Alpl (alkaline phosphatase, biomineralization associated)

Advanced Search (OLGA)

Gene: Alpl (alkaline phosphatase, biomineralization associated) Chinchilla lanigera

Analyze

Symbol:

Alpl

Name:

alkaline phosphatase, biomineralization associated

RGD ID:

8809632

Description:

ENCODES a protein that exhibits alkaline phosphatase activity (ortholog); calcium ion binding (ortholog); phosphoamidase activity (ortholog); INVOLVED IN bone mineralization (ortholog); calcium ion homeostasis (ortholog); cellular homeostasis (ortholog); PARTICIPATES IN hypophosphatasia pathway; vitamin B6 metabolic pathway; ASSOCIATED WITH 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ortholog); adult hypophosphatasia (ortholog); alpha thalassemia-X-linked intellectual disability syndrome (ortholog); FOUND IN extracellular matrix (ortholog); extracellular membrane-bounded organelle (ortholog); extracellular space (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

alkaline phosphatase, liver/bone/kidney; alkaline phosphatase, tissue-nonspecific isozyme

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	1,820,174 - 1,874,226 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	1,820,212 - 1,873,877 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-hydroxy-3-methylglutaryl-CoA lyase deficiency (ISO)

adult hypophosphatasia (ISO)

alpha thalassemia-X-linked intellectual disability syndrome (ISO)

Alveolar Bone Loss (ISO)

Animal Disease Models (ISO)

arteriosclerosis (ISO)

calcinosis (ISO)

childhood hypophosphatasia (ISO)

congenital disorder of glycosylation Ir (ISO)

connective tissue disease (ISO)

familial combined hyperlipidemia (ISO)

genetic disease (ISO)

Germ Cell and Embryonal Neoplasms (ISO)

Heat Stroke (ISO)

Hypercholesterolemia (ISO)

hyperprolinemia type 2 (ISO)

hypophosphatasia (ISO)

in situ carcinoma (ISO)

infantile hypophosphatasia (ISO)

liver disease (ISO)

Metabolic Bone Diseases (ISO)

Metabolic Syndrome (ISO)

microcephaly (ISO)

MICROMELIA (ISO)

Odontohypophosphatasia (ISO)

osteochondrodysplasia (ISO)

osteogenesis imperfecta (ISO)

Parkinson's disease 6 (ISO)

Perinatal Lethal Hypophosphatasia (ISO)

secondary hyperparathyroidism (ISO)

steatotic liver disease (ISO)

uremia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Cellular Component

extracellular matrix (ISO)

extracellular membrane-bounded organelle (ISO)

extracellular space (ISO)

mitochondrial intermembrane space (ISO)

mitochondrial membrane (ISO)

plasma membrane (ISO)

Molecular Function

alkaline phosphatase activity (ISO)

calcium ion binding (ISO)

phosphoamidase activity (ISO)

phosphoethanolamine phosphatase activity (ISO)

protein binding (ISO)

pyridoxal phosphatase activity (ISO)

pyrophosphatase activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

hypophosphatasia pathway (ISO)

vitamin B6 metabolic pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Alpl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955452	1,820,174 - 1,874,226 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955452	1,820,212 - 1,873,877 (+)	NCBI	ChiLan1.0	ChiLan1.0

ALPL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	21,508,984 - 21,578,410 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	21,509,397 - 21,578,410 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	21,835,477 - 21,904,903 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	21,708,445 - 21,777,492 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	21,581,174 - 21,650,208	NCBI
Celera	1	20,158,568 - 20,227,624 (+)	NCBI		Celera
Cytogenetic Map	1	p36.12	NCBI
HuRef	1	20,079,620 - 20,148,672 (+)	NCBI		HuRef
CHM1_1	1	21,947,891 - 22,016,920 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	21,332,916 - 21,402,323 (+)	NCBI		T2T-CHM13v2.0

Alpl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	137,469,042 - 137,523,695 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	137,469,044 - 137,523,695 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	137,741,731 - 137,796,384 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	137,741,733 - 137,796,384 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	137,297,647 - 137,352,292 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	137,013,815 - 137,068,399 (-)	NCBI		MGSCv36	mm8
Celera	4	135,949,159 - 136,007,413 (-)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	70.02	NCBI

Alpl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	155,234,770 - 155,289,785 (-)	NCBI		GRCr8
mRatBN7.2	5	149,951,397 - 150,006,424 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	149,951,409 - 150,006,446 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	152,647,183 - 152,702,235 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	154,421,476 - 154,476,524 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	154,403,485 - 154,458,535 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	156,086,496 - 156,141,513 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	156,086,497 - 156,141,537 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	159,841,916 - 159,897,391 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	156,501,739 - 156,558,727 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	156,511,778 - 156,568,766 (-)	NCBI
Celera	5	148,347,371 - 148,402,292 (-)	NCBI		Celera
RH 3.4 Map	5	1009.6	RGD
Cytogenetic Map	5	q36	NCBI

ALPL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	205,360,590 - 205,430,382 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	204,472,488 - 204,542,348 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	20,702,509 - 20,772,301 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	21,667,732 - 21,736,688 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	21,667,732 - 21,736,688 (+)	Ensembl	panpan1.1		panPan2

ALPL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	77,559,791 - 77,614,102 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	77,559,791 - 77,614,820 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	74,073,609 - 74,088,831 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	78,128,381 - 78,182,495 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	78,128,381 - 78,182,455 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	74,947,430 - 74,962,684 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	75,958,433 - 75,973,647 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	76,961,389 - 76,976,632 (-)	NCBI		UU_Cfam_GSD_1.0

Alpl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	41,362,174 - 41,405,120 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	7,209,093 - 7,229,989 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	7,209,196 - 7,229,899 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALPL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	79,589,045 - 79,649,644 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	79,589,695 - 79,649,646 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

ALPL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	111,055,583 - 111,124,143 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	111,055,558 - 111,081,850 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	5,163,162 - 5,231,388 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Alpl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	6,393,765 - 6,447,829 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	6,393,741 - 6,447,739 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013519688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013519690	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01043868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01043869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBCE01004528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000011100 ⟹ ENSCLAP00000010965

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955452	1,820,174 - 1,874,226 (+)	Ensembl

Ensembl Acc Id:

ENSCLAT00000011101 ⟹ ENSCLAP00000010966

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955452	1,820,174 - 1,874,226 (+)	Ensembl

RefSeq Acc Id:

XM_013519688 ⟹ XP_013375142

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	1,820,212 - 1,873,877 (+)	NCBI

Sequence:

show sequence

CGGCGGGGGAGGTGGCCCGGGCCGCGTCGCGCTCCCGCCACCCCGCGCCCACTCCCCGCTCCCC
GAGCGCACGCCCCTGGTGCCAGGACAGACCCTCGCCCACGAGTTCCGCGCAGAGAGAAGGCCCA
ACTAGCTTGGTACCTCAGTGTCTGTCCCCATGCCTGGCCTCTAATAGATGTTCAACAAATACTT
GTTGAATGAATCAAGGATGAATACCTGCATGAAGAAGTGACCTCCAGAGATGCGCCCCATGTCT
CTCTGTCTCTTTTTTTCCCCTCTCTGATGTCTAGGATTGGAACATCAATTAACGGCTGATCACT
ACCAGCCCACTTCCTCCCGCCCACGTCCATCACATCTCTGGGTTCCAGTGAAGAAGCAGGTCTT
GGGGTGCACCATGATCTCACCATTCTTAGTACTGGCCATTGGTACCTGCCTTACCAACTCTTTA
GTGCCAGAGAAAGAGAAAGACCCCAGTTACTGGCGGAAACAAGCCCAAGCGACCCTGAAAAATG
CCCTGGCGCTTCAGAAGCTCAATACCAACGTGGCCAAGAATGTCATCATGTTCCTGGGAGATGG
GATGGGCGTCTCCACGGTGACAGCCGCCCGAATCCTCAAGGGTCAGCTCCACCACAACCCTGGC
GAGGAGACCATGCTGGAGATGGACAAATTCCCCTTCGTGGCCCTATCCAAGACGTACAACACCA
ACGCGCAGGTCCCCGACAGCGCGGGCACCGCCACCGCTTACCTATGCGGAGTGAAGGCCAATGA
GGGCACCGTGGGGGTGAGCGCAGCCACCGAGCGCACCCGGTGCAACACCACCCAGGGCAACGAG
GTCACCTCCATCCTGAGCTGGGCCAAGGACGCTGGGAAATCCGTGGGCATCGTGACAACCACAC
GGGTGAACCACGCCACCCCCAGTGCCGCCTACGCCCACTCAGCCGACCGGGACTGGTACTCAGA
CAACGAGATGCCCCCGGAGGCCCTGAGCCAGGGCTGCAAGGACATCGCCTTCCAGCTCATGCAC
AACATCAAGGACATCGATGTGATCATGGGGGGTGGCCGGAAGTACATGTACCCCAAGAACAGAA
CCGACGTGGAGTACAAGATGGACGAGAAGTCCAGGGGCACGAGGCTGGACGGCCTGAACCTCAT
CGACAAATGGAAGAGCTTTAAACCAAGTAACAAGCACTCGCACTTTGTCTGGAACCGCACCGAG
CTCCTGGCACTCAACCTTCACACCGTGGACTACCTCTTGGGTCTGTTTGAGCCTGGGGACATGC
AGTACGAGCTGAACAGAAACAACGAGACCGACCCTTCGCTCTCTGAGATGGTGGAGGTGGCCAT
CAAGATCCTGAAGAAGAACCCCAAAGGCTTCTTCTTGCTGGTGGAAGGAGGCAGGATTGACCAC
GGACACCATGAGGGCAAAGCCAAGCAGGCGCTGCACGAGGCGGTGGAGATGGACCAGGCAATCG
GACAGGCCGGTGCCATGACCTCTTTGAACGACACACTGACTGTGGTCACGGCTGACCATTCCCA
CGTCTTCACCTTCGGCGGATACACACCTCGGGGCAACTCTATCTTTGGTCTGGCCCCCATGGTG
AGCGACACGGACAAGAAGCCTTTCACTGCCATCCTGTACGGCAACGGGCCTGGCTACAAGGTAG
TGGATGGAGAGCGAGAAAACGTCTCCATGGTGGACTATGCTCACAACAACTACCAGGCCCAGTC
TGCTGTGCCCCTGCGCCATGAGACGCATGGCGGAGAGGACGTGGCCGTCTTTGCCAAGGGCCCC
ATGGCGCACCTGCTGCACGGCGTCCACGAGCAGAACTACATCCCGCACATGATGGCCTACGCAG
CCTGCATCGGGGCCAACCTCGACCACTGTGCTCAGGCCGGCTCTGCGGGCAGCCCTGCCCTGGC
GCCCCTGCTGCTCCTGCTGGTGCTGAGTCCCTTGCATGTCCTCTTCTGAGGGCTTGGGCCCAAC
ACCTGGGAGCCCACGACAGATGGCCGGGCTCTCTCACACCGCTGCCCGCCCTGGGCAGCCCGCA
CCTCAAGGGCAGGGAGGCCGAGGCCTCCAGAACCTCTGCAGCTGCCAGGAGGGGGACCCAGGAA
CCAAAGTCTGCTGCCTGCCTCACTCCCCTCTGGAATCCTCCACAGGCTGGCCTGATACCTGGCC
TCTGGGCCTGGCTCCCTCCCCGCTGCCCTTTGGCCAACAGGATAGGTTCATCCTGGGCACTCAG
AGCATAGACTGCAGGAATCCTGAAAGCATCTTATTTTTCTAGCAGATATATTTCTCCACACCCA
GAAGCCTCCATGGAACATTCCAGACCTGATGGACCCTCCCATCCCCTCTCCCTCTGGAACACAC
TAGGCCCCACGCTCAGTCCCCCAAGCCACGCCCTGCCTGCTGTGGAGACCGCCTCTCCTCGGCC
TAGGAGTCTCTTGCCCACTCCAAGGGTCCTGCGGCTCCCAGGAAGCCACCTCCTAGGCCTGGCT
GCCCACCAGGGCGGCCGGGCTGGGCAGAGTGACCTGGCGGGTTACGTACGCCACAGTTCCAAAC
ACACATGCCAGCTCCTCTCTGAGGCGACTCTCCTGTTTGGAACTAAAAAAAAAAAAAAAAAAAT
TCTCTTTTTGGTGTTGGTTAAAAGGGAACACAAAACATTTAAATAAAACTTTCCAAATATTTCT
GAGGACA

hide sequence

RefSeq Acc Id:

XM_013519689 ⟹ XP_013375143

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	1,820,212 - 1,873,877 (+)	NCBI

Sequence:

show sequence

CGGCGGGGGAGGTGGCCCGGGCCGCGTCGCGCTCCCGCCACCCCGCGCCCACTCCCCGCTCCCC
GAGCGCACGCCCCTGGTGCCAGGACAGACCCTCGCCCACGAGTTCCGCGCAGGATTGGAACATC
AATTAACGGCTGATCACTACCAGCCCACTTCCTCCCGCCCACGTCCATCACATCTCTGGGTTCC
AGTGAAGAAGCAGGTCTTGGGGTGCACCATGATCTCACCATTCTTAGTACTGGCCATTGGTACC
TGCCTTACCAACTCTTTAGTGCCAGAGAAAGAGAAAGACCCCAGTTACTGGCGGAAACAAGCCC
AAGCGACCCTGAAAAATGCCCTGGCGCTTCAGAAGCTCAATACCAACGTGGCCAAGAATGTCAT
CATGTTCCTGGGAGATGGGATGGGCGTCTCCACGGTGACAGCCGCCCGAATCCTCAAGGGTCAG
CTCCACCACAACCCTGGCGAGGAGACCATGCTGGAGATGGACAAATTCCCCTTCGTGGCCCTAT
CCAAGACGTACAACACCAACGCGCAGGTCCCCGACAGCGCGGGCACCGCCACCGCTTACCTATG
CGGAGTGAAGGCCAATGAGGGCACCGTGGGGGTGAGCGCAGCCACCGAGCGCACCCGGTGCAAC
ACCACCCAGGGCAACGAGGTCACCTCCATCCTGAGCTGGGCCAAGGACGCTGGGAAATCCGTGG
GCATCGTGACAACCACACGGGTGAACCACGCCACCCCCAGTGCCGCCTACGCCCACTCAGCCGA
CCGGGACTGGTACTCAGACAACGAGATGCCCCCGGAGGCCCTGAGCCAGGGCTGCAAGGACATC
GCCTTCCAGCTCATGCACAACATCAAGGACATCGATGTGATCATGGGGGGTGGCCGGAAGTACA
TGTACCCCAAGAACAGAACCGACGTGGAGTACAAGATGGACGAGAAGTCCAGGGGCACGAGGCT
GGACGGCCTGAACCTCATCGACAAATGGAAGAGCTTTAAACCAAGTAACAAGCACTCGCACTTT
GTCTGGAACCGCACCGAGCTCCTGGCACTCAACCTTCACACCGTGGACTACCTCTTGGGTCTGT
TTGAGCCTGGGGACATGCAGTACGAGCTGAACAGAAACAACGAGACCGACCCTTCGCTCTCTGA
GATGGTGGAGGTGGCCATCAAGATCCTGAAGAAGAACCCCAAAGGCTTCTTCTTGCTGGTGGAA
GGAGGCAGGATTGACCACGGACACCATGAGGGCAAAGCCAAGCAGGCGCTGCACGAGGCGGTGG
AGATGGACCAGGCAATCGGACAGGCCGGTGCCATGACCTCTTTGAACGACACACTGACTGTGGT
CACGGCTGACCATTCCCACGTCTTCACCTTCGGCGGATACACACCTCGGGGCAACTCTATCTTT
GGTCTGGCCCCCATGGTGAGCGACACGGACAAGAAGCCTTTCACTGCCATCCTGTACGGCAACG
GGCCTGGCTACAAGGTAGTGGATGGAGAGCGAGAAAACGTCTCCATGGTGGACTATGCTCACAA
CAACTACCAGGCCCAGTCTGCTGTGCCCCTGCGCCATGAGACGCATGGCGGAGAGGACGTGGCC
GTCTTTGCCAAGGGCCCCATGGCGCACCTGCTGCACGGCGTCCACGAGCAGAACTACATCCCGC
ACATGATGGCCTACGCAGCCTGCATCGGGGCCAACCTCGACCACTGTGCTCAGGCCGGCTCTGC
GGGCAGCCCTGCCCTGGCGCCCCTGCTGCTCCTGCTGGTGCTGAGTCCCTTGCATGTCCTCTTC
TGAGGGCTTGGGCCCAACACCTGGGAGCCCACGACAGATGGCCGGGCTCTCTCACACCGCTGCC
CGCCCTGGGCAGCCCGCACCTCAAGGGCAGGGAGGCCGAGGCCTCCAGAACCTCTGCAGCTGCC
AGGAGGGGGACCCAGGAACCAAAGTCTGCTGCCTGCCTCACTCCCCTCTGGAATCCTCCACAGG
CTGGCCTGATACCTGGCCTCTGGGCCTGGCTCCCTCCCCGCTGCCCTTTGGCCAACAGGATAGG
TTCATCCTGGGCACTCAGAGCATAGACTGCAGGAATCCTGAAAGCATCTTATTTTTCTAGCAGA
TATATTTCTCCACACCCAGAAGCCTCCATGGAACATTCCAGACCTGATGGACCCTCCCATCCCC
TCTCCCTCTGGAACACACTAGGCCCCACGCTCAGTCCCCCAAGCCACGCCCTGCCTGCTGTGGA
GACCGCCTCTCCTCGGCCTAGGAGTCTCTTGCCCACTCCAAGGGTCCTGCGGCTCCCAGGAAGC
CACCTCCTAGGCCTGGCTGCCCACCAGGGCGGCCGGGCTGGGCAGAGTGACCTGGCGGGTTACG
TACGCCACAGTTCCAAACACACATGCCAGCTCCTCTCTGAGGCGACTCTCCTGTTTGGAACTAA
AAAAAAAAAAAAAAAAATTCTCTTTTTGGTGTTGGTTAAAAGGGAACACAAAACATTTAAATAA
AACTTTCCAAATATTTCTGAGGACA

hide sequence

RefSeq Acc Id:

XM_013519690 ⟹ XP_013375144

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955452	1,860,928 - 1,873,877 (+)	NCBI

Sequence:

show sequence

ATGCCCTGGCGCTTCAGAAGCTCAATACCAACGTGGCCAAGAATGTCATCATGTTCCTGGGAGA
TGACGTACAACACCAACGCGCAGGTCCCCGACAGCGCGGGCACCGCCACCGCTTACCTATGCGG
AGTGAAGGCCAATGAGGGCACCGTGGGGGTGAGCGCAGCCACCGAGCGCACCCGGTGCAACACC
ACCCAGGGCAACGAGGTCACCTCCATCCTGAGCTGGGCCAAGGACGCTGGGAAATCCGTGGGCA
TCGTGACAACCACACGGGTGAACCACGCCACCCCCAGTGCCGCCTACGCCCACTCAGCCGACCG
GGACTGGTACTCAGACAACGAGATGCCCCCGGAGGCCCTGAGCCAGGGCTGCAAGGACATCGCC
TTCCAGCTCATGCACAACATCAAGGACATCGATGTGATCATGGGGGGTGGCCGGAAGTACATGT
ACCCCAAGAACAGAACCGACGTGGAGTACAAGATGGACGAGAAGTCCAGGGGCACGAGGCTGGA
CGGCCTGAACCTCATCGACAAATGGAAGAGCTTTAAACCAAGTAACAAGCACTCGCACTTTGTC
TGGAACCGCACCGAGCTCCTGGCACTCAACCTTCACACCGTGGACTACCTCTTGGGTCTGTTTG
AGCCTGGGGACATGCAGTACGAGCTGAACAGAAACAACGAGACCGACCCTTCGCTCTCTGAGAT
GGTGGAGGTGGCCATCAAGATCCTGAAGAAGAACCCCAAAGGCTTCTTCTTGCTGGTGGAAGGA
GGCAGGATTGACCACGGACACCATGAGGGCAAAGCCAAGCAGGCGCTGCACGAGGCGGTGGAGA
TGGACCAGGCAATCGGACAGGCCGGTGCCATGACCTCTTTGAACGACACACTGACTGTGGTCAC
GGCTGACCATTCCCACGTCTTCACCTTCGGCGGATACACACCTCGGGGCAACTCTATCTTTGGT
CTGGCCCCCATGGTGAGCGACACGGACAAGAAGCCTTTCACTGCCATCCTGTACGGCAACGGGC
CTGGCTACAAGGTAGTGGATGGAGAGCGAGAAAACGTCTCCATGGTGGACTATGCTCACAACAA
CTACCAGGCCCAGTCTGCTGTGCCCCTGCGCCATGAGACGCATGGCGGAGAGGACGTGGCCGTC
TTTGCCAAGGGCCCCATGGCGCACCTGCTGCACGGCGTCCACGAGCAGAACTACATCCCGCACA
TGATGGCCTACGCAGCCTGCATCGGGGCCAACCTCGACCACTGTGCTCAGGCCGGCTCTGCGGG
CAGCCCTGCCCTGGCGCCCCTGCTGCTCCTGCTGGTGCTGAGTCCCTTGCATGTCCTCTTCTGA
GGGCTTGGGCCCAACACCTGGGAGCCCACGACAGATGGCCGGGCTCTCTCACACCGCTGCCCGC
CCTGGGCAGCCCGCACCTCAAGGGCAGGGAGGCCGAGGCCTCCAGAACCTCTGCAGCTGCCAGG
AGGGGGACCCAGGAACCAAAGTCTGCTGCCTGCCTCACTCCCCTCTGGAATCCTCCACAGGCTG
GCCTGATACCTGGCCTCTGGGCCTGGCTCCCTCCCCGCTGCCCTTTGGCCAACAGGATAGGTTC
ATCCTGGGCACTCAGAGCATAGACTGCAGGAATCCTGAAAGCATCTTATTTTTCTAGCAGATAT
ATTTCTCCACACCCAGAAGCCTCCATGGAACATTCCAGACCTGATGGACCCTCCCATCCCCTCT
CCCTCTGGAACACACTAGGCCCCACGCTCAGTCCCCCAAGCCACGCCCTGCCTGCTGTGGAGAC
CGCCTCTCCTCGGCCTAGGAGTCTCTTGCCCACTCCAAGGGTCCTGCGGCTCCCAGGAAGCCAC
CTCCTAGGCCTGGCTGCCCACCAGGGCGGCCGGGCTGGGCAGAGTGACCTGGCGGGTTACGTAC
GCCACAGTTCCAAACACACATGCCAGCTCCTCTCTGAGGCGACTCTCCTGTTTGGAACTAAAAA
AAAAAAAAAAAAAATTCTCTTTTTGGTGTTGGTTAAAAGGGAACACAAAACATTTAAATAAAAC
TTTCCAAATATTTCTGAGGACA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013375142	(Get FASTA)	NCBI Sequence Viewer
	XP_013375143	(Get FASTA)	NCBI Sequence Viewer
	XP_013375144	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000010965.1
	ENSCLAP00000010966
	ENSCLAP00000010966.1

RefSeq Acc Id:	XP_013375142 ⟸ XM_013519688
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2V6H3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MISPFLVLAIGTCLTNSLVPEKEKDPSYWRKQAQATLKNALALQKLNTNVAKNVIMFLGDGMGV STVTAARILKGQLHHNPGEETMLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTV GVSAATERTRCNTTQGNEVTSILSWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEM PPEALSQGCKDIAFQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYKMDEKSRGTRLDGLNLIDKW KSFKPSNKHSHFVWNRTELLALNLHTVDYLLGLFEPGDMQYELNRNNETDPSLSEMVEVAIKIL KKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGQAGAMTSLNDTLTVVTADHSHVFT FGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVP LRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHMMAYAACIGANLDHCAQAGSAGSPALAPLL LLLVLSPLHVLF hide sequence

RefSeq Acc Id:	XP_013375143 ⟸ XM_013519689
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2V6H3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MISPFLVLAIGTCLTNSLVPEKEKDPSYWRKQAQATLKNALALQKLNTNVAKNVIMFLGDGMGV STVTAARILKGQLHHNPGEETMLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTV GVSAATERTRCNTTQGNEVTSILSWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEM PPEALSQGCKDIAFQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYKMDEKSRGTRLDGLNLIDKW KSFKPSNKHSHFVWNRTELLALNLHTVDYLLGLFEPGDMQYELNRNNETDPSLSEMVEVAIKIL KKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGQAGAMTSLNDTLTVVTADHSHVFT FGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVP LRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHMMAYAACIGANLDHCAQAGSAGSPALAPLL LLLVLSPLHVLF hide sequence

RefSeq Acc Id:

XP_013375144 ⟸ XM_013519690

- Peptide Label:

isoform X2

- Sequence:

show sequence

MPWRFRSSIPTWPRMSSCSWEMTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATERTRCNT
TQGNEVTSILSWAKDAGKSVGIVTTTRVNHATPSAAYAHSADRDWYSDNEMPPEALSQGCKDIA
FQLMHNIKDIDVIMGGGRKYMYPKNRTDVEYKMDEKSRGTRLDGLNLIDKWKSFKPSNKHSHFV
WNRTELLALNLHTVDYLLGLFEPGDMQYELNRNNETDPSLSEMVEVAIKILKKNPKGFFLLVEG
GRIDHGHHEGKAKQALHEAVEMDQAIGQAGAMTSLNDTLTVVTADHSHVFTFGGYTPRGNSIFG
LAPMVSDTDKKPFTAILYGNGPGYKVVDGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAV
FAKGPMAHLLHGVHEQNYIPHMMAYAACIGANLDHCAQAGSAGSPALAPLLLLLVLSPLHVLF

hide sequence

Ensembl Acc Id:

ENSCLAP00000010965 ⟸ ENSCLAT00000011100

Ensembl Acc Id:

ENSCLAP00000010966 ⟸ ENSCLAT00000011101

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000007567	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000011100.1	UniProtKB/TrEMBL
	ENSCLAT00000011101	ENTREZGENE
	ENSCLAT00000011101.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.720.10	UniProtKB/TrEMBL
InterPro	Alkaline_phosphatase	UniProtKB/TrEMBL
	Alkaline_phosphatase_AS	UniProtKB/TrEMBL
	Alkaline_phosphatase_core_sf	UniProtKB/TrEMBL
NCBI Gene	Alpl	ENTREZGENE
PANTHER	ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME	UniProtKB/TrEMBL
	PTHR11596	UniProtKB/TrEMBL
Pfam	Alk_phosphatase	UniProtKB/TrEMBL
PRINTS	ALKPHPHTASE	UniProtKB/TrEMBL
PROSITE	ALKALINE_PHOSPHATASE	UniProtKB/TrEMBL
SMART	alkPPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53649	UniProtKB/TrEMBL
UniProt	A0A8C2V6H3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-08-14	Alpl	alkaline phosphatase, biomineralization associated		alkaline phosphatase, liver/bone/kidney	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB