Nhp2 (NHP2 ribonucleoprotein) - Rat Genome Database

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Gene: Nhp2 (NHP2 ribonucleoprotein) Chinchilla lanigera
Analyze
Symbol: Nhp2
Name: NHP2 ribonucleoprotein
RGD ID: 8743587
Description: ENCODES a protein that exhibits box H/ACA snoRNA binding (ortholog); mRNA 3'-UTR binding (ortholog); RNA binding (ortholog); INVOLVED IN positive regulation of telomerase RNA localization to Cajal body (ortholog); snoRNA guided rRNA pseudouridine synthesis (ortholog); telomere maintenance via telomerase (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH Autosomal Recessive Dyskeratosis Congenita (ortholog); autosomal recessive dyskeratosis congenita 1 (ortholog); autosomal recessive dyskeratosis congenita 2 (ortholog); FOUND IN box H/ACA snoRNP complex (ortholog); box H/ACA telomerase RNP complex (ortholog); telomerase holoenzyme complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: H/ACA ribonucleoprotein complex subunit 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554082,090,772 - 2,094,453 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554082,090,772 - 2,094,453 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nhp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554082,090,772 - 2,094,453 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554082,090,772 - 2,094,453 (+)NCBIChiLan1.0ChiLan1.0
NHP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385178,149,463 - 178,153,885 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5178,149,463 - 178,153,894 (-)EnsemblGRCh38hg38GRCh38
GRCh375177,576,464 - 177,580,886 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365177,509,070 - 177,513,567 (-)NCBINCBI36Build 36hg18NCBI36
Build 345177,509,073 - 177,513,567NCBI
Celera5173,203,446 - 173,207,943 (-)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5172,302,433 - 172,306,930 (-)NCBIHuRef
CHM1_15177,007,842 - 177,012,339 (-)NCBICHM1_1
T2T-CHM13v2.05178,699,722 - 178,704,144 (-)NCBIT2T-CHM13v2.0
Nhp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,510,600 - 51,514,545 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,510,562 - 51,514,541 (+)EnsemblGRCm39 Ensembl
GRCm381151,619,773 - 51,623,718 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,619,735 - 51,623,714 (+)EnsemblGRCm38mm10GRCm38
MGSCv371151,433,275 - 51,437,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361151,463,196 - 51,467,137 (+)NCBIMGSCv36mm8
Celera1156,191,112 - 56,195,057 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.14NCBI
Nhp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81036,378,020 - 36,381,362 (+)NCBIGRCr8
mRatBN7.21035,877,057 - 35,880,399 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1035,877,054 - 35,882,545 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx363,415,455 - 63,415,690 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0371,999,106 - 71,999,341 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.01034,975,701 - 34,979,082 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1034,975,708 - 34,979,082 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,069,344 - 37,072,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,841,672 - 36,845,050 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,137,277 - 37,140,651 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1035,233,774 - 35,237,148 (+)NCBICelera
Cytogenetic Map10q22NCBI
NHP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24173,090,862 - 173,095,371 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15171,230,398 - 171,234,909 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05173,308,560 - 173,313,046 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15180,566,008 - 180,570,502 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5180,566,008 - 180,570,502 (-)Ensemblpanpan1.1panPan2
NHP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,389,549 - 3,393,010 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,389,591 - 3,395,313 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha113,532,480 - 3,535,984 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0113,365,217 - 3,368,723 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl113,365,309 - 3,368,720 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1113,335,883 - 3,337,251 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0113,413,347 - 3,416,848 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,654,898 - 3,659,015 (+)NCBIUU_Cfam_GSD_1.0
Nhp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213113,517,778 - 113,522,464 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936647520,494 - 525,226 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936647520,542 - 525,226 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NHP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1280,223,439 - 80,227,614 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2281,839,915 - 81,844,092 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NHP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12379,842,690 - 79,847,138 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2379,842,948 - 79,846,984 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607511,143,336 - 11,147,779 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nhp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473341,371,897 - 41,375,363 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473341,371,897 - 41,375,360 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023560   ⟹   ENSCLAP00000023339
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554082,090,772 - 2,094,453 (+)Ensembl
RefSeq Acc Id: XM_005376038   ⟹   XP_005376095
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554082,090,772 - 2,094,453 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005376095 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000023339
  ENSCLAP00000023339.1
Reference Protein Sequences
RefSeq Acc Id: XP_005376095   ⟸   XM_005376038
- UniProtKB: A0A8C2W2L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000023339   ⟸   ENSCLAT00000023560
Protein Domains
Ribosomal protein eL8/eL30/eS12/Gadd45


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016005 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000023560 ENTREZGENE
  ENSCLAT00000023560.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1330.30 UniProtKB/TrEMBL
InterPro H/ACA_rnp_Nhp2-like UniProtKB/TrEMBL
  L30e-like UniProtKB/TrEMBL
  Ribosomal_L7Ae/L30e/S12e/Gad45 UniProtKB/TrEMBL
  Ribosomal_L7Ae/L8/Nhp2 UniProtKB/TrEMBL
NCBI Gene Nhp2 ENTREZGENE
PANTHER H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 UniProtKB/TrEMBL
  RIBOSOMAL PROTEIN L7AE FAMILY MEMBER UniProtKB/TrEMBL
Pfam Ribosomal_L7Ae UniProtKB/TrEMBL
PRINTS L7ARS6FAMILY UniProtKB/TrEMBL
  NUCLEARHMG UniProtKB/TrEMBL
Superfamily-SCOP SSF55315 UniProtKB/TrEMBL
UniProt A0A8C2W2L8 ENTREZGENE, UniProtKB/TrEMBL