Dsc1 (desmocollin 1) - Rat Genome Database

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Gene: Dsc1 (desmocollin 1) Chinchilla lanigera
Analyze
Symbol: Dsc1
Name: desmocollin 1
RGD ID: 8758345
Description: ASSOCIATED WITH Chronic Periodontitis (ortholog); Familial Amyloid Polyneuropathies (ortholog); genetic disease (ortholog); FOUND IN desmosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: desmocollin-1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540218,513,817 - 18,543,720 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540218,514,657 - 18,543,449 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
desmosome  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dsc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540218,513,817 - 18,543,720 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540218,514,657 - 18,543,449 (-)NCBIChiLan1.0ChiLan1.0
DSC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381831,129,236 - 31,162,856 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1831,129,236 - 31,162,856 (-)EnsemblGRCh38hg38GRCh38
GRCh371828,709,199 - 28,742,819 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361826,963,197 - 26,996,817 (-)NCBINCBI36Build 36hg18NCBI36
Build 341826,963,213 - 26,996,817NCBI
Celera1825,517,395 - 25,550,695 (-)NCBICelera
Cytogenetic Map18q12.1ENTREZGENE
HuRef1825,564,926 - 25,598,451 (-)NCBIHuRef
CHM1_11828,636,224 - 28,670,180 (-)NCBICHM1_1
T2T-CHM13v2.01831,319,561 - 31,418,220 (-)NCBIT2T-CHM13v2.0
Dsc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391820,216,528 - 20,247,830 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1820,217,241 - 20,247,928 (-)EnsemblGRCm39 Ensembl
GRCm381820,083,471 - 20,114,773 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1820,084,184 - 20,114,871 (-)EnsemblGRCm38mm10GRCm38
MGSCv371820,243,204 - 20,273,274 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361820,228,175 - 20,257,690 (-)NCBIMGSCv36mm8
Celera1820,586,914 - 20,616,991 (-)NCBICelera
Cytogenetic Map18A2NCBI
cM Map1811.17NCBI
Dsc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81811,774,711 - 11,831,868 (-)NCBIGRCr8
mRatBN7.21811,499,936 - 11,556,801 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1811,502,003 - 11,528,494 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01811,877,918 - 11,906,828 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1811,877,561 - 11,906,827 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01811,677,463 - 11,706,220 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41811,953,172 - 11,979,048 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11811,980,205 - 12,050,014 (-)NCBI
Celera1811,519,677 - 11,545,279 (-)NCBICelera
Cytogenetic Map18p12NCBI
DSC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21748,532,785 - 48,568,696 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11834,225,380 - 34,261,291 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01824,358,116 - 24,393,604 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11827,957,559 - 27,990,818 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1827,955,717 - 27,990,818 (-)Ensemblpanpan1.1panPan2
DSC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1758,322,959 - 58,350,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl758,322,959 - 58,457,978 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha757,760,078 - 57,787,216 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0758,308,188 - 58,335,350 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl758,308,188 - 58,387,461 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1757,984,457 - 58,011,580 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0758,009,130 - 58,036,271 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0758,299,991 - 58,327,147 (+)NCBIUU_Cfam_GSD_1.0
Dsc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494454,011,718 - 54,039,448 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366822,013,414 - 2,040,148 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366822,013,414 - 2,040,148 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DSC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6115,039,722 - 115,076,097 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16115,042,225 - 115,076,097 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26107,662,809 - 107,696,605 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DSC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11849,547,141 - 49,578,226 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1849,549,287 - 49,576,545 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605024,194,322 - 24,223,576 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dsc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247701,710,170 - 1,740,454 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247701,709,920 - 1,743,005 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000019065   ⟹   ENSCLAP00000018880
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540218,513,817 - 18,543,720 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000019066   ⟹   ENSCLAP00000018881
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540218,513,817 - 18,543,720 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000019067   ⟹   ENSCLAP00000018882
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540218,517,170 - 18,543,139 (-)Ensembl
RefSeq Acc Id: XM_005372738   ⟹   XP_005372795
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540218,514,657 - 18,543,449 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005372739   ⟹   XP_005372796
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540218,516,984 - 18,543,449 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005372795 (Get FASTA)   NCBI Sequence Viewer  
  XP_005372796 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018880
  ENSCLAP00000018880.1
  ENSCLAP00000018881
  ENSCLAP00000018881.1
  ENSCLAP00000018882.1
Reference Protein Sequences
RefSeq Acc Id: XP_005372795   ⟸   XM_005372738
- Peptide Label: isoform X1
- UniProtKB: A0A8C2YRY4 (UniProtKB/TrEMBL),   A0A8C2YRY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005372796   ⟸   XM_005372739
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VQ35 (UniProtKB/TrEMBL),   A0A8C2YRY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000018881   ⟸   ENSCLAT00000019066
RefSeq Acc Id: ENSCLAP00000018882   ⟸   ENSCLAT00000019067
RefSeq Acc Id: ENSCLAP00000018880   ⟸   ENSCLAT00000019065
Protein Domains
Cadherin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012931 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019065 ENTREZGENE
  ENSCLAT00000019065.1 UniProtKB/TrEMBL
  ENSCLAT00000019066 ENTREZGENE
  ENSCLAT00000019066.1 UniProtKB/TrEMBL
  ENSCLAT00000019067.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.900.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_cytoplasmic-dom UniProtKB/TrEMBL
  Cadherin_pro_dom UniProtKB/TrEMBL
  Catenin-bd_sf UniProtKB/TrEMBL
  Desmosomal_cadherin UniProtKB/TrEMBL
NCBI Gene Dsc1 ENTREZGENE
PANTHER CADHERIN-13 UniProtKB/TrEMBL
  CADHERIN-23 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_C UniProtKB/TrEMBL
  Cadherin_pro UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
  DESMOCADHERN UniProtKB/TrEMBL
  DESMOCOLLIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
SMART Cadherin_pro UniProtKB/TrEMBL
  SM00112 UniProtKB/TrEMBL
Superfamily-SCOP SSF49313 UniProtKB/TrEMBL
UniProt A0A8C2VQ35 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YRY1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YRY4 ENTREZGENE, UniProtKB/TrEMBL