Mctp1 (multiple C2 and transmembrane domain containing 1) - Rat Genome Database

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Gene: Mctp1 (multiple C2 and transmembrane domain containing 1) Chinchilla lanigera
Analyze
Symbol: Mctp1
Name: multiple C2 and transmembrane domain containing 1
RGD ID: 8776549
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); INVOLVED IN negative regulation of cell migration (ortholog); negative regulation of endocytosis (ortholog); negative regulation of response to oxidative stress (ortholog); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN membrane (ortholog); recycling endosome (ortholog); synaptic vesicle membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: multiple C2 and transmembrane domain-containing protein 1; multiple C2 domains, transmembrane 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541817,229,498 - 17,745,010 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541817,229,498 - 17,746,936 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mctp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541817,229,498 - 17,745,010 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541817,229,498 - 17,746,936 (+)NCBIChiLan1.0ChiLan1.0
MCTP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38594,703,690 - 95,285,094 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl594,703,690 - 95,285,094 (-)EnsemblGRCh38hg38GRCh38
GRCh37594,039,395 - 94,620,798 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36594,068,957 - 94,646,035 (-)NCBINCBI36Build 36hg18NCBI36
Celera589,904,181 - 90,498,783 (-)NCBICelera
Cytogenetic Map5q15NCBI
HuRef589,215,571 - 89,810,232 (-)NCBIHuRef
CHM1_1593,474,921 - 94,052,972 (-)NCBICHM1_1
T2T-CHM13v2.0595,188,075 - 95,786,099 (-)NCBIT2T-CHM13v2.0
Mctp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391376,530,481 - 77,181,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1376,532,259 - 77,179,929 (+)EnsemblGRCm39 Ensembl
GRCm381376,382,362 - 77,033,284 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1376,384,535 - 77,031,810 (+)EnsemblGRCm38mm10GRCm38
MGSCv371376,522,409 - 77,171,071 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361376,850,963 - 77,495,357 (+)NCBIMGSCv36mm8
Celera1378,709,211 - 79,357,429 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.98NCBI
Mctp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr827,798,968 - 8,493,596 (+)NCBIGRCr8
mRatBN7.226,071,408 - 6,761,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl26,065,808 - 6,761,833 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx213,149,950 - 13,873,885 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0211,249,210 - 11,973,165 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.025,914,158 - 6,608,224 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.023,400,883 - 4,089,949 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl23,400,977 - 4,088,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.023,398,033 - 4,086,933 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.423,652,722 - 4,354,754 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.123,941,173 - 4,377,606 (+)NCBI
Celera22,535,961 - 3,220,251 (+)NCBICelera
Cytogenetic Map2q11NCBI
MCTP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2420,100,647 - 20,697,607 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1518,254,259 - 18,851,219 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0520,071,072 - 20,669,826 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1520,215,984 - 20,808,014 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl520,215,917 - 20,808,014 (+)Ensemblpanpan1.1panPan2
MCTP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1314,255,685 - 14,782,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl314,358,134 - 14,780,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha315,594,036 - 16,121,093 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0314,133,526 - 14,662,420 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl314,133,527 - 14,682,475 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1314,098,067 - 14,625,300 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0314,095,557 - 14,623,822 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0314,295,164 - 14,827,487 (+)NCBIUU_Cfam_GSD_1.0
Mctp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213169,864,546 - 170,367,862 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365238,050,006 - 8,553,432 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365238,050,001 - 8,553,427 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCTP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2101,384,910 - 101,920,111 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12101,384,904 - 101,920,152 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22104,928,439 - 105,217,494 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCTP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1488,581,761 - 89,174,995 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl488,585,446 - 88,967,701 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604937,226,961 - 37,820,001 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mctp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474313,405,481 - 13,919,373 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474313,401,767 - 13,919,388 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013513035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01019147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01019157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBCQ01175680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCLAT00000007147   ⟹   ENSCLAP00000007035
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541817,229,498 - 17,745,010 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000007148   ⟹   ENSCLAP00000007036
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541817,402,079 - 17,560,452 (+)Ensembl
RefSeq Acc Id: XM_013513035   ⟹   XP_013368489
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,229,498 - 17,746,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513036   ⟹   XP_013368490
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,401,931 - 17,746,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513037   ⟹   XP_013368491
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,434,428 - 17,746,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513038   ⟹   XP_013368492
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,401,931 - 17,746,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513039   ⟹   XP_013368493
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,441,901 - 17,746,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513041   ⟹   XP_013368495
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,377,329 - 17,746,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513042   ⟹   XP_013368496
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,430,468 - 17,746,936 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013513043   ⟹   XP_013368497
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541817,401,931 - 17,746,936 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013368489   ⟸   XM_013513035
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UXX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013368495   ⟸   XM_013513041
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013368490   ⟸   XM_013513036
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013368492   ⟸   XM_013513038
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013368497   ⟸   XM_013513043
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_013368496   ⟸   XM_013513042
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013368491   ⟸   XM_013513037
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013368493   ⟸   XM_013513039
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000007035   ⟸   ENSCLAT00000007147
RefSeq Acc Id: ENSCLAP00000007036   ⟸   ENSCLAT00000007148
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004952 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007147 ENTREZGENE
  ENSCLAT00000007147.1 UniProtKB/TrEMBL
  ENSCLAT00000007148.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  PRibTrfase_C UniProtKB/TrEMBL
NCBI Gene Mctp1 ENTREZGENE
PANTHER C2 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  DYSFERLIN-RELATED UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  PRT_C UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A8C2UXX5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2V0M8_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Mctp1  multiple C2 and transmembrane domain containing 1    multiple C2 domains, transmembrane 1  Symbol and/or name change 5135510 APPROVED