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Gene: Trir (telomerase RNA component interacting RNase) Chinchilla lanigera

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Symbol:

Trir

Name:

telomerase RNA component interacting RNase

RGD ID:

8745727

Description:

ENCODES a protein that exhibits 3'-5' exonuclease activity (ortholog); 5'-3' exonuclease activity (ortholog); INVOLVED IN rRNA catabolic process (ortholog); ASSOCIATED WITH Aicardi-Goutieres Syndrome 4 (ortholog); alpha-mannosidosis (ortholog); Charcot-Marie-Tooth disease dominant intermediate B (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

chromosome unknown open reading frame, human C19orf43; LOC102020242; uncharacterized protein C19orf43 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	31,831,093 - 31,834,796 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	31,831,093 - 31,834,796 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aicardi-Goutieres Syndrome 4 (ISO)

alpha-mannosidosis (ISO)

Charcot-Marie-Tooth disease dominant intermediate B (ISO)

episodic ataxia type 2 (ISO)

glutaric acidemia I (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

rRNA catabolic process (ISO)

Molecular Function

3'-5' exonuclease activity (ISO)

5'-3' exonuclease activity (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Trir
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	31,831,093 - 31,834,796 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	31,831,093 - 31,834,796 (-)	NCBI	ChiLan1.0	ChiLan1.0

TRIR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	12,730,640 - 12,734,684 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	12,730,640 - 12,734,684 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	12,841,454 - 12,845,498 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	12,702,454 - 12,706,529 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	12,731,165 - 12,735,240 (-)	NCBI		Celera
Cytogenetic Map	19	p13.13	NCBI
HuRef	19	12,414,575 - 12,418,651 (-)	NCBI		HuRef
CHM1_1	19	12,841,916 - 12,845,991 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	12,855,132 - 12,859,177 (-)	NCBI		T2T-CHM13v2.0

Trir
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	85,753,440 - 85,756,920 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	85,753,452 - 85,756,915 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	85,026,811 - 85,030,291 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	85,026,823 - 85,030,286 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	87,550,732 - 87,554,185 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	87,916,938 - 87,920,391 (+)	NCBI		MGSCv36	mm8
Celera	8	89,321,614 - 89,325,063 (+)	NCBI		Celera
Cytogenetic Map	8	C3	NCBI
cM Map	8	41.49	NCBI

Trir
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	40,029,952 - 40,033,368 (-)	NCBI		GRCr8
mRatBN7.2	19	23,125,083 - 23,128,502 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	23,125,083 - 23,128,510 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	29,947,673 - 29,951,092 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	30,602,037 - 30,605,456 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	32,824,721 - 32,828,140 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	26,142,720 - 26,146,136 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	26,142,720 - 26,146,136 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	37,118,343 - 37,121,759 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	24,781,364 - 24,784,781 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	19	22,683,041 - 22,686,457 (-)	NCBI		Celera
Cytogenetic Map	19	q11	NCBI

TRIR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	17,660,322 - 17,664,443 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	16,660,873 - 16,665,206 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	12,293,236 - 12,297,338 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	13,038,516 - 13,045,720 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	13,038,837 - 13,046,866 (-)	Ensembl	panpan1.1		panPan2

TRIR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	49,400,082 - 49,403,533 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	49,400,179 - 49,403,530 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	49,273,689 - 49,277,140 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	49,918,506 - 49,921,957 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	49,918,604 - 49,921,955 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	49,129,578 - 49,133,027 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	49,555,921 - 49,559,367 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	49,798,588 - 49,802,039 (+)	NCBI		UU_Cfam_GSD_1.0

Trir
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	208,504,180 - 208,507,641 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936659	1,846,541 - 1,850,565 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936659	1,847,065 - 1,850,557 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	66,262,424 - 66,265,426 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	66,262,377 - 66,265,427 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	66,642,986 - 66,646,027 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	11,419,982 - 11,424,075 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	11,419,938 - 11,424,062 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	8,372,575 - 8,376,706 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trir
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624901	356,151 - 360,001 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005381022	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01016698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01012972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000016390 ⟹ ENSCLAP00000016226

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955415	31,831,093 - 31,834,796 (-)	Ensembl

RefSeq Acc Id:

XM_005381022 ⟹ XP_005381079

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955415	31,831,093 - 31,834,796 (-)	NCBI

Sequence:

show sequence

GGACGCTGCTAGTCGGGCGCCAAACGCGGGGCTGGAGCGCACTTCCCGGAGTCCTTTGCGCGGC
ACCTGGCGACAAAATGGCTGCCCGAGGGAGACGGGCGGAGCCTCCGGGCCGGGAGGCGCCAGGC
CCTGCGGGCGGCGGCGGTAGTCGATGGGCTGAGTCGGGGCCTGGGACGTCACCCGAGAGCGGGG
ACGAGGATGTGTCGGGCGCAGGTTCGAGCCCGGTGTCAGGCGGCGTGAACTTGTTCGCCAACGA
CGGCAGCTTCCTGGAGCTGTTCAAGCGGAAGATGGAGGAGGAGCAGCGGCAGCGGCAGGAGGAG
CCGCCCCCGGGCTCGCAGCGACCCGACCAGCCGGCCGCCGCCGCCCCGGGCCCCGGGGGCCCGA
AGAGGAAGGGCGGCCCGGGCCCCACACTCAGCTTCGTGGGCAAACGCAGAGGCGGGAACAAACT
AGCCCTCAAGACGGGAATAGTAGCCAAGAAGCAGAAGACGGAGGATGAGGTATTAACAAGTAAA
GGTGACGCATGGGCCAAGTACATGGCAGAAGTGAAAAAGTACAAAGCCCACCAGTGCGGTGATG
ATGATAAAACTCGGCCCCTGGTGAAATGAGCCCCCTCCCTGCGTGCCCAGGGCTGGGACTCTGC
GATGTACATAACTATTTAATGCGGCGGCGGTGGCAGCGGCGGCCTTCCCCCCCGAGGACTGATT
CACAGAAGGAAACCGAGGTGCTTCCCGCGGCCGCGGATGATTCTCCAGGACTCTTTTTTTACCT
TGAGCACTTGCCTCCTGAGACTTACTAGAACAGTGGTTTACTGTCCCCTCTCTTCCACCTTCTC
ACTCTCTCTGGCTCTTTCTATCTTCCTTTTCTTGCCTTCCTCTCCCCGCCCTTAGCCATCACTT
CTGGGAAGTAAAAAACCTGATTTAGTGCGGGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005381079	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000016226
	ENSCLAP00000016226.1

RefSeq Acc Id:	XP_005381079 ⟸ XM_005381022
- UniProtKB:	A0A8C2VIJ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAARGRRAEPPGREAPGPAGGGGSRWAESGPGTSPESGDEDVSGAGSSPVSGGVNLFANDGSFL ELFKRKMEEEQRQRQEEPPPGSQRPDQPAAAAPGPGGPKRKGGPGPTLSFVGKRRGGNKLALKT GIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK hide sequence

Ensembl Acc Id:

ENSCLAP00000016226 ⟸ ENSCLAT00000016390

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000011164	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000016390	ENTREZGENE
	ENSCLAT00000016390.1	UniProtKB/TrEMBL
InterPro	TRIR	UniProtKB/TrEMBL
NCBI Gene	LOC102020242	ENTREZGENE
PANTHER	PTHR34753	UniProtKB/TrEMBL
	TELOMERASE RNA COMPONENT INTERACTING RNASE	UniProtKB/TrEMBL
UniProt	A0A8C2VIJ4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-05-30	Trir	telomerase RNA component interacting RNase	LOC102020242	chromosome unknown open reading frame, human C19orf43	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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