18E1NCBI
Nedd4l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21858,393,759 - 58,726,709 (+)NCBI
Rnor_6.0 Ensembl1860,392,376 - 60,719,720 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01860,392,376 - 60,719,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01859,595,643 - 59,921,504 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41861,134,242 - 61,477,040 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11861,528,414 - 61,549,290 (+)NCBI
Celera1856,529,040 - 56,853,871 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
NEDD4L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11854,762,516 - 55,122,236 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1854,867,149 - 55,123,423 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01851,428,077 - 51,792,995 (+)NCBIMhudiblu_PPA_v0panPan3
NEDD4L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1117,629,163 - 17,858,471 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl117,633,591 - 17,950,072 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha118,613,069 - 18,951,799 (-)NCBI
ROS_Cfam_1.0117,509,482 - 17,848,443 (-)NCBI
UMICH_Zoey_3.1117,567,699 - 17,905,982 (-)NCBI
UNSW_CanFamBas_1.0117,465,765 - 17,804,137 (-)NCBI
UU_Cfam_GSD_1.0117,733,960 - 18,072,781 (-)NCBI
Nedd4l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494430,867,247 - 31,171,348 (-)NCBI
SpeTri2.0NW_0049364976,106,284 - 6,318,339 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEDD4L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1162,364,055 - 162,737,492 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11162,364,053 - 162,736,515 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NEDD4L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11821,326,276 - 21,683,817 (-)NCBI
ChlSab1.1 Ensembl1821,327,567 - 21,683,905 (-)Ensembl
Vero_WHO_p1.0NW_0236660603,882,156 - 4,244,040 (+)NCBI
Nedd4l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247923,553,185 - 3,903,288 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000012302   ⟹   ENSCLAP00000012160
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540242,339,380 - 42,688,714 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000012303   ⟹   ENSCLAP00000012161
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540242,452,739 - 42,683,821 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000012304   ⟹   ENSCLAP00000012162
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540242,540,253 - 42,688,714 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000012305   ⟹   ENSCLAP00000012163
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540242,540,253 - 42,688,714 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000012306   ⟹   ENSCLAP00000012164
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540242,596,859 - 42,688,714 (+)Ensembl
RefSeq Acc Id: XM_005372981   ⟹   XP_005373038
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,539,768 - 42,688,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005372983   ⟹   XP_005373040
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,539,770 - 42,688,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005372986   ⟹   XP_005373043
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,539,767 - 42,688,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005372988   ⟹   XP_005373045
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,339,380 - 42,688,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510994   ⟹   XP_013366448
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,539,765 - 42,688,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510999   ⟹   XP_013366453
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,539,767 - 42,688,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511005   ⟹   XP_013366459
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,596,859 - 42,688,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511013   ⟹   XP_013366467
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540242,483,769 - 42,688,661 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005373045   ⟸   XM_005372988
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_005373043   ⟸   XM_005372986
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005373038   ⟸   XM_005372981
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005373040   ⟸   XM_005372983
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013366467   ⟸   XM_013511013
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_013366448   ⟸   XM_013510994
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013366453   ⟸   XM_013510999
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013366459   ⟸   XM_013511005
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSCLAP00000012161   ⟸   ENSCLAT00000012303
RefSeq Acc Id: ENSCLAP00000012160   ⟸   ENSCLAT00000012302
RefSeq Acc Id: ENSCLAP00000012164   ⟸   ENSCLAT00000012306
RefSeq Acc Id: ENSCLAP00000012163   ⟸   ENSCLAT00000012305
RefSeq Acc Id: ENSCLAP00000012162   ⟸   ENSCLAT00000012304


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000008387 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000012160 ENTREZGENE
  ENSCLAP00000012163 ENTREZGENE
  ENSCLAP00000012164 ENTREZGENE
Ensembl Transcript ENSCLAT00000012302 ENTREZGENE
  ENSCLAT00000012305 ENTREZGENE
  ENSCLAT00000012306 ENTREZGENE
NCBI Gene Nedd4l ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-09 Nedd4l  NEDD4 like E3 ubiquitin protein ligase    neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase  Symbol and/or name change 5135510 APPROVED