Sars1 (seryl-tRNA synthetase 1) - Rat Genome Database

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Gene: Sars1 (seryl-tRNA synthetase 1) Chinchilla lanigera
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Symbol: Sars1
Name: seryl-tRNA synthetase 1
RGD ID: 8749961
Description: ENCODES a protein that exhibits enzyme binding (ortholog); protein homodimerization activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of angiogenesis (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of vascular endothelial growth factor production (ortholog); PARTICIPATES IN dihydropyrimidine dehydrogenase deficiency pathway; dimethylglycine dehydrogenase deficiency pathway; nonketotic hyperglycinemia pathway; ASSOCIATED WITH arteriovenous malformations of the brain (ortholog); autistic disorder (ortholog); intellectual disability (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: Sars; serine--tRNA ligase, cytoplasmic; seryl-tRNA synthetase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543512,641,776 - 12,660,682 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543512,642,485 - 12,659,833 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)

References


Genomics

Comparative Map Data
Sars1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543512,641,776 - 12,660,682 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543512,642,485 - 12,659,833 (+)NCBIChiLan1.0ChiLan1.0
SARS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1109,213,918 - 109,238,182 (+)EnsemblGRCh38hg38GRCh38
GRCh381109,213,893 - 109,238,182 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371109,756,515 - 109,780,804 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361109,558,063 - 109,582,308 (+)NCBINCBI36hg18NCBI36
Build 341109,468,581 - 109,492,827NCBI
Celera1108,025,871 - 108,050,163 (+)NCBI
Cytogenetic Map1p13.3NCBI
HuRef1107,649,736 - 107,674,024 (+)NCBIHuRef
CHM1_11109,871,309 - 109,895,637 (+)NCBICHM1_1
Sars
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393108,332,180 - 108,352,575 (-)NCBIGRCm39mm39
GRCm39 Ensembl3108,332,181 - 108,352,525 (-)Ensembl
GRCm383108,424,864 - 108,445,259 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,424,865 - 108,445,209 (-)EnsemblGRCm38mm10GRCm38
MGSCv373108,229,530 - 108,248,087 (-)NCBIGRCm37mm9NCBIm37
MGSCv363108,554,668 - 108,573,225 (-)NCBImm8
Celera3110,760,829 - 110,779,384 (-)NCBICelera
Cytogenetic Map3F3NCBI
cM Map347.08NCBI
Sars1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22196,065,543 - 196,081,240 (-)NCBI
Rnor_6.0 Ensembl2211,219,750 - 211,235,467 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02211,219,743 - 211,235,475 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02230,689,709 - 230,705,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,995,537 - 204,011,262 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12203,960,370 - 203,964,749 (-)NCBI
Celera2188,711,760 - 188,728,010 (-)NCBICelera
Cytogenetic Map2q34NCBI
SARS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11110,755,241 - 110,779,616 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1110,755,054 - 110,779,704 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01111,590,850 - 111,615,068 (+)NCBIMhudiblu_PPA_v0panPan3
SARS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1642,584,792 - 42,605,201 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl642,584,798 - 42,605,136 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha645,359,499 - 45,379,900 (-)NCBI
ROS_Cfam_1.0642,916,110 - 42,936,514 (-)NCBI
UMICH_Zoey_3.1642,647,449 - 42,667,829 (-)NCBI
UNSW_CanFamBas_1.0642,605,509 - 42,625,891 (-)NCBI
UU_Cfam_GSD_1.0643,040,831 - 43,061,242 (-)NCBI
Sars1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505819,347,165 - 19,367,040 (-)NCBI
SpeTri2.0NW_004936704747,109 - 766,981 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SARS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4110,857,088 - 110,874,815 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14110,857,067 - 110,874,712 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24121,350,908 - 121,368,532 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103225885
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12024,303,741 - 24,321,931 (-)NCBI
Sars1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247724,963,173 - 4,978,294 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000007071   ⟹   ENSCLAP00000006959
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543512,641,776 - 12,660,682 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000007072   ⟹   ENSCLAP00000006960
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543512,641,776 - 12,660,682 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000007073   ⟹   ENSCLAP00000006961
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543512,642,586 - 12,657,943 (+)Ensembl
RefSeq Acc Id: XM_005388851   ⟹   XP_005388908
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543512,642,486 - 12,659,833 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013516442   ⟹   XP_013371896
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543512,642,485 - 12,659,833 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005388908 (Get FASTA)   NCBI Sequence Viewer  
  XP_013371896 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005388908   ⟸   XM_005388851
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013371896   ⟸   XM_013516442
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCLAP00000006961   ⟸   ENSCLAT00000007073
RefSeq Acc Id: ENSCLAP00000006960   ⟸   ENSCLAT00000007072
RefSeq Acc Id: ENSCLAP00000006959   ⟸   ENSCLAT00000007071


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004902 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000006959 ENTREZGENE
  ENSCLAP00000006960 ENTREZGENE
Ensembl Transcript ENSCLAT00000007071 ENTREZGENE
  ENSCLAT00000007072 ENTREZGENE
NCBI Gene Sars ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-23 Sars1  seryl-tRNA synthetase 1  Sars  seryl-tRNA synthetase  Symbol and/or name change 5135510 APPROVED