Rapgef4 (Rap guanine nucleotide exchange factor 4) - Rat Genome Database

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Gene: Rapgef4 (Rap guanine nucleotide exchange factor 4) Chinchilla lanigera
Analyze
Symbol: Rapgef4
Name: Rap guanine nucleotide exchange factor 4
RGD ID: 8758984
Description: ENCODES a protein that exhibits cAMP binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); brain development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Burns (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: Rap guanine nucleotide exchange factor (GEF) 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554492,171,924 - 2,462,451 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554492,172,354 - 2,453,367 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
autistic disorder  (ISO)
Burns  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References


Genomics

Comparative Map Data
Rapgef4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554492,171,924 - 2,462,451 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554492,172,354 - 2,453,367 (-)NCBIChiLan1.0ChiLan1.0
RAPGEF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2172,735,274 - 173,052,893 (+)EnsemblGRCh38hg38GRCh38
GRCh382172,735,282 - 173,052,893 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372173,600,573 - 173,917,621 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362173,308,771 - 173,625,867 (+)NCBINCBI36hg18NCBI36
Build 342173,426,113 - 173,743,122NCBI
Celera2167,213,920 - 167,531,026 (+)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2165,478,909 - 165,797,009 (+)NCBIHuRef
CHM1_12173,607,657 - 173,924,727 (+)NCBICHM1_1
Rapgef4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39271,811,559 - 72,087,818 (+)NCBIGRCm39mm39
GRCm39 Ensembl271,811,584 - 72,087,818 (+)Ensembl
GRCm38271,981,215 - 72,257,474 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl271,981,240 - 72,257,474 (+)EnsemblGRCm38mm10GRCm38
MGSCv37271,819,344 - 72,094,433 (+)NCBIGRCm37mm9NCBIm37
MGSCv36271,782,126 - 72,057,215 (+)NCBImm8
Celera273,684,323 - 73,945,757 (+)NCBICelera
Cytogenetic Map2C3NCBI
Rapgef4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2356,809,388 - 57,101,332 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl356,809,270 - 57,102,316 (+)Ensembl
Rnor_6.0358,632,338 - 58,925,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl358,632,476 - 58,924,038 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0365,122,705 - 65,409,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4354,396,312 - 54,717,148 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1354,578,917 - 54,613,517 (+)NCBI
Celera356,352,070 - 56,643,335 (+)NCBICelera
Cytogenetic Map3q23NCBI
RAPGEF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B177,485,404 - 177,794,769 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B177,655,733 - 177,793,644 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B60,022,738 - 60,339,981 (+)NCBIMhudiblu_PPA_v0panPan3
RAPGEF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13617,087,488 - 17,323,504 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3617,087,488 - 17,323,220 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3617,044,798 - 17,327,450 (+)NCBI
ROS_Cfam_1.03617,166,818 - 17,450,241 (+)NCBI
UMICH_Zoey_3.13617,247,410 - 17,530,838 (+)NCBI
UNSW_CanFamBas_1.03617,246,048 - 17,529,604 (+)NCBI
UU_Cfam_GSD_1.03617,349,948 - 17,632,781 (+)NCBI
Rapgef4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303134,168,378 - 134,452,112 (+)NCBI
SpeTri2.0NW_0049365092,722,279 - 3,006,436 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAPGEF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1578,773,285 - 79,095,041 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11578,773,270 - 79,094,490 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21588,093,533 - 88,416,683 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAPGEF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11058,233,503 - 58,549,337 (+)NCBI
ChlSab1.1 Ensembl1058,233,654 - 58,549,331 (+)Ensembl
Vero_WHO_p1.0NW_023666040141,024,710 - 141,334,996 (-)NCBI
Rapgef4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478710,062,677 - 10,369,132 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000005522   ⟹   ENSCLAP00000005425
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554492,171,924 - 2,462,451 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000005523   ⟹   ENSCLAP00000005426
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554492,171,924 - 2,453,382 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000005524   ⟹   ENSCLAP00000005427
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554492,171,924 - 2,453,382 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000005525   ⟹   ENSCLAP00000005428
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554492,171,924 - 2,386,747 (-)Ensembl
RefSeq Acc Id: XM_005393202   ⟹   XP_005393259
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,453,367 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005393203   ⟹   XP_005393260
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,453,367 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005393204   ⟹   XP_005393261
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,358,274 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005393205   ⟹   XP_005393262
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,386,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005393208   ⟹   XP_005393265
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,287,262 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518783   ⟹   XP_013374237
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,283,948 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518784   ⟹   XP_013374238
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,386,636 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013518785   ⟹   XP_013374239
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554492,172,354 - 2,287,152 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_005393260   ⟸   XM_005393203
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005393259   ⟸   XM_005393202
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005393262   ⟸   XM_005393205
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005393261   ⟸   XM_005393204
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005393265   ⟸   XM_005393208
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_013374238   ⟸   XM_013518784
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_013374239   ⟸   XM_013518785
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_013374237   ⟸   XM_013518783
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCLAP00000005428   ⟸   ENSCLAT00000005525
RefSeq Acc Id: ENSCLAP00000005427   ⟸   ENSCLAT00000005524
RefSeq Acc Id: ENSCLAP00000005426   ⟸   ENSCLAT00000005523
RefSeq Acc Id: ENSCLAP00000005425   ⟸   ENSCLAT00000005522


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003849 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000005426 ENTREZGENE
  ENSCLAP00000005427 ENTREZGENE
  ENSCLAP00000005428 ENTREZGENE
Ensembl Transcript ENSCLAT00000005523 ENTREZGENE
  ENSCLAT00000005524 ENTREZGENE
  ENSCLAT00000005525 ENTREZGENE
NCBI Gene Rapgef4 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Rapgef4  Rap guanine nucleotide exchange factor 4    Rap guanine nucleotide exchange factor (GEF) 4  Symbol and/or name change 5135510 APPROVED