Nuf2 (NUF2 component of NDC80 kinetochore complex) - Rat Genome Database

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Gene: Nuf2 (NUF2 component of NDC80 kinetochore complex) Chinchilla lanigera
Analyze
Symbol: Nuf2
Name: NUF2 component of NDC80 kinetochore complex
RGD ID: 8764915
Description: ENCODES a protein that exhibits microtubule binding (ortholog); INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); ASSOCIATED WITH breast cancer (ortholog); castration-resistant prostate carcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytosol (ortholog); kinetochore (ortholog); Ndc80 complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kinetochore protein Nuf2; NDC80 kinetochore complex component NUF2; NUF2, NDC80 kinetochore complex component
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546213,082,047 - 13,142,944 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546213,082,874 - 13,142,709 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nuf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546213,082,047 - 13,142,944 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546213,082,874 - 13,142,709 (-)NCBIChiLan1.0ChiLan1.0
NUF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381163,321,954 - 163,355,759 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1163,266,576 - 163,355,764 (+)EnsemblGRCh38hg38GRCh38
GRCh371163,291,744 - 163,325,549 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,558,347 - 161,592,177 (+)NCBINCBI36Build 36hg18NCBI36
Build 341160,023,382 - 160,057,205NCBI
Celera1136,396,004 - 136,429,820 (+)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1134,537,062 - 134,570,886 (+)NCBIHuRef
CHM1_11164,714,625 - 164,748,448 (+)NCBICHM1_1
T2T-CHM13v2.01162,666,885 - 162,701,025 (+)NCBIT2T-CHM13v2.0
Nuf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,325,503 - 169,359,033 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,325,503 - 169,359,033 (-)EnsemblGRCm39 Ensembl
GRCm381169,497,934 - 169,531,464 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,497,934 - 169,531,464 (-)EnsemblGRCm38mm10GRCm38
MGSCv371171,428,065 - 171,461,595 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361171,334,986 - 171,368,103 (-)NCBIMGSCv36mm8
Celera1171,916,559 - 171,956,575 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map176.84NCBI
Nuf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81384,226,448 - 84,290,957 (-)NCBIGRCr8
mRatBN7.21381,693,675 - 81,722,765 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1381,693,598 - 81,722,766 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1384,320,699 - 84,350,601 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01385,614,283 - 85,643,373 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01382,845,943 - 82,875,848 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01387,818,456 - 87,847,223 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1387,818,391 - 87,847,263 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01392,450,022 - 92,478,789 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41385,286,634 - 85,315,366 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11385,300,821 - 85,329,554 (-)NCBI
Celera1381,360,832 - 81,390,131 (-)NCBICelera
Cytogenetic Map13q24NCBI
NUF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2186,420,744 - 86,454,724 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1186,089,305 - 86,123,334 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01138,743,251 - 138,777,201 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11142,538,420 - 142,572,364 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1142,538,420 - 142,572,364 (+)Ensemblpanpan1.1panPan2
NUF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13819,574,122 - 19,599,821 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3819,574,125 - 19,599,064 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3819,631,382 - 19,659,692 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03819,658,875 - 19,687,209 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3819,658,875 - 19,687,186 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13819,627,147 - 19,652,037 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03819,985,502 - 20,013,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03820,277,530 - 20,302,431 (-)NCBIUU_Cfam_GSD_1.0
Nuf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344103,495,918 - 103,524,586 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648121,342,786 - 21,371,328 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648121,342,667 - 21,371,311 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl487,162,818 - 87,194,170 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1487,162,873 - 87,194,193 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2494,875,757 - 94,907,078 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12565,462,608 - 65,493,242 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2565,462,603 - 65,493,246 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605567,252,523 - 67,283,969 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nuf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248261,798,737 - 1,831,112 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248261,794,084 - 1,831,009 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000014278   ⟹   ENSCLAP00000014120
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495546213,082,047 - 13,142,944 (-)Ensembl
RefSeq Acc Id: XM_005398255   ⟹   XP_005398312
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546213,082,874 - 13,142,709 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521455   ⟹   XP_013376909
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546213,111,281 - 13,142,708 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013521456   ⟹   XP_013376910
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495546213,111,281 - 13,142,709 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005398312 (Get FASTA)   NCBI Sequence Viewer  
  XP_013376909 (Get FASTA)   NCBI Sequence Viewer  
  XP_013376910 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000014120
  ENSCLAP00000014120.1
RefSeq Acc Id: XP_005398312   ⟸   XM_005398255
- UniProtKB: A0A8C2VG13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376910   ⟸   XM_013521456
- UniProtKB: A0A8C2VG13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013376909   ⟸   XM_013521455
- UniProtKB: A0A8C2VG13 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000014120   ⟸   ENSCLAT00000014278

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009748 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014278 ENTREZGENE
  ENSCLAT00000014278.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.60 UniProtKB/TrEMBL
InterPro Kinetochore_Nuf2_N UniProtKB/TrEMBL
  Nuf2_N_sf UniProtKB/TrEMBL
NCBI Gene Nuf2 ENTREZGENE
PANTHER KINETOCHORE PROTEIN NUF2 UniProtKB/TrEMBL
  MEMBRALIN/KINETOCHORE PROTEIN NUF2 UniProtKB/TrEMBL
Pfam Nuf2 UniProtKB/TrEMBL
UniProt A0A8C2VG13 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Nuf2  NUF2 component of NDC80 kinetochore complex    NDC80 kinetochore complex component NUF2  Symbol and/or name change 5135510 APPROVED
2018-08-21 Nuf2  NDC80 kinetochore complex component NUF2    NUF2, NDC80 kinetochore complex component  Symbol and/or name change 5135510 APPROVED