Vps33a (VPS33A core subunit of CORVET and HOPS complexes) - Rat Genome Database

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Gene: Vps33a (VPS33A core subunit of CORVET and HOPS complexes) Chinchilla lanigera
Analyze
Symbol: Vps33a
Name: VPS33A core subunit of CORVET and HOPS complexes
RGD ID: 8742778
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); endosome to lysosome transport (ortholog); lysosome localization (ortholog); ASSOCIATED WITH genetic disease (ortholog); Hermansky-Pudlak syndrome (ortholog); Mucopolysaccharidosis-Plus Syndrome (ortholog); FOUND IN AP-3 adaptor complex (ortholog); autophagosome (ortholog); clathrin complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vacuolar protein sorting 33 homolog A (S. cerevisiae); vacuolar protein sorting-associated protein 33A; VPS33A, CORVET/HOPS core subunit
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,332,366 - 6,353,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,333,282 - 6,352,369 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Vps33a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554826,332,366 - 6,353,834 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554826,333,282 - 6,352,369 (+)NCBIChiLan1.0ChiLan1.0
VPS33A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812122,229,564 - 122,266,494 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12122,229,564 - 122,266,494 (-)EnsemblGRCh38hg38GRCh38
GRCh3712122,714,111 - 122,751,041 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612121,282,047 - 121,317,021 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412121,240,974 - 121,275,897NCBI
Celera12122,305,460 - 122,340,912 (-)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12119,676,859 - 119,711,913 (-)NCBIHuRef
CHM1_112122,684,386 - 122,719,360 (-)NCBICHM1_1
T2T-CHM13v2.012122,225,350 - 122,262,283 (-)NCBIT2T-CHM13v2.0
Vps33a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395123,666,820 - 123,711,104 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5123,666,722 - 123,711,101 (-)EnsemblGRCm39 Ensembl
GRCm385123,528,757 - 123,573,043 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5123,528,659 - 123,573,038 (-)EnsemblGRCm38mm10GRCm38
MGSCv375123,978,766 - 124,023,024 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365123,789,720 - 123,833,624 (-)NCBIMGSCv36mm8
Celera5120,615,562 - 120,647,244 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map563.03NCBI
Vps33a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81238,685,484 - 38,710,668 (+)NCBIGRCr8
mRatBN7.21233,024,596 - 33,051,399 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1233,024,650 - 33,051,393 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1234,203,080 - 34,228,179 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01234,814,434 - 34,839,530 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01233,866,322 - 33,891,419 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01238,459,816 - 38,482,903 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1238,459,832 - 38,484,512 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01240,340,915 - 40,364,786 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41234,163,538 - 34,189,019 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11234,026,939 - 34,054,016 (+)NCBI
Celera1234,710,002 - 34,735,096 (+)NCBICelera
Cytogenetic Map12q16NCBI
VPS33A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210130,322,804 - 130,358,825 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112130,319,726 - 130,354,330 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012119,831,693 - 119,868,132 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112123,200,964 - 123,236,132 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12123,201,663 - 123,236,019 (-)Ensemblpanpan1.1panPan2
VPS33A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1267,090,669 - 7,119,913 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha267,250,848 - 7,282,200 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0267,342,147 - 7,373,504 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl267,342,183 - 7,373,504 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1267,274,298 - 7,305,672 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,365,289 - 7,396,615 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,320,923 - 7,352,308 (+)NCBIUU_Cfam_GSD_1.0
Vps33a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118157,221,701 - 157,252,173 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365582,227,253 - 2,257,722 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365582,227,305 - 2,257,725 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS33A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1430,469,070 - 30,495,470 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11430,469,003 - 30,496,626 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21432,196,959 - 32,221,702 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VPS33A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111117,585,325 - 117,618,713 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11117,582,781 - 117,615,743 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037127,711,627 - 127,745,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vps33a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474722,461,346 - 22,478,867 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474722,458,098 - 22,478,735 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000016177   ⟹   ENSCLAP00000016013
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554826,332,366 - 6,353,834 (+)Ensembl
RefSeq Acc Id: XM_005403095   ⟹   XP_005403152
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554826,333,284 - 6,352,369 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005403096   ⟹   XP_005403153
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554826,333,282 - 6,349,389 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005403152 (Get FASTA)   NCBI Sequence Viewer  
  XP_005403153 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000016013
  ENSCLAP00000016013.1
Reference Protein Sequences
RefSeq Acc Id: XP_005403153   ⟸   XM_005403096
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005403152   ⟸   XM_005403095
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VII2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000016013   ⟸   ENSCLAT00000016177


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011023 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016177 ENTREZGENE
  ENSCLAT00000016177.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.850 UniProtKB/TrEMBL
  3.40.50.1910 UniProtKB/TrEMBL
  3.40.50.2060 UniProtKB/TrEMBL
InterPro Sec-1-like_dom1 UniProtKB/TrEMBL
  Sec1-like UniProtKB/TrEMBL
  Sec1-like_dom2 UniProtKB/TrEMBL
  Sec1-like_sf UniProtKB/TrEMBL
  VPS33_dom3b UniProtKB/TrEMBL
NCBI Gene Vps33a ENTREZGENE
PANTHER PTHR11679 UniProtKB/TrEMBL
  VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A UniProtKB/TrEMBL
Pfam Sec1 UniProtKB/TrEMBL
Superfamily-SCOP SSF56815 UniProtKB/TrEMBL
UniProt A0A8C2VII2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Vps33a  VPS33A core subunit of CORVET and HOPS complexes    VPS33A, CORVET/HOPS core subunit  Symbol and/or name change 5135510 APPROVED
2016-08-16 Vps33a  VPS33A, CORVET/HOPS core subunit    vacuolar protein sorting 33 homolog A (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED