Ppargc1b (PPARG coactivator 1 beta) - Rat Genome Database

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Gene: Ppargc1b (PPARG coactivator 1 beta) Chinchilla lanigera
Analyze
Symbol: Ppargc1b
Name: PPARG coactivator 1 beta
RGD ID: 8794290
Description: ENCODES a protein that exhibits AF-2 domain binding (ortholog); nuclear estrogen receptor binding (ortholog); nuclear receptor coactivator activity (ortholog); INVOLVED IN actin filament organization (ortholog); bone trabecula formation (ortholog); cellular response to reactive oxygen species (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cytosol (ortholog); mediator complex (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma, coactivator 1 beta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554154,644,998 - 4,757,093 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554154,638,057 - 4,756,885 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
mediator complex  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ppargc1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554154,644,998 - 4,757,093 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554154,638,057 - 4,756,885 (-)NCBIChiLan1.0ChiLan1.0
PPARGC1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385149,730,310 - 149,857,959 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5149,730,298 - 149,855,022 (+)EnsemblGRCh38hg38GRCh38
GRCh375149,109,873 - 149,234,585 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365149,090,057 - 149,207,474 (+)NCBINCBI36Build 36hg18NCBI36
Build 345149,090,056 - 149,207,460NCBI
Celera5145,191,258 - 145,315,947 (+)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5144,256,984 - 144,381,544 (+)NCBIHuRef
CHM1_15148,542,243 - 148,667,243 (+)NCBICHM1_1
T2T-CHM13v2.05150,266,870 - 150,394,600 (+)NCBIT2T-CHM13v2.0
Ppargc1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391861,424,516 - 61,533,846 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1861,431,207 - 61,533,502 (-)EnsemblGRCm39 Ensembl
GRCm381861,291,445 - 61,400,756 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1861,298,136 - 61,400,431 (-)EnsemblGRCm38mm10GRCm38
MGSCv371861,457,790 - 61,560,085 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361861,423,505 - 61,525,800 (-)NCBIMGSCv36mm8
Celera1862,581,981 - 62,683,996 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.41NCBI
Ppargc1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81857,029,264 - 57,131,466 (-)NCBIGRCr8
mRatBN7.21854,758,891 - 54,861,103 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1854,758,902 - 54,861,194 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1856,852,399 - 56,954,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01857,567,002 - 57,669,290 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01855,382,768 - 55,484,982 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01856,626,725 - 56,650,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1856,626,712 - 56,728,968 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01855,857,439 - 55,880,661 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41857,277,749 - 57,301,024 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11857,349,991 - 57,451,796 (-)NCBI
Celera1852,911,177 - 52,934,708 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
PPARGC1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24144,955,386 - 145,119,813 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15143,098,132 - 143,223,525 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05145,154,517 - 145,315,567 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15151,172,020 - 151,286,285 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5151,203,088 - 151,278,837 (+)Ensemblpanpan1.1panPan2
PPARGC1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1459,167,041 - 59,278,977 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl459,174,604 - 59,279,464 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha458,935,873 - 59,044,751 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0459,651,179 - 59,761,207 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl459,651,182 - 59,761,176 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1459,439,467 - 59,548,290 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0459,553,927 - 59,662,788 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0460,085,118 - 60,194,024 (-)NCBIUU_Cfam_GSD_1.0
Ppargc1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213143,518,121 - 143,624,571 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365045,099,470 - 5,198,584 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365045,099,334 - 5,198,279 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPARGC1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2150,823,373 - 150,919,376 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12150,823,338 - 150,924,871 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22157,649,522 - 157,739,519 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPARGC1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12352,337,802 - 52,462,553 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2352,428,052 - 52,455,089 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603425,255,708 - 25,379,965 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppargc1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247749,056,322 - 9,174,388 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247749,056,138 - 9,178,645 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022729   ⟹   ENSCLAP00000022522
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554154,644,998 - 4,757,093 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000022730   ⟹   ENSCLAP00000022523
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554154,644,998 - 4,757,093 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000022731   ⟹   ENSCLAP00000022524
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554154,644,998 - 4,682,803 (-)Ensembl
RefSeq Acc Id: XM_005380593   ⟹   XP_005380650
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554154,638,057 - 4,756,879 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512327   ⟹   XP_013367781
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554154,638,057 - 4,756,885 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013512328   ⟹   XP_013367782
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554154,638,057 - 4,756,882 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005380650 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367781 (Get FASTA)   NCBI Sequence Viewer  
  XP_013367782 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000022522
  ENSCLAP00000022522.1
  ENSCLAP00000022523.1
  ENSCLAP00000022524.1
Reference Protein Sequences
RefSeq Acc Id: XP_005380650   ⟸   XM_005380593
- Peptide Label: isoform X2
- UniProtKB: A0A8C2W0P1 (UniProtKB/TrEMBL),   A0A8C2W5F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367781   ⟸   XM_013512327
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W5F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013367782   ⟸   XM_013512328
- Peptide Label: isoform X3
- UniProtKB: A0A8C2W5F7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000022522   ⟸   ENSCLAT00000022729
RefSeq Acc Id: ENSCLAP00000022524   ⟸   ENSCLAT00000022731
RefSeq Acc Id: ENSCLAP00000022523   ⟸   ENSCLAT00000022730
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015452 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022729 ENTREZGENE
  ENSCLAT00000022729.1 UniProtKB/TrEMBL
  ENSCLAT00000022730.1 UniProtKB/TrEMBL
  ENSCLAT00000022731.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PGC-1 UniProtKB/TrEMBL
  PPARGC1B_RRM UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene Ppargc1b ENTREZGENE
PANTHER PTHR15528 UniProtKB/TrEMBL
  PTHR15528:SF12 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8C2W0P1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2W335_CHILA UniProtKB/TrEMBL
  A0A8C2W5F7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Ppargc1b  PPARG coactivator 1 beta    peroxisome proliferator-activated receptor gamma, coactivator 1 beta  Symbol and/or name change 5135510 APPROVED