Septin1 (septin 1) - Rat Genome Database

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Gene: Septin1 (septin 1) Chinchilla lanigera
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Symbol: Septin1
Name: septin 1
RGD ID: 8771415
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN meiotic metaphase chromosome alignment (ortholog); spindle assembly involved in female meiosis (ortholog); ASSOCIATED WITH dilated cardiomyopathy (ortholog); FOUND IN meiotic spindle (ortholog); midbody (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Sept1; septin-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,304,472 - 7,312,185 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,304,472 - 7,309,022 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
meiotic spindle  (ISO)
midbody  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Septin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,304,472 - 7,312,185 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,304,472 - 7,309,022 (-)NCBIChiLan1.0ChiLan1.0
SEPTIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,378,135 - 30,382,815 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,378,135 - 30,395,991 (-)EnsemblGRCh38hg38GRCh38
GRCh371630,389,456 - 30,394,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,296,957 - 30,301,672 (-)NCBINCBI36Build 36hg18NCBI36
Build 341630,296,957 - 30,301,672NCBI
Celera1629,904,429 - 29,909,188 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,951,218 - 27,955,945 (-)NCBIHuRef
CHM1_11631,706,508 - 31,711,226 (-)NCBICHM1_1
T2T-CHM13v2.01630,764,338 - 30,769,019 (-)NCBIT2T-CHM13v2.0
Septin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,811,881 - 126,832,157 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,813,619 - 126,832,302 (-)EnsemblGRCm39 Ensembl
GRCm387127,212,709 - 127,232,985 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,214,447 - 127,233,130 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,357,956 - 134,361,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,005,598 - 127,009,601 (-)NCBIMGSCv36mm8
Celera7127,063,210 - 127,067,214 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.39NCBI
Septin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,263,200 - 191,267,086 (-)NCBIGRCr8
mRatBN7.21181,832,700 - 181,836,566 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,832,701 - 181,836,566 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,183,588 - 190,187,454 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,369,676 - 197,373,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01190,038,210 - 190,042,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,658,744 - 198,662,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,658,745 - 198,662,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,652,475 - 205,656,341 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,474,714 - 186,478,580 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,624,595 - 186,628,461 (-)NCBI
Celera1179,484,367 - 179,488,232 (-)NCBICelera
Cytogenetic Map1q37NCBI
SEPTIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21833,583,330 - 33,593,399 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11638,384,787 - 38,402,163 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01624,586,711 - 24,591,587 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11630,751,869 - 30,755,133 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,750,665 - 30,755,345 (-)Ensemblpanpan1.1panPan2
SEPTIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,714,929 - 17,718,972 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,715,408 - 17,719,159 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,289,544 - 19,293,553 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,846,389 - 17,850,406 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,846,585 - 17,850,402 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,646,593 - 17,650,610 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,562,034 - 17,566,041 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,877,697 - 17,881,714 (+)NCBIUU_Cfam_GSD_1.0
Septin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,749,372 - 124,762,085 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,843,820 - 12,851,032 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,847,236 - 12,852,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEPTIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,924,651 - 17,937,947 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,924,651 - 17,937,949 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,359,300 - 18,376,616 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEPTIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,055,239 - 27,059,749 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl527,055,538 - 27,059,723 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,461,126 - 2,465,801 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Septin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,550,185 - 13,553,480 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,549,862 - 13,553,557 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000015387   ⟹   ENSCLAP00000015227
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554937,304,472 - 7,312,185 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000015388   ⟹   ENSCLAP00000015228
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554937,304,681 - 7,312,185 (-)Ensembl
RefSeq Acc Id: XM_005405254   ⟹   XP_005405311
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554937,304,472 - 7,309,022 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005405255   ⟹   XP_005405312
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554937,304,472 - 7,309,021 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005405257   ⟹   XP_005405314
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554937,304,472 - 7,308,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504780   ⟹   XP_013360234
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554937,304,472 - 7,309,022 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005405311   ⟸   XM_005405254
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VGC3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005405312   ⟸   XM_005405255
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005405314   ⟸   XM_005405257
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VGE8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013360234   ⟸   XM_013504780
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCLAP00000015228   ⟸   ENSCLAT00000015388
Ensembl Acc Id: ENSCLAP00000015227   ⟸   ENSCLAT00000015387
Protein Domains
Septin-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010486 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000015387 ENTREZGENE
  ENSCLAT00000015387.1 UniProtKB/TrEMBL
  ENSCLAT00000015388 ENTREZGENE
  ENSCLAT00000015388.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro G_SEPTIN_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Septin UniProtKB/TrEMBL
NCBI Gene Sept1 ENTREZGENE
PANTHER SEPTIN UniProtKB/TrEMBL
  SEPTIN-1 UniProtKB/TrEMBL
Pfam Septin UniProtKB/TrEMBL
PIRSF Septin UniProtKB/TrEMBL
PROSITE G_SEPTIN UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C2VGC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VGE8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-09 Septin1  septin 1  Sept1    Symbol and/or name change 5135510 APPROVED