Rpa3 (replication protein A3) - Rat Genome Database

Name: Rpa3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Rpa3 (replication protein A3) Chinchilla lanigera

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Symbol:

Rpa3

Name:

replication protein A3

RGD ID:

8760968

Description:

ENCODES a protein that exhibits damaged DNA binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN base-excision repair (ortholog); DNA repair (ortholog); DNA replication (ortholog); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; FOUND IN DNA replication factor A complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

replication protein A 14 kDa subunit; replication protein A3, 14kDa

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RPA3 (replication protein A3)	NCBI	Ortholog
Mus musculus (house mouse):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RPA3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RPA3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RPA3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RPA3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	14,723,751 - 14,727,290 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955432	14,723,933 - 14,727,356 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

base-excision repair (ISO)

DNA repair (ISO)

DNA replication (ISO)

double-strand break repair via homologous recombination (ISO)

mismatch repair (ISO)

nucleotide-excision repair (ISO)

regulation of cell population proliferation (ISO)

regulation of mitotic cell cycle (ISO)

Cellular Component

DNA replication factor A complex (ISO)

Molecular Function

damaged DNA binding (ISO)

protein binding (ISO)

single-stranded DNA binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mismatch repair pathway (ISO)

nucleotide excision repair pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Rpa3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	14,723,751 - 14,727,290 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955432	14,723,933 - 14,727,356 (-)	NCBI	ChiLan1.0	ChiLan1.0

RPA3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	7,636,518 - 7,718,607 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	7,636,518 - 7,718,607 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	7,676,149 - 7,758,238 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	7,643,100 - 7,724,763 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	7,449,816 - 7,531,478	NCBI
Celera	7	7,644,982 - 7,725,987 (-)	NCBI		Celera
Cytogenetic Map	7	p21.3	NCBI
HuRef	7	7,525,171 - 7,607,577 (-)	NCBI		HuRef
CHM1_1	7	7,676,293 - 7,757,838 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	7,754,317 - 7,837,139 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	7,723,782 - 7,804,410 (-)	NCBI

Rpa3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	8,255,936 - 8,259,141 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	8,255,936 - 8,259,173 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	8,255,936 - 8,259,141 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	8,255,936 - 8,259,173 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	8,205,936 - 8,209,141 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	8,205,937 - 8,209,113 (-)	NCBI		MGSCv36	mm8
Celera	6	8,397,638 - 8,400,833 (-)	NCBI		Celera
Cytogenetic Map	6	A1	NCBI
cM Map	6	3.53	NCBI

Rpa3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	37,270,966 - 37,273,997 (-)	NCBI		GRCr8
mRatBN7.2	4	36,304,649 - 36,307,755 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	36,304,651 - 36,307,709 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	41,272,230 - 41,275,262 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	37,198,431 - 37,201,463 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	35,609,727 - 35,612,758 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	34,279,320 - 34,282,351 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	34,279,320 - 34,282,351 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	34,139,498 - 34,142,529 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	33,304,334 - 33,307,365 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	33,422,871 - 33,425,905 (-)	NCBI
Celera	4	31,808,230 - 31,811,261 (-)	NCBI		Celera
Cytogenetic Map	4	q21	NCBI

RPA3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	12,536,575 - 12,540,340 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	60,861,290 - 60,864,770 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	8,361,623 - 8,365,098 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	7,713,632 - 7,794,199 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	7,713,629 - 7,717,169 (-)	Ensembl	panpan1.1		panPan2

RPA3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	23,230,447 - 23,234,554 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	2,893,352 - 2,893,717 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	22,805,480 - 22,809,588 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	23,045,005 - 23,049,117 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	14	23,197,309 - 23,201,240 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	22,930,101 - 22,934,209 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	23,187,728 - 23,191,835 (-)	NCBI		UU_Cfam_GSD_1.0

Rpa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	36,592,667 - 36,596,130 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936585	2,266,706 - 2,272,259 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936585	2,267,113 - 2,270,635 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPA3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	77,910,881 - 77,937,060 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	77,910,876 - 77,914,872 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RPA3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	50,570,027 - 50,574,270 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	50,570,751 - 50,574,216 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	53,812,402 - 53,816,643 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rpa3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	5,247,033 - 5,253,413 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624813	5,248,794 - 5,252,264 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005388093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01031047	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01168506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000005021 ⟹ ENSCLAP00000004929

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955432	14,723,751 - 14,727,290 (-)	Ensembl

RefSeq Acc Id:

XM_005388093 ⟹ XP_005388150

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955432	14,723,933 - 14,727,356 (-)	NCBI

Sequence:

show sequence

ATAGGCGCTAGCGGGGTTCTTTTTCCGTCGTCCGCGCCCTGTTTCCCGCCAGGCGGAGGCTTCA
TCATGGTGGACGTGGTGGAGTTGCCCAAGTCGCGCATCAACGCCAGCATGCTCTCTCAGTTCAT
TGACCGGCCGGTCTGCTTCGTAGGGAGGCTGGAAAAGATTCATCCCACTGGAAAAATGTTTATC
CTTTCGGATGGAGAAGGAAAAAATGGAACCGTTGAATTAATGGAGCCACTTGATGAAGAACTAT
CTGGAATCGTGGAAGTAGTTGGAAGAGTAACAGCTAAGGCAACCATCATGTGTGCCTCTTACAT
CCAGTTCAGAGAAGATAGCAGTCCTTTCGATCTGGGACTTTACAATGAAGCAGTGAAAATTATC
CATGAATTCCCTCAGTTTTTTCCTTTTGGAGTGCAACATGAATCTTGATGGATTTTTTTTATGA
TTTCAAGAAGCTACATCGATGGATATTAAAGGAATCCCCTCATATTTGAGGGAGAGAACTCTTT
GATTTCTAATATTTAATTTGTTGTTTTTAAAATTCCACTTATCAAATGTTAGCTCTTTCAATCT
GCATTTTTTGATGGAAGTGGTGTATTATTGGCAGTTATAAAAAAAATTGCTACTACATTGTATG
GTCAGATAAGATGCAATAACAAAGCATCTTGTGTTTGTGTTTCTATTTTATTCATGAACTTTGG
TATATACTATTGATTACTTGATCTTTATTTTTGTAAGCATGTATTCAGACACAAACTTGGAATT
TCATAACGGTAAGGTCATGTCTTAGGCCTAGCAAATGAAACTCTAGGTCAACTCTGTTAAGGAC
TTACTAGCTCATAAATTCTACCATGTTAATTATTCTTCAATAAAAGTGATTTTTTTTGTTGGTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005388150	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000004929
	ENSCLAP00000004929.1

RefSeq Acc Id:	XP_005388150 ⟸ XM_005388093
- UniProtKB:	A0A8C2UT70 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVDVVELPKSRINASMLSQFIDRPVCFVGRLEKIHPTGKMFILSDGEGKNGTVELMEPLDEELS GIVEVVGRVTAKATIMCASYIQFREDSSPFDLGLYNEAVKIIHEFPQFFPFGVQHES hide sequence

Ensembl Acc Id:

ENSCLAP00000004929 ⟸ ENSCLAT00000005021

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000003500	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000005021	ENTREZGENE
	ENSCLAT00000005021.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.140	UniProtKB/TrEMBL
InterPro	NA-bd_OB-fold	UniProtKB/TrEMBL
	Rfa2	UniProtKB/TrEMBL
NCBI Gene	Rpa3	ENTREZGENE
PANTHER	REPLICATION PROTEIN A 14 KDA SUBUNIT	UniProtKB/TrEMBL
	REPLICATION PROTEIN A3	UniProtKB/TrEMBL
Pfam	Rep_fac-A_3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50249	UniProtKB/TrEMBL
UniProt	A0A8C2UT70	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Rpa3	replication protein A3		replication protein A3, 14kDa	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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