Mtcl1 (microtubule crosslinking factor 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Mtcl1 (microtubule crosslinking factor 1) Chinchilla lanigera
Analyze
Symbol: Mtcl1
Name: microtubule crosslinking factor 1
RGD ID: 8813245
Description: ENCODES a protein that exhibits microtubule binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN chromosome segregation (ortholog); establishment or maintenance of epithelial cell apical/basal polarity (ortholog); microtubule bundle formation (ortholog); ASSOCIATED WITH autosomal dominant cerebellar ataxia (ortholog); cerebellar ataxia (ortholog); chromosome 18p deletion syndrome (ortholog); FOUND IN apicolateral plasma membrane (ortholog); cytoskeleton (ortholog); kinetochore (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: microtubule cross-linking factor 1; SOGA family member 2; Soga2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554022,979,547 - 3,076,283 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554022,980,539 - 3,076,283 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mtcl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554022,979,547 - 3,076,283 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554022,980,539 - 3,076,283 (-)NCBIChiLan1.0ChiLan1.0
MTCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38188,705,556 - 8,832,778 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl188,705,556 - 8,832,778 (+)EnsemblGRCh38hg38GRCh38
GRCh37188,705,554 - 8,832,776 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36188,707,369 - 8,822,074 (+)NCBINCBI36Build 36hg18NCBI36
Celera188,601,536 - 8,716,876 (+)NCBICelera
Cytogenetic Map18p11.22NCBI
HuRef188,681,428 - 8,796,763 (+)NCBIHuRef
CHM1_1188,717,549 - 8,832,980 (+)NCBICHM1_1
T2T-CHM13v2.0188,868,615 - 8,995,758 (+)NCBIT2T-CHM13v2.0
Mtcl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,643,975 - 66,760,672 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1766,643,977 - 66,756,745 (-)EnsemblGRCm39 Ensembl
GRCm381766,336,980 - 66,449,806 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1766,336,982 - 66,449,750 (-)EnsemblGRCm38mm10GRCm38
MGSCv371766,686,322 - 66,799,090 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361766,241,933 - 66,290,855 (-)NCBIMGSCv36mm8
Celera1770,637,666 - 70,750,457 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1735.3NCBI
Mtcl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89113,722,138 - 113,888,413 (-)NCBIGRCr8
mRatBN7.29106,305,282 - 106,441,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9106,321,098 - 106,442,203 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.09114,493,901 - 114,632,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9114,491,419 - 114,619,711 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09113,981,913 - 114,136,747 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49105,456,824 - 105,574,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19105,636,246 - 105,783,556 (-)NCBI
Celera9103,496,748 - 103,614,716 (-)NCBICelera
Cytogenetic Map9q37NCBI
MTCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21729,621,291 - 29,747,178 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11815,313,886 - 15,439,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1187,734,076 - 7,906,953 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl187,737,903 - 7,906,958 (-)Ensemblpanpan1.1panPan2
MTCL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1774,840,271 - 74,967,849 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl774,840,032 - 74,967,305 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha774,230,206 - 74,358,609 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0774,890,596 - 75,019,099 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl774,890,596 - 75,019,104 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1774,592,893 - 74,721,307 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0774,611,401 - 74,739,900 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0774,917,008 - 75,045,339 (+)NCBIUU_Cfam_GSD_1.0
Mtcl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494471,873,016 - 72,002,758 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366702,388,908 - 2,516,875 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366702,388,839 - 2,516,758 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl699,062,354 - 99,178,468 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1699,062,347 - 99,178,570 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2692,351,813 - 92,452,978 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11867,666,982 - 67,792,792 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1867,667,690 - 67,788,981 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605042,606,815 - 42,732,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtcl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477017,703,586 - 17,788,192 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477017,702,793 - 17,788,861 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000015926   ⟹   ENSCLAP00000015763
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554022,979,547 - 3,076,283 (-)Ensembl
RefSeq Acc Id: XM_005372609   ⟹   XP_005372666
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554022,980,539 - 3,076,283 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005372666 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000015763
  ENSCLAP00000015763.1
Reference Protein Sequences
RefSeq Acc Id: XP_005372666   ⟸   XM_005372609
- UniProtKB: A0A8C2VPG1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000015763   ⟸   ENSCLAT00000015926
Protein Domains
DUF4482


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010836 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015926 ENTREZGENE
  ENSCLAT00000015926.1 UniProtKB/TrEMBL
InterPro DUF4482 UniProtKB/TrEMBL
  SOGA UniProtKB/TrEMBL
NCBI Gene Soga2 ENTREZGENE
PANTHER MICROTUBULE CROSS-LINKING FACTOR 1 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam DUF4482 UniProtKB/TrEMBL
  SOGA UniProtKB/TrEMBL
UniProt A0A8C2VPG1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Mtcl1  microtubule crosslinking factor 1  Soga2  SOGA family member 2  Symbol and/or name change 5135510 APPROVED