Dld (dihydrolipoamide dehydrogenase) - Rat Genome Database

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Gene: Dld (dihydrolipoamide dehydrogenase) Chinchilla lanigera
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Symbol: Dld
Name: dihydrolipoamide dehydrogenase
RGD ID: 8753974
Description: ENCODES a protein that exhibits dihydrolipoyl dehydrogenase activity (ortholog); flavin adenine dinucleotide binding (ortholog); lipoamide binding (ortholog); INVOLVED IN 2-oxoglutarate metabolic process (ortholog); acetyl-CoA biosynthetic process from pyruvate (ortholog); aging (ortholog); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; ASSOCIATED WITH Congenital Infantile Lactic Acidosis due to LAD Deficiency (ortholog); genetic disease (ortholog); Leigh disease (ortholog); FOUND IN acrosomal matrix (ortholog); cilium (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: dihydrolipoyl dehydrogenase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541012,212,963 - 12,238,561 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541012,212,981 - 12,238,561 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
2-aminoadipic 2-oxoadipic aciduria pathway  (ISO)
3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway  (ISO)
3-hydroxyisobutyric aciduria pathway  (ISO)
3-methylcrotonyl CoA carboxylase 1 deficiency pathway  (ISO)
3-methylglutaconic aciduria type 1 pathway  (ISO)
3-methylglutaconic aciduria type 3 pathway  (ISO)
citric acid cycle pathway  (ISO)
dihydropyrimidine dehydrogenase deficiency pathway  (ISO)
dimethylglycine dehydrogenase deficiency pathway  (ISO)
folate cycle metabolic pathway  (ISO)
fumaric aciduria pathway  (ISO)
glutaric aciduria type I pathway  (ISO)
hyperlysinemia pathway  (ISO)
isobutyryl-CoA dehydrogenase deficiency pathway  (ISO)
isovaleric acidemia pathway  (ISO)
Leigh disease pathway  (ISO)
lysine degradation pathway  (ISO)
malonic aciduria pathway  (ISO)
maple syrup urine disease pathway  (ISO)
methylmalonate semialdehyde dehydrogenase deficiency pathway  (ISO)
methylmalonic acidemia pathway  (ISO)
methylmalonic aciduria, cobalamin-related pathway  (ISO)
mitochondrial complex II deficiency pathway  (ISO)
nonketotic hyperglycinemia pathway  (ISO)
primary hyperoxaluria type 2 pathway  (ISO)
propanoate metabolic pathway  (ISO)
propionic acidemia pathway  (ISO)
pyruvate decarboxylase deficiency pathway  (ISO)
pyruvate dehydrogenase E1 deficiency pathway  (ISO)
pyruvate dehydrogenase E2 deficiency pathway  (ISO)
pyruvate dehydrogenase E3 deficiency pathway  (ISO)
pyruvate kinase deficiency of red cells pathway  (ISO)
pyruvate metabolic pathway  (ISO)
saccharopinuria pathway  (ISO)
sarcosinemia pathway  (ISO)
valine, leucine and isoleucine degradation pathway  (ISO)

References


Genomics

Comparative Map Data
Dld
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541012,212,963 - 12,238,561 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541012,212,981 - 12,238,561 (+)NCBIChiLan1.0ChiLan1.0
DLD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7107,891,162 - 107,931,730 (+)EnsemblGRCh38hg38GRCh38
GRCh387107,891,107 - 107,921,198 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377107,531,552 - 107,561,643 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367107,318,822 - 107,348,879 (+)NCBINCBI36hg18NCBI36
Build 347107,125,561 - 107,154,360NCBI
Celera7102,338,571 - 102,368,626 (+)NCBI
Cytogenetic Map7q31.1NCBI
HuRef7101,894,030 - 101,924,084 (+)NCBIHuRef
CHM1_17107,465,307 - 107,495,360 (+)NCBICHM1_1
CRA_TCAGchr7v27106,892,712 - 106,922,768 (+)NCBI
Dld
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391231,381,561 - 31,401,470 (-)NCBIGRCm39mm39
GRCm39 Ensembl1231,381,276 - 31,401,452 (-)Ensembl
GRCm381231,331,562 - 31,351,471 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1231,331,277 - 31,351,453 (-)EnsemblGRCm38mm10GRCm38
MGSCv371232,016,427 - 32,036,302 (-)NCBIGRCm37mm9NCBIm37
MGSCv361231,917,620 - 31,937,454 (-)NCBImm8
Celera1232,779,653 - 32,799,528 (-)NCBICelera
Cytogenetic Map12A2NCBI
cM Map1213.43NCBI
Dld
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2647,904,153 - 47,924,814 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl647,903,914 - 47,924,795 (-)Ensembl
Rnor_6.0650,597,677 - 50,618,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl650,597,677 - 50,618,694 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0659,273,427 - 59,293,925 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4649,185,188 - 49,205,894 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1649,188,314 - 49,209,020 (-)NCBI
Celera647,106,161 - 47,126,575 (-)NCBICelera
Cytogenetic Map6q16NCBI
DLD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17112,593,934 - 112,623,629 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7112,593,934 - 112,623,629 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0799,872,020 - 99,901,884 (+)NCBIMhudiblu_PPA_v0panPan3
DLD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11812,703,340 - 12,734,408 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1812,703,341 - 12,734,479 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1812,347,573 - 12,378,642 (-)NCBI
ROS_Cfam_1.01812,974,872 - 13,005,942 (-)NCBI
UMICH_Zoey_3.11812,791,797 - 12,823,078 (-)NCBI
UNSW_CanFamBas_1.01812,712,079 - 12,743,105 (-)NCBI
UU_Cfam_GSD_1.01812,939,857 - 12,971,151 (-)NCBI
Dld
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511855,123,461 - 55,147,834 (-)NCBI
SpeTri2.0NW_00493647916,247,230 - 16,271,597 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9107,642,095 - 107,673,583 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19107,642,129 - 107,668,443 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29118,410,873 - 118,437,344 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DLD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12176,795,573 - 76,825,504 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2176,795,592 - 76,824,923 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604227,037,869 - 27,067,933 (-)NCBIVero_WHO_p1.0
Dld
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473921,842,897 - 21,873,334 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000009124   ⟹   ENSCLAP00000008996
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541012,212,963 - 12,238,561 (+)Ensembl
RefSeq Acc Id: XM_005377291   ⟹   XP_005377348
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541012,212,981 - 12,238,561 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013510668   ⟹   XP_013366122
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541012,213,907 - 12,238,561 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005377348 (Get FASTA)   NCBI Sequence Viewer  
  XP_013366122 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005377348   ⟸   XM_005377291
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013366122   ⟸   XM_013510668
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000008996   ⟸   ENSCLAT00000009124


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006284 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000008996 ENTREZGENE
Ensembl Transcript ENSCLAT00000009124 ENTREZGENE
NCBI Gene Dld ENTREZGENE