Hexb (hexosaminidase subunit beta) - Rat Genome Database

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Gene: Hexb (hexosaminidase subunit beta) Chinchilla lanigera
Analyze
Symbol: Hexb
Name: hexosaminidase subunit beta
RGD ID: 8786114
Description: ENCODES a protein that exhibits acetylglucosaminyltransferase activity (ortholog); beta-N-acetylglucosaminidase activity (ortholog); beta-N-acetylhexosaminidase activity (ortholog); INVOLVED IN astrocyte cell migration (ortholog); cellular calcium ion homeostasis (ortholog); chondroitin sulfate catabolic process (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN acrosomal vesicle (ortholog); azurophil granule (ortholog); beta-N-acetylhexosaminidase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-hexosaminidase subunit beta; hexosaminidase B (beta polypeptide)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,942,278 - 25,961,312 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,942,341 - 25,961,312 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline

Genomics

Comparative Map Data
Hexb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,942,278 - 25,961,312 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,942,341 - 25,961,312 (-)NCBIChiLan1.0ChiLan1.0
HEXB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38574,640,023 - 74,721,288 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl574,640,023 - 74,722,647 (+)EnsemblGRCh38hg38GRCh38
GRCh37573,935,848 - 74,017,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,016,767 - 74,052,869 (+)NCBINCBI36hg18NCBI36
Build 34574,016,766 - 74,052,869NCBI
Celera569,875,759 - 69,911,869 (+)NCBI
Cytogenetic Map5q13.3NCBI
HuRef569,185,979 - 69,222,054 (+)NCBIHuRef
CHM1_1573,413,670 - 73,449,974 (+)NCBICHM1_1
T2T-CHM13v2.0575,120,988 - 75,202,190 (+)NCBI
Hexb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,312,839 - 97,334,865 (-)NCBIGRCm39mm39
GRCm39 Ensembl1397,312,839 - 97,334,865 (-)Ensembl
GRCm381397,176,331 - 97,198,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1397,176,331 - 97,198,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv371397,946,286 - 97,968,312 (-)NCBIGRCm37mm9NCBIm37
MGSCv361398,277,106 - 98,298,969 (-)NCBImm8
Celera13100,809,364 - 100,830,755 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
Hexb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2228,483,997 - 28,504,165 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl228,484,012 - 28,504,223 (-)Ensembl
Rnor_6.0227,983,925 - 28,003,260 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,984,117 - 28,003,186 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0247,094,814 - 47,114,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,649,188 - 27,672,231 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1227,569,557 - 27,592,600 (-)NCBI
Celera224,525,921 - 24,545,955 (-)NCBICelera
Cytogenetic Map2q12NCBI
HEXB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1541,199,681 - 41,232,693 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl541,199,681 - 41,232,693 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0540,589,448 - 40,625,176 (-)NCBIMhudiblu_PPA_v0panPan3
HEXB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,221,809 - 57,248,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,222,186 - 57,248,417 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,199,623 - 54,228,736 (+)NCBI
ROS_Cfam_1.0257,746,022 - 57,775,171 (+)NCBI
ROS_Cfam_1.0 Ensembl257,745,874 - 57,775,170 (+)Ensembl
UMICH_Zoey_3.1254,810,104 - 54,839,238 (+)NCBI
UNSW_CanFamBas_1.0255,573,246 - 55,602,349 (+)NCBI
UU_Cfam_GSD_1.0256,470,393 - 56,499,556 (+)NCBI
Hexb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213188,915,295 - 188,940,491 (+)NCBI
SpeTri2.0NW_0049365491,918,482 - 1,943,665 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEXB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,744,627 - 83,784,759 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1283,745,263 - 83,784,762 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,331,866 - 85,371,568 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HEXB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,037,532 - 69,065,925 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl469,037,583 - 69,065,814 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604917,815,486 - 17,843,814 (+)NCBIVero_WHO_p1.0
Hexb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624924195,175 - 219,278 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624924195,406 - 219,232 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023561   ⟹   ENSCLAP00000023340
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542525,942,278 - 25,961,312 (-)Ensembl
RefSeq Acc Id: XM_005386061   ⟹   XP_005386118
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542525,942,341 - 25,961,312 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386118 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005386118   ⟸   XM_005386061
- Sequence:
RefSeq Acc Id: ENSCLAP00000023340   ⟸   ENSCLAT00000023561
Protein Domains
Glyco_hydro_20   Glycohydro_20b2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016006 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000023340 ENTREZGENE
  ENSCLAP00000023340.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023561 ENTREZGENE
  ENSCLAT00000023561.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.379.10 UniProtKB/TrEMBL
InterPro Beta_hexosaminidase_sua/sub UniProtKB/TrEMBL
  Glyco_hydro_20_cat UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/TrEMBL
  Hex-like_dom2 UniProtKB/TrEMBL
  HEX_eukaryotic_N UniProtKB/TrEMBL
NCBI Gene Hexb ENTREZGENE
PANTHER PTHR22600 UniProtKB/TrEMBL
Pfam Glyco_hydro_20 UniProtKB/TrEMBL
  Glycohydro_20b2 UniProtKB/TrEMBL
PIRSF B-hxosamndse_ab_euk UniProtKB/TrEMBL
PRINTS GLHYDRLASE20 UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/TrEMBL
  SSF55545 UniProtKB/TrEMBL
UniProt A0A8C2W543_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Hexb  hexosaminidase subunit beta    hexosaminidase B (beta polypeptide)  Symbol and/or name change 5135510 APPROVED