Ints1 (integrator complex subunit 1) - Rat Genome Database

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Gene: Ints1 (integrator complex subunit 1) Chinchilla lanigera
Analyze
Symbol: Ints1
Name: integrator complex subunit 1
RGD ID: 8797004
Description: INVOLVED IN blastocyst growth (ortholog); embryo implantation (ortholog); inner cell mass cell proliferation (ortholog); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); genetic disease (ortholog); neurodevelopmental disorder with cataracts, poor growth, and dysmorphic facies (ortholog); FOUND IN integrator complex (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554609,116,891 - 9,143,120 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554609,116,650 - 9,149,470 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ints1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554609,116,891 - 9,143,120 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554609,116,650 - 9,149,470 (-)NCBIChiLan1.0ChiLan1.0
INTS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3871,470,277 - 1,504,389 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl71,470,277 - 1,504,389 (-)EnsemblGRCh38hg38GRCh38
GRCh3771,509,913 - 1,544,025 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3671,476,439 - 1,513,199 (-)NCBINCBI36Build 36hg18NCBI36
Celera71,477,287 - 1,511,447 (-)NCBICelera
Cytogenetic Map7p22.3NCBI
HuRef71,430,650 - 1,464,808 (-)NCBIHuRef
CHM1_171,509,565 - 1,543,671 (-)NCBICHM1_1
T2T-CHM13v2.071,582,409 - 1,619,912 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v271,562,263 - 1,596,426 (-)NCBI
Ints1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395139,737,037 - 139,761,455 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5139,737,037 - 139,761,429 (-)EnsemblGRCm39 Ensembl
GRCm385139,751,282 - 139,775,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5139,751,282 - 139,775,674 (-)EnsemblGRCm38mm10GRCm38
MGSCv375140,227,236 - 140,251,632 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365140,003,757 - 140,028,127 (-)NCBIMGSCv36mm8
Celera5136,806,422 - 136,830,799 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map578.8NCBI
Ints1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81219,975,166 - 19,999,893 (+)NCBIGRCr8
mRatBN7.21214,861,312 - 14,886,048 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1214,861,318 - 14,886,037 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01216,950,704 - 16,974,896 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1218,074,033 - 18,082,197 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01220,063,577 - 20,071,720 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01218,941,392 - 18,965,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41215,339,114 - 15,364,370 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11215,353,150 - 15,394,295 (+)NCBI
Celera1216,620,196 - 16,644,819 (+)NCBICelera
Cytogenetic Map12q11NCBI
INTS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v266,420,370 - 6,454,596 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1754,745,070 - 54,779,296 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v071,719,254 - 1,753,150 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.171,838,001 - 1,871,974 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl71,838,302 - 1,871,554 (-)Ensemblpanpan1.1panPan2
INTS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1615,453,491 - 15,483,240 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl615,447,391 - 15,483,239 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha616,921,168 - 16,950,886 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0615,579,451 - 15,609,172 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl615,579,248 - 15,609,165 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1615,382,213 - 15,411,928 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0615,309,000 - 15,338,719 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0615,596,044 - 15,625,763 (+)NCBIUU_Cfam_GSD_1.0
Ints1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344143,383,776 - 143,412,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367541,597,575 - 1,626,398 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367541,597,574 - 1,626,578 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INTS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3979,405 - 1,005,527 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13979,403 - 1,005,584 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.231,094,038 - 1,120,192 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INTS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12820,098,155 - 20,132,683 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2820,098,586 - 20,132,859 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660901,581,188 - 1,618,582 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ints1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474026,956,688 - 26,983,394 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474026,952,076 - 26,983,595 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000008443   ⟹   ENSCLAP00000008316
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554609,116,891 - 9,143,120 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000008444   ⟹   ENSCLAP00000008317
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554609,116,891 - 9,143,120 (-)Ensembl
RefSeq Acc Id: XM_013521197   ⟹   XP_013376651
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554609,116,650 - 9,143,394 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521198   ⟹   XP_013376652
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554609,116,650 - 9,143,398 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521199   ⟹   XP_013376653
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554609,116,650 - 9,143,444 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521200   ⟹   XP_013376654
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554609,116,650 - 9,149,470 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521201   ⟹   XP_013376655
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554609,116,650 - 9,143,394 (-)NCBI
Sequence:
RefSeq Acc Id: XP_013376654   ⟸   XM_013521200
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YLX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376653   ⟸   XM_013521199
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YLX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376652   ⟸   XM_013521198
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YLX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376655   ⟸   XM_013521201
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YLX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376651   ⟸   XM_013521197
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YLX3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000008316   ⟸   ENSCLAT00000008443
Ensembl Acc Id: ENSCLAP00000008317   ⟸   ENSCLAT00000008444
Protein Domains
Integrator complex subunit 1 INTS2-binding   Integrator complex subunit 1 R3   Integrator complex subunit 1 R4   Integrator complex subunit 1 RPB2-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005829 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008443 ENTREZGENE
  ENSCLAT00000008443.1 UniProtKB/TrEMBL
  ENSCLAT00000008444.1 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  DUF3677 UniProtKB/TrEMBL
  INT1_R3 UniProtKB/TrEMBL
  INTS1 UniProtKB/TrEMBL
  INTS1_INTS2-bd UniProtKB/TrEMBL
  INTS1_R4 UniProtKB/TrEMBL
NCBI Gene Ints1 ENTREZGENE
PANTHER INTEGRATOR COMPLEX SUBUNIT 1 UniProtKB/TrEMBL
  PTHR21224 UniProtKB/TrEMBL
Pfam DUF3677 UniProtKB/TrEMBL
  INT1_R3 UniProtKB/TrEMBL
  INTS1_INTS2-bd UniProtKB/TrEMBL
  INTS1_R4 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C2YLX2_CHILA UniProtKB/TrEMBL
  A0A8C2YLX3 ENTREZGENE, UniProtKB/TrEMBL