Krt2 (keratin 2) - Rat Genome Database

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Gene: Krt2 (keratin 2) Chinchilla lanigera
Analyze
Symbol: Krt2
Name: keratin 2
RGD ID: 8745539
Description: ENCODES a protein that exhibits cytoskeletal protein binding (ortholog); structural constituent of skin epidermis (ortholog); INVOLVED IN epidermis development (ortholog); intermediate filament organization (ortholog); keratinization (ortholog); ASSOCIATED WITH bullous congenital ichthyosiform erythroderma (ortholog); contact dermatitis (ortholog); genetic disease (ortholog); FOUND IN cornified envelope (ortholog); cytoplasm (ortholog); keratin filament (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: keratin 2, type II; keratin, type II cytoskeletal 2 epidermal
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555473,027,767 - 3,035,244 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555473,027,767 - 3,035,244 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Krt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555473,027,767 - 3,035,244 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555473,027,767 - 3,035,244 (-)NCBIChiLan1.0ChiLan1.0
KRT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381252,644,558 - 52,652,211 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1252,644,558 - 52,652,211 (-)EnsemblGRCh38hg38GRCh38
GRCh371253,038,342 - 53,045,995 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,324,609 - 51,332,226 (-)NCBINCBI36Build 36hg18NCBI36
Build 341251,324,609 - 51,332,226NCBI
Celera1252,684,582 - 52,692,199 (-)NCBICelera
Cytogenetic Map12q13.13NCBI
HuRef1250,082,187 - 50,089,804 (-)NCBIHuRef
CHM1_11253,005,187 - 53,012,804 (-)NCBICHM1_1
T2T-CHM13v2.01252,609,117 - 52,616,770 (-)NCBIT2T-CHM13v2.0
Krt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,719,124 - 101,727,391 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl15101,719,124 - 101,726,604 (-)EnsemblGRCm39 Ensembl
GRCm3815101,810,689 - 101,818,956 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15101,810,689 - 101,818,169 (-)EnsemblGRCm38mm10GRCm38
MGSCv3715101,641,120 - 101,648,600 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3615101,638,733 - 101,646,169 (-)NCBIMGSCv36mm8
Celera15103,963,224 - 103,970,674 (-)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.03NCBI
Krt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87134,819,584 - 134,826,736 (-)NCBIGRCr8
mRatBN7.27132,940,879 - 132,948,031 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7132,940,862 - 132,947,963 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7134,702,372 - 134,709,508 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07136,931,896 - 136,939,028 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07136,910,509 - 136,917,679 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07143,412,858 - 143,420,463 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,412,858 - 143,420,027 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,211,053 - 141,218,655 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47140,500,902 - 140,507,590 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17140,577,338 - 140,584,027 (-)NCBI
Celera7129,381,180 - 129,387,868 (-)NCBICelera
Cytogenetic Map7q36NCBI
KRT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21041,544,450 - 41,552,120 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11241,541,213 - 41,548,883 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01236,111,978 - 36,119,684 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11236,889,586 - 36,897,274 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,889,619 - 36,896,813 (+)Ensemblpanpan1.1panPan2
KRT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1272,447,854 - 2,454,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2743,799,509 - 43,806,126 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,447,655 - 2,454,776 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1272,463,994 - 2,470,611 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,449,101 - 2,455,769 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02744,197,879 - 44,204,549 (-)NCBIUU_Cfam_GSD_1.0
Krt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494563,103,733 - 63,110,578 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651210,054,708 - 10,061,021 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651210,054,708 - 10,061,021 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl517,984,316 - 17,992,092 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1517,984,316 - 17,992,092 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,425,807 - 18,485,348 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11148,780,378 - 48,789,540 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1148,780,388 - 48,788,085 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037197,284,151 - 197,291,922 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Krt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624904761,073 - 768,153 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624904760,957 - 768,153 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000001410   ⟹   ENSCLAP00000001368
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555473,027,767 - 3,035,244 (-)Ensembl
RefSeq Acc Id: XM_005411955   ⟹   XP_005412012
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555473,027,767 - 3,035,244 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005412012 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000001368
  ENSCLAP00000001368.1
RefSeq Acc Id: XP_005412012   ⟸   XM_005411955
- UniProtKB: A0A8C2UPM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000001368   ⟸   ENSCLAT00000001410
Protein Domains
IF rod


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001040 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001410 ENTREZGENE
  ENSCLAT00000001410.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  Single helix bin UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro IF_conserved UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/TrEMBL
  Keratin_2_head UniProtKB/TrEMBL
  Keratin_II UniProtKB/TrEMBL
NCBI Gene Krt2 ENTREZGENE
PANTHER GATA-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  KERATIN, TYPE II CYTOSKELETAL 2 EPIDERMAL UniProtKB/TrEMBL
Pfam Filament UniProtKB/TrEMBL
  Keratin_2_head UniProtKB/TrEMBL
PRINTS TYPE2KERATIN UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/TrEMBL
SMART Filament UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/TrEMBL
UniProt A0A8C2UPM5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Krt2  keratin 2    keratin 2, type II  Symbol and/or name change 5135510 APPROVED
2015-08-25 Krt2  keratin 2, type II    keratin 2  Symbol and/or name change 5135510 APPROVED