Arrb1 (arrestin beta 1) - Rat Genome Database

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Gene: Arrb1 (arrestin beta 1) Chinchilla lanigera
Analyze
Symbol: Arrb1
Name: arrestin beta 1
RGD ID: 8759443
Description: ENCODES a protein that exhibits alpha-1A adrenergic receptor binding (ortholog); alpha-1B adrenergic receptor binding (ortholog); angiotensin receptor binding (ortholog); INVOLVED IN endocytosis (ortholog); follicle-stimulating hormone signaling pathway (ortholog); G protein-coupled receptor internalization (ortholog); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; corticotropin-releasing hormone signaling pathway; ASSOCIATED WITH Arteriovenous Fistula (ortholog); colitis (ortholog); congestive heart failure (ortholog); FOUND IN basolateral plasma membrane (ortholog); chromatin (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: arrestin, beta 1; beta-arrestin-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541416,478,843 - 16,562,135 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541416,478,843 - 16,568,050 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
endocytosis  (ISO)
follicle-stimulating hormone signaling pathway  (ISO)
G protein-coupled receptor internalization  (ISO)
G protein-coupled receptor signaling pathway  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of GTPase activity  (ISO)
negative regulation of interleukin-6 production  (ISO)
negative regulation of interleukin-8 production  (ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of Notch signaling pathway  (ISO)
negative regulation of protein phosphorylation  (ISO)
negative regulation of protein ubiquitination  (ISO)
phototransduction  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of histone acetylation  (ISO)
positive regulation of histone H4 acetylation  (ISO)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of protein binding  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein ubiquitination  (ISO)
positive regulation of receptor internalization  (ISO)
positive regulation of Rho protein signal transduction  (ISO)
positive regulation of smooth muscle cell apoptotic process  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
proteasome-mediated ubiquitin-dependent protein catabolic process  (ISO)
protein ubiquitination  (ISO)
regulation of apoptotic process  (ISO)
regulation of G protein-coupled receptor signaling pathway  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
regulation of transcription, DNA-templated  (ISO)
response to xenobiotic stimulus  (ISO)
stress fiber assembly  (ISO)
ubiquitin-dependent protein catabolic process  (ISO)

Cellular Component

References


Genomics

Comparative Map Data
Arrb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541416,478,843 - 16,562,135 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541416,478,843 - 16,568,050 (+)NCBIChiLan1.0ChiLan1.0
ARRB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1175,260,122 - 75,351,705 (-)EnsemblGRCh38hg38GRCh38
GRCh381175,260,122 - 75,351,662 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371174,971,166 - 75,062,705 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,654,130 - 74,740,521 (-)NCBINCBI36hg18NCBI36
Build 341174,654,129 - 74,740,521NCBI
Celera1172,283,036 - 72,369,427 (-)NCBI
Cytogenetic Map11q13.4NCBI
HuRef1171,268,798 - 71,360,118 (-)NCBIHuRef
CHM1_11174,854,770 - 74,946,464 (-)NCBICHM1_1
Arrb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,184,356 - 99,255,979 (+)NCBIGRCm39mm39
GRCm39 Ensembl799,184,673 - 99,255,978 (+)Ensembl
GRCm38799,535,147 - 99,606,772 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl799,535,466 - 99,606,771 (+)EnsemblGRCm38mm10GRCm38
MGSCv377106,683,996 - 106,755,281 (+)NCBIGRCm37mm9NCBIm37
MGSCv36799,409,569 - 99,480,854 (+)NCBImm8
Celera799,859,615 - 99,932,041 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map754.09NCBI
Arrb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21153,837,964 - 153,912,111 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1164,502,389 - 164,593,139 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01164,502,099 - 164,573,947 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01170,705,795 - 170,777,617 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41156,871,564 - 156,937,540 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11156,949,969 - 157,015,946 (+)NCBI
Celera1151,924,752 - 151,989,492 (+)NCBICelera
Cytogenetic Map1q32NCBI
ARRB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11173,624,254 - 73,670,495 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1173,630,276 - 73,654,155 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01170,319,935 - 70,411,276 (-)NCBIMhudiblu_PPA_v0panPan3
ARRB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12123,261,020 - 23,304,448 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2123,235,711 - 23,297,786 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2122,990,721 - 23,068,006 (+)NCBI
ROS_Cfam_1.02123,428,040 - 23,505,333 (+)NCBI
UMICH_Zoey_3.12123,226,359 - 23,303,832 (+)NCBI
UNSW_CanFamBas_1.02123,422,622 - 23,499,929 (+)NCBI
UU_Cfam_GSD_1.02123,340,581 - 23,417,904 (+)NCBI
Arrb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494762,490,018 - 62,573,146 (-)NCBI
SpeTri2.0NW_0049364984,089,621 - 4,172,749 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARRB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl99,513,856 - 9,597,959 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.199,516,944 - 9,597,446 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2910,659,892 - 10,767,092 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARRB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,489,358 - 66,580,167 (-)NCBI
ChlSab1.1 Ensembl166,490,102 - 66,580,154 (-)Ensembl
Vero_WHO_p1.0NW_02366604359,230,347 - 59,326,828 (+)NCBI
Arrb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248171,750,448 - 1,828,399 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000021352   ⟹   ENSCLAP00000021151
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541416,478,843 - 16,562,135 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000021353   ⟹   ENSCLAP00000021152
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541416,478,972 - 16,562,135 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000021354   ⟹   ENSCLAP00000021153
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541416,544,705 - 16,562,135 (+)Ensembl
RefSeq Acc Id: XM_005379893   ⟹   XP_005379950
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541416,478,843 - 16,568,050 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005379950 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005379950   ⟸   XM_005379893
- Sequence:
RefSeq Acc Id: ENSCLAP00000021151   ⟸   ENSCLAT00000021352
RefSeq Acc Id: ENSCLAP00000021153   ⟸   ENSCLAT00000021354
RefSeq Acc Id: ENSCLAP00000021152   ⟸   ENSCLAT00000021353


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014486 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000021151 ENTREZGENE
Ensembl Transcript ENSCLAT00000021352 ENTREZGENE
NCBI Gene Arrb1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Arrb1  arrestin beta 1    arrestin, beta 1  Symbol and/or name change 5135510 APPROVED