Furin (furin, paired basic amino acid cleaving enzyme) - Rat Genome Database

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Gene: Furin (furin, paired basic amino acid cleaving enzyme) Chinchilla lanigera
Analyze
Symbol: Furin
Name: furin, paired basic amino acid cleaving enzyme
RGD ID: 8807522
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); nerve growth factor binding (ortholog); peptidase activity (ortholog); INVOLVED IN aging (ortholog); blastocyst formation (ortholog); dibasic protein processing (ortholog); PARTICIPATES IN glypican signaling pathway; hypoxia inducible factor pathway; Notch signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); arteriosclerosis (ortholog); Bloom syndrome (ortholog); FOUND IN cell surface (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: furin (paired basic amino acid cleaving enzyme)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541614,936,546 - 14,949,252 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541614,915,031 - 14,947,634 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Furin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541614,936,546 - 14,949,252 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541614,915,031 - 14,947,634 (+)NCBIChiLan1.0ChiLan1.0
FURIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1590,868,588 - 90,883,564 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1590,868,588 - 90,883,458 (+)EnsemblGRCh38hg38GRCh38
GRCh381590,868,588 - 90,883,457 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371591,411,818 - 91,426,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361589,212,889 - 89,227,691 (+)NCBINCBI36hg18NCBI36
Build 341589,212,888 - 89,227,691NCBI
Celera1567,820,515 - 67,835,658 (+)NCBI
Cytogenetic Map15q26.1NCBI
HuRef1567,523,022 - 67,538,192 (+)NCBIHuRef
CHM1_11591,253,391 - 91,268,262 (+)NCBICHM1_1
Furin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39780,038,942 - 80,055,188 (-)NCBIGRCm39mm39
GRCm39 Ensembl780,038,333 - 80,055,184 (-)Ensembl
GRCm38780,389,194 - 80,405,441 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl780,388,585 - 80,405,436 (-)EnsemblGRCm38mm10GRCm38
MGSCv37787,534,080 - 87,550,317 (-)NCBIGRCm37mm9NCBIm37
MGSCv36780,262,709 - 80,276,275 (-)NCBImm8
Celera777,789,167 - 77,805,351 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.65NCBI
Furin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21134,348,142 - 134,361,182 (-)NCBI
Rnor_6.0 Ensembl1142,185,094 - 142,197,182 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01142,185,092 - 142,198,167 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01143,137,721 - 143,153,628 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41136,209,969 - 136,222,057 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11136,288,374 - 136,300,463NCBI
Celera1126,407,744 - 126,419,832 (-)NCBICelera
RH 3.4 Map11074.0RGD
Cytogenetic Map1q31NCBI
FURIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11588,759,729 - 88,774,023 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1588,763,269 - 88,774,023 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01569,560,774 - 69,576,007 (+)NCBIMhudiblu_PPA_v0panPan3
FURIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1353,357,491 - 53,368,285 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl353,358,045 - 53,365,423 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,995,115 - 56,006,746 (-)NCBI
ROS_Cfam_1.0353,773,528 - 53,785,153 (-)NCBI
UMICH_Zoey_3.1353,292,643 - 53,304,269 (-)NCBI
UNSW_CanFamBas_1.0353,503,862 - 53,515,505 (-)NCBI
UU_Cfam_GSD_1.0353,844,352 - 53,855,974 (-)NCBI
Furin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640130,182,463 - 130,198,421 (+)NCBI
SpeTri2.0NW_00493648316,136,099 - 16,147,945 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FURIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl753,460,017 - 53,472,790 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1753,455,634 - 53,472,791 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2758,486,815 - 58,503,979 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FURIN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1298,980,367 - 8,992,257 (-)NCBI
ChlSab1.1 Ensembl298,979,720 - 8,988,235 (-)Ensembl
Vero_WHO_p1.0NW_02366605937,732,423 - 37,745,148 (+)NCBI
Furin
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476817,372,754 - 17,387,732 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000016369   ⟹   ENSCLAP00000016205
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541614,936,546 - 14,949,252 (+)Ensembl
RefSeq Acc Id: XM_005381508   ⟹   XP_005381565
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541614,915,032 - 14,947,634 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512499   ⟹   XP_013367953
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541614,915,031 - 14,947,634 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512500   ⟹   XP_013367954
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541614,933,051 - 14,947,634 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013512501   ⟹   XP_013367955
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541614,937,037 - 14,947,634 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005381565 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367953 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367954 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367955 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005381565   ⟸   XM_005381508
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013367953   ⟸   XM_013512499
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013367954   ⟸   XM_013512500
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013367955   ⟸   XM_013512501
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000016205   ⟸   ENSCLAT00000016369


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011148 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000016205 ENTREZGENE
Ensembl Transcript ENSCLAT00000016369 ENTREZGENE
NCBI Gene Furin ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Furin  furin, paired basic amino acid cleaving enzyme    furin (paired basic amino acid cleaving enzyme)  Symbol and/or name change 5135510 APPROVED