Tal1 (TAL bHLH transcription factor 1, erythroid differentiation factor) - Rat Genome Database

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Gene: Tal1 (TAL bHLH transcription factor 1, erythroid differentiation factor) Chinchilla lanigera
Analyze
Symbol: Tal1
Name: TAL bHLH transcription factor 1, erythroid differentiation factor
RGD ID: 8786141
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN angiogenesis (ortholog); astrocyte fate commitment (ortholog); basophil differentiation (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); genetic disease (ortholog); T-cell acute lymphoblastic leukemia (ortholog); FOUND IN chromatin (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: T-cell acute lymphocytic leukemia 1; T-cell acute lymphocytic leukemia protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546411,310,628 - 11,315,924 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546411,304,611 - 11,317,420 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tal1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546411,310,628 - 11,315,924 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546411,304,611 - 11,317,420 (+)NCBIChiLan1.0ChiLan1.0
TAL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38147,216,290 - 47,232,335 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl147,216,290 - 47,232,225 (-)EnsemblGRCh38hg38GRCh38
GRCh37147,681,962 - 47,698,007 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36147,454,551 - 47,468,030 (-)NCBINCBI36Build 36hg18NCBI36
Build 34147,393,983 - 47,407,463NCBI
Celera145,968,230 - 45,981,708 (-)NCBICelera
Cytogenetic Map1p33NCBI
HuRef145,798,600 - 45,812,074 (-)NCBIHuRef
CHM1_1147,798,845 - 47,812,319 (-)NCBICHM1_1
T2T-CHM13v2.0147,094,699 - 47,110,742 (-)NCBIT2T-CHM13v2.0
Tal1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394114,913,623 - 114,928,952 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4114,913,623 - 114,928,952 (+)EnsemblGRCm39 Ensembl
GRCm384115,056,426 - 115,071,755 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4115,056,426 - 115,071,755 (+)EnsemblGRCm38mm10GRCm38
MGSCv374114,732,132 - 114,744,360 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364114,557,459 - 114,569,687 (+)NCBIMGSCv36mm8
Celera4113,806,727 - 113,818,916 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map452.73NCBI
Tal1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85133,823,093 - 133,837,737 (+)NCBIGRCr8
mRatBN7.25128,586,776 - 128,600,976 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5128,587,701 - 128,600,976 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5131,270,143 - 131,283,468 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05132,999,788 - 133,013,121 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,021,481 - 133,034,804 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05133,864,401 - 133,878,604 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5133,864,798 - 133,878,830 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05137,655,978 - 137,670,144 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45135,430,985 - 135,444,692 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15135,438,330 - 135,447,104 (+)NCBI
Celera5127,232,703 - 127,245,971 (+)NCBICelera
Cytogenetic Map5q35NCBI
TAL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21179,570,869 - 179,586,982 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11178,712,653 - 178,728,777 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0146,524,484 - 46,540,595 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1148,039,155 - 48,054,021 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl148,042,594 - 48,048,622 (-)Ensemblpanpan1.1panPan2
TAL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11513,446,752 - 13,462,038 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1513,449,481 - 13,462,047 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1513,598,407 - 13,614,022 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01513,595,386 - 13,611,008 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1513,598,590 - 13,611,010 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11513,395,087 - 13,410,685 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01513,463,077 - 13,478,696 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01513,532,579 - 13,548,206 (+)NCBIUU_Cfam_GSD_1.0
Tal1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505862,223,080 - 62,238,124 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647428,047,808 - 28,056,065 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647428,049,326 - 28,061,495 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6164,283,366 - 164,295,290 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16164,282,242 - 164,297,636 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26151,830,187 - 151,846,169 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12085,681,247 - 85,697,887 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2085,688,155 - 85,694,829 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603331,381,681 - 31,398,704 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tal1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248595,586,977 - 5,601,460 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248595,586,489 - 5,601,225 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000010009   ⟹   ENSCLAP00000009879
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546411,310,628 - 11,315,924 (+)Ensembl
RefSeq Acc Id: XM_013521747   ⟹   XP_013377201
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546411,305,570 - 11,317,420 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013521748   ⟹   XP_013377202
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546411,305,570 - 11,317,420 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013521749   ⟹   XP_013377203
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546411,304,611 - 11,317,420 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013377201 (Get FASTA)   NCBI Sequence Viewer  
  XP_013377202 (Get FASTA)   NCBI Sequence Viewer  
  XP_013377203 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000009879
  ENSCLAP00000009879.1
RefSeq Acc Id: XP_013377203   ⟸   XM_013521749
- Sequence:
RefSeq Acc Id: XP_013377201   ⟸   XM_013521747
- Sequence:
RefSeq Acc Id: XP_013377202   ⟸   XM_013521748
- Sequence:
RefSeq Acc Id: ENSCLAP00000009879   ⟸   ENSCLAT00000010009
Protein Domains
bHLH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010009 ENTREZGENE
  ENSCLAT00000010009.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  TAL-like UniProtKB/TrEMBL
NCBI Gene Tal1 ENTREZGENE
PANTHER PTHR13864 UniProtKB/TrEMBL
  T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 UniProtKB/TrEMBL
Pfam HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A8C2VAH3_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Tal1  TAL bHLH transcription factor 1, erythroid differentiation factor    T-cell acute lymphocytic leukemia 1  Symbol and/or name change 5135510 APPROVED