Hmgcr (3-hydroxy-3-methylglutaryl-CoA reductase) - Rat Genome Database

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Gene: Hmgcr (3-hydroxy-3-methylglutaryl-CoA reductase) Chinchilla lanigera
Analyze
Symbol: Hmgcr
Name: 3-hydroxy-3-methylglutaryl-CoA reductase
RGD ID: 8758614
Description: ENCODES a protein that exhibits coenzyme A binding (ortholog); hydroxymethylglutaryl-CoA reductase (NADPH) activity (ortholog); identical protein binding (ortholog); INVOLVED IN aging (ortholog); bile acid signaling pathway (ortholog); cholesterol biosynthetic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; bile acid signaling pathway; cholesterol biosynthetic pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); Alzheimer's disease (ortholog); FOUND IN endoplasmic reticulum (ortholog); intracellular membrane-bounded organelle (ortholog); peroxisomal membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,359,884 - 25,380,745 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,362,165 - 25,380,611 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References


Genomics

Comparative Map Data
Hmgcr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,359,884 - 25,380,745 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,362,165 - 25,380,611 (-)NCBIChiLan1.0ChiLan1.0
HMGCR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl575,336,329 - 75,364,001 (+)EnsemblGRCh38hg38GRCh38
GRCh38575,336,334 - 75,362,116 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37574,632,993 - 74,657,941 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,668,855 - 74,693,681 (+)NCBINCBI36hg18NCBI36
Build 34574,668,854 - 74,693,681NCBI
Celera570,526,169 - 70,551,102 (+)NCBI
Cytogenetic Map5q13.3NCBI
HuRef569,838,165 - 69,863,098 (+)NCBIHuRef
CHM1_1574,065,715 - 74,090,648 (+)NCBICHM1_1
Hmgcr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391396,785,470 - 96,807,444 (-)NCBIGRCm39mm39
GRCm39 Ensembl1396,785,475 - 96,807,444 (-)Ensembl
GRCm381396,648,962 - 96,670,936 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1396,648,967 - 96,670,936 (-)EnsemblGRCm38mm10GRCm38
MGSCv371397,418,917 - 97,440,891 (-)NCBIGRCm37mm9NCBIm37
MGSCv361397,750,033 - 97,771,547 (-)NCBImm8
Celera13100,288,206 - 100,310,264 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.65NCBI
Hmgcr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2227,997,523 - 28,018,983 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl227,997,525 - 28,019,703 (-)Ensembl
Rnor_6.0227,480,224 - 27,500,654 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,480,226 - 27,500,654 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0246,592,881 - 46,614,276 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,127,504 - 27,149,580 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1227,047,872 - 27,069,949 (-)NCBI
Celera224,043,814 - 24,065,183 (-)NCBICelera
RH 3.4 Map213.3RGD
Cytogenetic Map2q12NCBI
HMGCR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1540,548,919 - 40,573,785 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl540,548,919 - 40,573,785 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0539,936,630 - 39,961,519 (-)NCBIMhudiblu_PPA_v0panPan3
HMGCR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1330,970,037 - 30,988,987 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl330,970,037 - 30,990,294 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha332,211,759 - 32,233,728 (-)NCBI
ROS_Cfam_1.0330,898,455 - 30,920,631 (-)NCBI
UMICH_Zoey_3.1330,828,548 - 30,850,686 (-)NCBI
UNSW_CanFamBas_1.0330,798,860 - 30,820,987 (-)NCBI
UU_Cfam_GSD_1.0331,177,224 - 31,199,407 (-)NCBI
Hmgcr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213189,458,452 - 189,480,240 (+)NCBI
SpeTri2.0NW_0049365491,378,536 - 1,400,501 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMGCR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl284,380,225 - 84,402,956 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1284,380,245 - 84,401,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,967,367 - 85,988,242 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap2q22NCBI
HMGCR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,664,784 - 69,690,343 (+)NCBI
ChlSab1.1 Ensembl469,665,417 - 69,688,686 (+)Ensembl
Vero_WHO_p1.0NW_02366604918,450,156 - 18,475,169 (+)NCBI
Hmgcr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624951681,559 - 711,476 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014834   ⟹   ENSCLAP00000014675
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495542525,359,884 - 25,380,745 (-)Ensembl
RefSeq Acc Id: XM_005386052   ⟹   XP_005386109
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542525,362,165 - 25,380,611 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386109 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005386109   ⟸   XM_005386052
- Sequence:
RefSeq Acc Id: ENSCLAP00000014675   ⟸   ENSCLAT00000014834


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000010132 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000014675 ENTREZGENE
Ensembl Transcript ENSCLAT00000014834 ENTREZGENE
NCBI Gene Hmgcr ENTREZGENE