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Gene: Dhfr (dihydrofolate reductase) Chinchilla lanigera
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Symbol: Dhfr
Name: dihydrofolate reductase
RGD ID: 8768992
Description: ENCODES a protein that exhibits dihydrofolate reductase activity (ortholog); dihydrofolic acid binding (ortholog); drug binding (ortholog); INVOLVED IN axon regeneration (ortholog); dihydrofolate metabolic process (ortholog); folic acid metabolic process (ortholog); PARTICIPATES IN altered folate cycle metabolic pathway; dopa responsive dystonia pathway; folate cycle metabolic pathway; ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); autistic disorder (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : DHFR (dihydrofolate reductase)  HGNC  Alliance
Mus musculus (house mouse) : Dhfr (dihydrofolate reductase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dhfr (dihydrofolate reductase)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : DHFR (dihydrofolate reductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhfr (dihydrofolate reductase)
Sus scrofa (pig) : DHFR (dihydrofolate reductase)
Chlorocebus sabaeus (African green monkey) : DHFR (dihydrofolate reductase)
Heterocephalus glaber (naked mole-rat) : Dhfr (dihydrofolate reductase)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541829,274,170 - 29,283,028 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Dhfr
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 8768992
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.