Rusc1 (RUN and SH3 domain containing 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rusc1 (RUN and SH3 domain containing 1) Chinchilla lanigera
Analyze
Symbol: Rusc1
Name: RUN and SH3 domain containing 1
RGD ID: 8754799
Description: ENCODES a protein that exhibits actin binding (ortholog); INVOLVED IN protein polyubiquitination (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN cytoplasmic vesicle (ortholog); cytosol (ortholog); early endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: RUN and SH3 domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,765,800 - 1,773,889 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,765,364 - 1,773,889 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rusc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,765,800 - 1,773,889 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,765,364 - 1,773,889 (+)NCBIChiLan1.0ChiLan1.0
RUSC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381155,320,894 - 155,331,118 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1155,320,894 - 155,331,114 (+)EnsemblGRCh38hg38GRCh38
GRCh371155,290,685 - 155,300,909 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361153,557,264 - 153,567,533 (+)NCBINCBI36Build 36hg18NCBI36
Build 341152,107,440 - 152,113,976NCBI
Celera1128,363,782 - 128,374,051 (+)NCBICelera
Cytogenetic Map1q22NCBI
HuRef1126,652,942 - 126,663,296 (+)NCBIHuRef
CHM1_11156,686,081 - 156,696,350 (+)NCBICHM1_1
T2T-CHM13v2.01154,459,434 - 154,469,658 (+)NCBIT2T-CHM13v2.0
Rusc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39388,991,282 - 89,000,670 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl388,991,288 - 89,000,618 (-)EnsemblGRCm39 Ensembl
GRCm38389,083,975 - 89,093,363 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,083,981 - 89,093,311 (-)EnsemblGRCm38mm10GRCm38
MGSCv37388,887,899 - 88,897,285 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,169,908 - 89,179,217 (-)NCBIMGSCv36mm8
Celera389,122,668 - 89,132,054 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.01NCBI
Rusc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82176,785,711 - 176,794,981 (-)NCBIGRCr8
mRatBN7.22174,487,921 - 174,497,266 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2174,486,665 - 174,507,776 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02188,394,114 - 188,403,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02207,806,473 - 207,815,974 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,157,849 - 181,167,536 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2168,432,165 - 168,441,279 (-)NCBICelera
Cytogenetic Map2q34NCBI
RUSC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2194,513,392 - 94,523,637 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,244,718 - 94,254,964 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01130,665,390 - 130,675,635 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11134,270,420 - 134,280,592 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1134,270,420 - 134,280,592 (+)Ensemblpanpan1.1panPan2
RUSC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,232,791 - 42,240,862 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,233,156 - 42,241,345 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,723,723 - 41,731,683 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,101,999 - 42,109,959 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,102,000 - 42,109,075 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1741,881,877 - 41,889,835 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0741,935,655 - 41,943,611 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,219,647 - 42,227,604 (-)NCBIUU_Cfam_GSD_1.0
Rusc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,778,226 - 25,787,715 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,808,546 - 4,818,221 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,808,620 - 4,818,097 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUSC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,489,207 - 94,499,256 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,489,202 - 94,499,993 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,280,858 - 103,291,688 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RUSC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1208,504,123 - 8,514,113 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl208,503,727 - 8,513,519 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660387,841,479 - 7,851,435 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rusc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624885949,542 - 957,142 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000008072   ⟹   ENSCLAP00000007952
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555451,765,800 - 1,773,889 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000008073   ⟹   ENSCLAP00000007953
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555451,765,800 - 1,773,889 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000008074   ⟹   ENSCLAP00000007954
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555451,765,800 - 1,773,889 (+)Ensembl
RefSeq Acc Id: XM_013508229   ⟹   XP_013363683
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555451,765,800 - 1,773,889 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013508230   ⟹   XP_013363684
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555451,765,364 - 1,773,889 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013508231   ⟹   XP_013363685
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555451,765,800 - 1,773,889 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013508232   ⟹   XP_013363686
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555451,765,800 - 1,773,889 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013508233   ⟹   XP_013363687
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555451,768,114 - 1,773,889 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013363684   ⟸   XM_013508230
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UZ89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363683   ⟸   XM_013508229
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UZ89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363685   ⟸   XM_013508231
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UZ89 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363686   ⟸   XM_013508232
- Peptide Label: isoform X4
- UniProtKB: A0A8C2UZ94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013363687   ⟸   XM_013508233
- Peptide Label: isoform X5
- UniProtKB: A0A8C2UZT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007952   ⟸   ENSCLAT00000008072
RefSeq Acc Id: ENSCLAP00000007953   ⟸   ENSCLAT00000008073
RefSeq Acc Id: ENSCLAP00000007954   ⟸   ENSCLAT00000008074
Protein Domains
RUN   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005579 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000008072 ENTREZGENE
  ENSCLAT00000008072.1 UniProtKB/TrEMBL
  ENSCLAT00000008073 ENTREZGENE
  ENSCLAT00000008073.1 UniProtKB/TrEMBL
  ENSCLAT00000008074 ENTREZGENE
  ENSCLAT00000008074.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.900 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro Run_dom UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/TrEMBL
  RUN_RUSC1 UniProtKB/TrEMBL
  RUSC1_2 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Rusc1 ENTREZGENE
PANTHER RUN AND SH3 DOMAIN CONTAINING UniProtKB/TrEMBL
  RUN AND SH3 DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam RUN UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PROSITE RUN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART RUN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A8C2UZ89 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UZ94 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UZT7 ENTREZGENE, UniProtKB/TrEMBL