Mex3c (mex-3 RNA binding family member C) - Rat Genome Database

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Gene: Mex3c (mex-3 RNA binding family member C) Chinchilla lanigera
Analyze
Symbol: Mex3c
Name: mex-3 RNA binding family member C
RGD ID: 8793538
Description: ENCODES a protein that exhibits RNA binding (ortholog); ubiquitin protein ligase activity (ortholog); INVOLVED IN chondrocyte hypertrophy (ortholog); energy homeostasis (ortholog); regulation of fat cell differentiation (ortholog); ASSOCIATED WITH atrial fibrillation (ortholog); genetic disease (ortholog); intellectual disability (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mex-3 homolog C; RNA-binding E3 ubiquitin-protein ligase MEX3C
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540236,047,856 - 36,065,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540236,049,461 - 36,065,765 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mex3c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540236,047,856 - 36,065,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540236,049,461 - 36,065,765 (-)NCBIChiLan1.0ChiLan1.0
MEX3C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381851,174,550 - 51,197,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1851,174,550 - 51,218,333 (-)EnsemblGRCh38hg38GRCh38
GRCh371848,700,920 - 48,724,051 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361846,954,918 - 46,977,688 (-)NCBINCBI36Build 36hg18NCBI36
Build 341846,954,919 - 46,977,380NCBI
Celera1845,557,653 - 45,580,784 (-)NCBICelera
Cytogenetic Map18q21.2NCBI
HuRef1845,556,322 - 45,579,835 (-)NCBIHuRef
CHM1_11848,696,271 - 48,719,389 (-)NCBICHM1_1
T2T-CHM13v2.01851,376,318 - 51,399,436 (-)NCBIT2T-CHM13v2.0
Mex3c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391873,705,710 - 73,725,649 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1873,706,115 - 73,725,646 (+)EnsemblGRCm39 Ensembl
GRCm381873,572,637 - 73,592,578 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1873,573,044 - 73,592,575 (+)EnsemblGRCm38mm10GRCm38
MGSCv371873,732,359 - 73,752,232 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361873,698,157 - 73,700,208 (+)NCBIMGSCv36mm8
Celera1874,818,491 - 74,838,159 (+)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1849.29NCBI
Mex3c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81869,442,850 - 69,463,843 (+)NCBIGRCr8
mRatBN7.21867,167,600 - 67,188,595 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1867,166,718 - 67,188,595 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1869,275,700 - 69,296,678 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01869,950,428 - 69,971,396 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01867,815,662 - 67,836,650 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01869,549,937 - 69,571,736 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1869,549,937 - 69,571,736 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01868,674,091 - 68,717,243 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41870,355,267 - 70,376,424 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11870,428,370 - 70,449,630 (+)NCBI
Celera1865,169,728 - 65,190,911 (+)NCBICelera
Cytogenetic Map18q12.2NCBI
MEX3C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21768,693,635 - 68,716,861 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11854,386,240 - 54,411,080 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01844,546,129 - 44,569,580 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11847,891,070 - 47,913,475 (-)NCBIpanpan1.1PanPan1.1panPan2
MEX3C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1123,818,790 - 23,838,106 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl123,818,099 - 23,836,297 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha124,805,803 - 24,825,631 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0123,709,603 - 23,730,449 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1123,770,888 - 23,790,686 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0123,657,154 - 23,677,248 (+)NCBIUNSW_CanFamBas_1.0
Mex3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494436,919,805 - 36,962,760 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649712,178,344 - 12,201,797 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649712,178,350 - 12,201,795 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEX3C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1100,676,660 - 100,699,403 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11100,678,452 - 100,699,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21110,611,812 - 110,633,611 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MEX3C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11829,788,281 - 29,811,274 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1829,788,642 - 29,809,477 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660503,916,172 - 3,939,164 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mex3c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477814,685,172 - 14,701,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000010188   ⟹   ENSCLAP00000010058
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540236,047,856 - 36,065,771 (-)Ensembl
RefSeq Acc Id: XM_005372940   ⟹   XP_005372997
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540236,049,461 - 36,065,765 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005372997 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000010058
  ENSCLAP00000010058.1
Reference Protein Sequences
RefSeq Acc Id: XP_005372997   ⟸   XM_005372940
- Sequence:
RefSeq Acc Id: ENSCLAP00000010058   ⟸   ENSCLAT00000010188
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006969 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010188 ENTREZGENE
  ENSCLAT00000010188.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro KH-I_MEX3_rpt1 UniProtKB/TrEMBL
  KH-I_MEX3_rpt2 UniProtKB/TrEMBL
  KH_dom UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  MEX3 UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Mex3c ENTREZGENE
PANTHER RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX3C UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/TrEMBL
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
  SM00322 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54791 UniProtKB/TrEMBL
UniProt A0A8C2V4Y4_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Mex3c  mex-3 RNA binding family member C    mex-3 homolog C (C. elegans)  Symbol and/or name change 5135510 APPROVED