Setd7 (SET domain containing 7, histone lysine methyltransferase) - Rat Genome Database

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Gene: Setd7 (SET domain containing 7, histone lysine methyltransferase) Chinchilla lanigera
Analyze
Symbol: Setd7
Name: SET domain containing 7, histone lysine methyltransferase
RGD ID: 8743051
Description: ENCODES a protein that exhibits chromatin binding (ortholog); histone H3 methyltransferase activity (ortholog); histone methyltransferase activity (ortholog); INVOLVED IN chromatin organization (ortholog); DNA damage response (ortholog); heterochromatin organization (ortholog); PARTICIPATES IN carnitine biosynthetic pathway; histone modification pathway; methionine cycle/metabolic pathway; ASSOCIATED WITH cognitive disorder (ortholog); extrahepatic cholestasis (ortholog); fetal alcohol spectrum disorder (ortholog); FOUND IN chromosome (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histone-lysine N-methyltransferase SETD7; SET domain containing (lysine methyltransferase) 7; SET domain containing 7, lysine methyltransferase; SET domain containing lysine methyltransferase 7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554284,131,103 - 4,178,250 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554284,131,431 - 4,178,250 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (ISO)
nucleolus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Setd7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554284,131,103 - 4,178,250 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554284,131,431 - 4,178,250 (+)NCBIChiLan1.0ChiLan1.0
SETD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384139,492,974 - 139,556,219 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4139,495,941 - 139,606,699 (-)EnsemblGRCh38hg38GRCh38
GRCh374140,414,128 - 140,477,373 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364140,646,642 - 140,697,027 (-)NCBINCBI36Build 36hg18NCBI36
Celera4137,759,367 - 137,809,746 (-)NCBICelera
Cytogenetic Map4q31.1NCBI
HuRef4136,156,561 - 136,206,720 (-)NCBIHuRef
CHM1_14140,404,455 - 140,454,786 (-)NCBICHM1_1
T2T-CHM13v2.04142,812,640 - 142,875,826 (-)NCBIT2T-CHM13v2.0
Setd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39351,422,740 - 51,468,519 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl351,422,740 - 51,468,300 (-)EnsemblGRCm39 Ensembl
GRCm38351,515,318 - 51,560,823 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl351,515,319 - 51,560,879 (-)EnsemblGRCm38mm10GRCm38
MGSCv37351,319,240 - 51,364,745 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36351,603,247 - 51,648,752 (-)NCBIMGSCv36mm8
Celera351,246,288 - 51,292,035 (-)NCBICelera
Cytogenetic Map3CNCBI
cM Map322.5NCBI
Setd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82137,713,545 - 137,756,319 (-)NCBIGRCr8
mRatBN7.22135,562,683 - 135,605,468 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2135,562,683 - 135,605,468 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2142,138,563 - 142,181,343 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02140,250,828 - 140,293,610 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02134,882,909 - 134,925,676 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02140,576,188 - 140,618,405 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2140,576,188 - 140,618,405 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02160,051,126 - 160,093,343 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42140,413,802 - 140,456,579 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2130,058,161 - 130,100,836 (-)NCBICelera
Cytogenetic Map2q26NCBI
SETD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23137,379,578 - 137,432,801 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14137,756,847 - 137,825,326 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04131,869,999 - 131,921,342 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14143,167,190 - 143,227,731 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4143,167,190 - 143,227,732 (-)Ensemblpanpan1.1panPan2
SETD7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,186,620 - 3,229,305 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,186,906 - 3,224,113 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha193,427,673 - 3,478,217 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0193,250,127 - 3,300,591 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl193,250,143 - 3,298,678 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,182,575 - 3,232,096 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,543,515 - 3,593,766 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,907,163 - 3,957,479 (+)NCBIUU_Cfam_GSD_1.0
Setd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530150,657,144 - 50,705,771 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365358,094,178 - 8,137,580 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365358,094,479 - 8,143,108 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SETD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl887,478,173 - 87,527,188 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1887,478,266 - 87,527,190 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2893,131,742 - 93,168,617 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SETD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1786,476,101 - 86,528,146 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl786,481,726 - 86,527,779 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603765,998,142 - 66,050,297 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Setd7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477719,768,698 - 19,814,506 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477719,764,383 - 19,812,804 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000007779   ⟹   ENSCLAP00000007660
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554284,131,103 - 4,178,250 (+)Ensembl
RefSeq Acc Id: XM_005386687   ⟹   XP_005386744
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554284,131,431 - 4,178,250 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005386744 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007660
  ENSCLAP00000007660.1
Reference Protein Sequences
RefSeq Acc Id: XP_005386744   ⟸   XM_005386687
- UniProtKB: A0A8C2V266 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007660   ⟸   ENSCLAT00000007779
Protein Domains
SET


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005370 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007779 ENTREZGENE
  ENSCLAT00000007779.1 UniProtKB/TrEMBL
Gene3D-CATH 2.170.270.10 UniProtKB/TrEMBL
  Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain UniProtKB/TrEMBL
InterPro Hist-Lys_N-MeTrfase_SET UniProtKB/TrEMBL
  MORN UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  SETD7_SET UniProtKB/TrEMBL
NCBI Gene Setd7 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SETD7 UniProtKB/TrEMBL
Pfam MORN UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
PIRSF Histone_Lys_mtfrase_SET UniProtKB/TrEMBL
PROSITE SAM_MT43_SET7 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
Superfamily-SCOP Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain UniProtKB/TrEMBL
  SSF82199 UniProtKB/TrEMBL
UniProt A0A8C2V266 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-01 Setd7  SET domain containing 7, histone lysine methyltransferase    SET domain containing 7, lysine methyltransferase  Symbol and/or name change 5135510 APPROVED
2018-12-25 Setd7  SET domain containing 7, lysine methyltransferase    SET domain containing lysine methyltransferase 7  Symbol and/or name change 5135510 APPROVED
2016-08-03 Setd7  SET domain containing lysine methyltransferase 7    SET domain containing (lysine methyltransferase) 7  Symbol and/or name change 5135510 APPROVED