Pcolce2 (procollagen C-endopeptidase enhancer 2)

Gene: Pcolce2 (procollagen C-endopeptidase enhancer 2) Chinchilla lanigera

Analyze

Symbol:

Pcolce2

Name:

procollagen C-endopeptidase enhancer 2

RGD ID:

8787425

Description:

ENCODES a protein that exhibits collagen binding (ortholog); heparin binding (ortholog); peptidase activator activity (ortholog); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); genetic disease (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955508	3,058,523 - 3,132,222 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955508	3,058,789 - 3,132,050 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leukemia inhibitory factor (ISO)

Molecular Function

collagen binding (ISO)

heparin binding (ISO)

peptidase activator activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Pcolce2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955508	3,058,523 - 3,132,222 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955508	3,058,789 - 3,132,050 (+)	NCBI	ChiLan1.0	ChiLan1.0

PCOLCE2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	142,817,874 - 142,889,083 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	142,815,922 - 142,889,206 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	142,536,716 - 142,607,925 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	144,019,401 - 144,090,624 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	144,019,409 - 144,090,632	NCBI
Celera	3	140,960,205 - 141,031,522 (-)	NCBI		Celera
Cytogenetic Map	3	q23	NCBI
HuRef	3	139,909,421 - 139,980,794 (-)	NCBI		HuRef
CHM1_1	3	142,499,699 - 142,571,046 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	145,565,117 - 145,636,326 (-)	NCBI		T2T-CHM13v2.0

Pcolce2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	95,519,681 - 95,577,604 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	95,519,654 - 95,580,149 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	95,637,628 - 95,695,551 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	95,637,601 - 95,698,096 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	95,538,047 - 95,595,970 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	95,446,980 - 95,504,903 (+)	NCBI		MGSCv36	mm8
Celera	9	95,204,827 - 95,262,682 (+)	NCBI		Celera
Cytogenetic Map	9	E3.3	NCBI
cM Map	9	50.18	NCBI

PCOLCE2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	105,073,086 - 105,130,725 (+)	NCBI		GRCr8
mRatBN7.2	8	96,193,461 - 96,251,116 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	96,193,461 - 96,251,114 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	101,865,338 - 101,922,789 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	100,064,593 - 100,122,044 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	97,903,532 - 97,960,986 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	103,459,219 - 103,484,557 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	103,459,161 - 103,484,535 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	102,910,334 - 102,934,915 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	8	95,642,683 - 95,698,669 (+)	NCBI		Celera
Cytogenetic Map	8	q31	NCBI

PCOLCE2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	140,728,575 - 140,800,807 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	140,733,307 - 140,805,486 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	139,851,001 - 139,922,955 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	147,442,307 - 147,514,234 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	147,442,307 - 147,514,234 (-)	Ensembl	panpan1.1		panPan2

PCOLCE2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	38,424,408 - 38,486,800 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	38,426,216 - 38,487,252 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	38,350,484 - 38,412,732 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	38,956,476 - 39,018,760 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	38,956,478 - 39,018,754 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	38,638,362 - 38,702,463 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	38,714,782 - 38,776,983 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	38,959,175 - 39,021,451 (-)	NCBI		UU_Cfam_GSD_1.0

Pcolce2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	77,687,130 - 77,745,472 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936540	4,426,921 - 4,485,255 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936540	4,426,913 - 4,485,251 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PCOLCE2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	83,507,611 - 83,592,764 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	83,507,607 - 83,592,929 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	91,282,165 - 91,367,177 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCOLCE2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	47,743,530 - 47,815,448 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	47,743,589 - 47,817,429 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	20,677,719 - 20,749,565 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pcolce2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	19,399,941 - 19,486,757 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	19,400,022 - 19,486,499 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013506286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01065804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01065805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01081589	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000002242 ⟹ ENSCLAP00000002196

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955508	3,058,523 - 3,132,222 (+)	Ensembl

RefSeq Acc Id:

XM_013506286 ⟹ XP_013361740

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955508	3,058,789 - 3,132,050 (+)	NCBI

Sequence:

show sequence

CGGAGACAGAGGGGGAGCCCCAAGGATTCCAGCAAACACCAAGCGCTGATACGTTTTATTTGCA
AGCGGCCCCGCAAGCAGACCGCCGCCTGGGGACCGCGCCCGCCGGGCTCCCGCGGGGTGAGCCG
CCCGCCCGCCCAGGAGAGGAGGCGGCCCCGGCGTCGGAGCCGCCCTCCTCGGCCGAGAACAAAC
GGGACATTCAGCGGGGCGTGCGGCCGCCGCAGCGCCTCCGCGGAGGAACCCCAGGTCGAGGCGG
ACGCGCCGCCGCCGCCGCACAGCGCCCCCGCCCGCCGCGCCGCGCGCAGACCGAGCGGAGCGCG
GAGGACCGAGGCGCCGCGGCCGCCGGGGGCGGAGCCCTGCGCGTGCTCCCAGCCATGAGGGCCG
CGCTGTGCCTGCTGCTGGCCGCCGCCGCGCAGCTGTCCCGGCAGCAGCGCCCGGAGAGACCTGT
TTTCAGATGTGGCGGCGTTCTTACTGGAGAATCTGGATTTATTGGCAGTGAAGGTTTTCCTGGA
GTGTACCCTCCAAATAGTAAATGCACTTGGAAAATCACAGTTCCTGAGGGGAAAGTAGTCGTCC
TTAATTTCCGATTCATAGACCTTGAGAGCGACAACCTGTGCCGCTATGACTTTGTGGACGTGTA
CAATGGCCACACCAACGGCCAGCGCATGGGCCGCTTTTGCGGCACATTCCGACCTGGAGCCCTG
GTGTCCAGTGGGAACAAGATGATGGTGAAGATGATTTCCGATGCCAATACAGCAGGAAACGGCT
TCATGGCCATGTTCTCTGCCTCCGAACCCAATGAAAGAGGGGACCAGTATTGTGGAGGACGCCT
TGAAAGACCTTTGGGCTCTTTTAAAACCCCCAACTGGCCAGACCGGGATTATCCTGTAGGAGTC
ACGTGTATATGGCACATCATAGCCCCCAAAAATCAGCTTATAGAATTAAAATTTGAGAAGTTTG
ATGTAGAGCGAGATAACTACTGTCGATACGATTTCGTGGCTGTGTTCAACGGCGGAGAAGTGAA
CGATGCTCAGAGAATTGGAAAGTACTGCGGCGACAGTCCTCCTGCGCCAATTGTATCCGAGAGA
AATGAACTTCTTATTCAGTTTTTATCAGACCTAAGTTTAACAGCAGATGGATTTATTGGTCACT
ACAAATTCAGGCCAAAAAAGTTGCCTCCGACTACAGCAGCGCCCATTACCACCACAAACGCGGT
CACTACAAGTTTGAAACCAACAGTGGCCCTGTGTCAGCAGAAGTGTAGACGGACGGGAACTCTG
GAGAGCAATTATTGTTCAAACAACTTTGTGTTAGTCGGCGCTGTTATCACGACCGCCATTCGGG
GTGAGAGTTTGCAGGCCACGATCTCAATCATCAACATCTACAAAGAGGGGAACCTGGCAATCCA
GCAGGCCGGCAAGAACATGAGTGCCAAGGTTACCGTGGTCTGCAGGCAGTGCCCTCTCCTCAGA
CGAGGTCTAAATTACATCATTATGGGCCAAGTGGGAGAAGACGGGCAAGGGAAGCTCATGCCAA
GTAGCTTTGTCATGATGTTCAAGACCAAGAACCAGAAGCTGCTGAATGCTTTAAAAAACAAGCA
GTGTTAACAGTGAGCTGTGTCTGTATAAGCCGCCTTCTGTTGTTGCCTTTGAAAGATCTGTCTT
CCCTAAGTAGACAAAAAAACCCGCACGCCTTAACAGGGAGCGTTCCGAAGGGCCGGAATGCTTC
TCTCTTCACACCATGTAGGTCTGTGATGTCGCTGATGCAAGTTCTGAGCCCGCACAGAGAGCAG
ACAGCTGAAAACCTGCCGACAGCTTGAGCGCAGTTTCTTTGTACATCTCTGTAAAAGGATATCT
TAGAATTGTGTGAAGACATAAAAAAGAGATTTTATAAGTGCAATATTTATAGTGATATTTGTTT
TACCTTGAAGCATTTGCTCTGAGGTGTTATATTCTTCTCTTGCATTTTTAAGTCAGAGCTTAAT
AAAATATATTTAAATGATCACATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013361740	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000002196
	ENSCLAP00000002196.1

RefSeq Acc Id:

XP_013361740 ⟸ XM_013506286

- UniProtKB:

A0A8C2URQ8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRAALCLLLAAAAQLSRQQRPERPVFRCGGVLTGESGFIGSEGFPGVYPPNSKCTWKITVPEGK
VVVLNFRFIDLESDNLCRYDFVDVYNGHTNGQRMGRFCGTFRPGALVSSGNKMMVKMISDANTA
GNGFMAMFSASEPNERGDQYCGGRLERPLGSFKTPNWPDRDYPVGVTCIWHIIAPKNQLIELKF
EKFDVERDNYCRYDFVAVFNGGEVNDAQRIGKYCGDSPPAPIVSERNELLIQFLSDLSLTADGF
IGHYKFRPKKLPPTTAAPITTTNAVTTSLKPTVALCQQKCRRTGTLESNYCSNNFVLVGAVITT
AIRGESLQATISIINIYKEGNLAIQQAGKNMSAKVTVVCRQCPLLRRGLNYIIMGQVGEDGQGK
LMPSSFVMMFKTKNQKLLNALKNKQC

hide sequence

RefSeq Acc Id:

ENSCLAP00000002196 ⟸ ENSCLAT00000002242

Protein Domains

CUB NTR

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000001585	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000002242	ENTREZGENE
	ENSCLAT00000002242.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.120	UniProtKB/TrEMBL
	2.60.120.290	UniProtKB/TrEMBL
InterPro	CUB_dom	UniProtKB/TrEMBL
	Netrin_domain	UniProtKB/TrEMBL
	Netrin_module_non-TIMP	UniProtKB/TrEMBL
	NTR_PCOLCE	UniProtKB/TrEMBL
	Sperma_CUB_dom_sf	UniProtKB/TrEMBL
	TIMP-like_OB-fold	UniProtKB/TrEMBL
NCBI Gene	Pcolce2	ENTREZGENE
PANTHER	OVOCHYMASE-RELATED	UniProtKB/TrEMBL
	PROCOLLAGEN C-ENDOPEPTIDASE ENHANCER 2	UniProtKB/TrEMBL
Pfam	CUB	UniProtKB/TrEMBL
	NTR	UniProtKB/TrEMBL
PROSITE	CUB	UniProtKB/TrEMBL
	NTR	UniProtKB/TrEMBL
SMART	C345C	UniProtKB/TrEMBL
	CUB	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49854	UniProtKB/TrEMBL
	SSF50242	UniProtKB/TrEMBL
UniProt	A0A8C2URQ8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD