Vcp (valosin containing protein) - Rat Genome Database

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Gene: Vcp (valosin containing protein) Chinchilla lanigera
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Symbol: Vcp
Name: valosin containing protein
RGD ID: 8742272
Description: ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATP hydrolysis activity (ortholog); INVOLVED IN activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); aggresome assembly (ortholog); ATP metabolic process (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); FOUND IN ATPase complex (ortholog); cytoplasm (ortholog); cytoplasmic stress granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: transitional endoplasmic reticulum ATPase
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554721,107,164 - 1,124,076 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554721,111,649 - 1,124,076 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
aggresome assembly  (ISO)
ATP metabolic process  (ISO)
autophagosome maturation  (ISO)
autophagy  (ISO)
cellular response to arsenite ion  (ISO)
cellular response to DNA damage stimulus  (ISO)
cellular response to heat  (ISO)
double-strand break repair  (ISO)
endoplasmic reticulum stress-induced pre-emptive quality control  (ISO)
endoplasmic reticulum to Golgi vesicle-mediated transport  (ISO)
endosome to lysosome transport via multivesicular body sorting pathway  (ISO)
ER-associated misfolded protein catabolic process  (ISO)
ERAD pathway  (ISO)
flavin adenine dinucleotide catabolic process  (ISO)
macroautophagy  (ISO)
NADH metabolic process  (ISO)
negative regulation of smoothened signaling pathway  (ISO)
positive regulation of ATP biosynthetic process  (ISO)
positive regulation of canonical Wnt signaling pathway  (ISO)
positive regulation of Lys63-specific deubiquitinase activity  (ISO)
positive regulation of mitochondrial membrane potential  (ISO)
positive regulation of oxidative phosphorylation  (ISO)
positive regulation of proteasomal ubiquitin-dependent protein catabolic process  (ISO)
positive regulation of protein catabolic process  (ISO)
positive regulation of protein K63-linked deubiquitination  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of ubiquitin-dependent protein catabolic process  (ISO)
proteasomal protein catabolic process  (ISO)
proteasome-mediated ubiquitin-dependent protein catabolic process  (ISO)
protein ubiquitination  (ISO)
protein-DNA covalent cross-linking repair  (ISO)
regulation of aerobic respiration  (ISO)
regulation of protein localization to chromatin  (ISO)
regulation of synapse organization  (ISO)
retrograde protein transport, ER to cytosol  (ISO)
stress granule disassembly  (ISO)
translesion synthesis  (ISO)
ubiquitin-dependent ERAD pathway  (ISO)
ubiquitin-dependent protein catabolic process  (ISO)
viral genome replication  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Vcp
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554721,107,164 - 1,124,076 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554721,111,649 - 1,124,076 (+)NCBIChiLan1.0ChiLan1.0
VCP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl935,053,928 - 35,072,668 (-)EnsemblGRCh38hg38GRCh38
GRCh38935,056,064 - 35,072,625 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37935,056,061 - 35,072,622 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,046,560 - 35,062,564 (-)NCBINCBI36hg18NCBI36
Build 34935,046,560 - 35,062,564NCBI
Celera934,988,041 - 35,004,706 (-)NCBI
Cytogenetic Map9p13.3NCBI
HuRef935,011,651 - 35,028,327 (-)NCBIHuRef
CHM1_1935,055,907 - 35,072,605 (-)NCBICHM1_1
Vcp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39442,979,964 - 43,000,507 (-)NCBIGRCm39mm39
GRCm39 Ensembl442,979,963 - 43,000,507 (-)Ensembl
GRCm38442,979,964 - 43,000,507 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl442,979,963 - 43,000,507 (-)EnsemblGRCm38mm10GRCm38
MGSCv37442,992,836 - 43,013,379 (-)NCBIGRCm37mm9NCBIm37
MGSCv36443,001,064 - 43,021,534 (-)NCBImm8
Celera443,010,123 - 43,030,659 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map422.95NCBI
Vcp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2557,210,167 - 57,229,571 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl557,210,168 - 57,229,571 (-)Ensembl
Rnor_6.0558,426,548 - 58,445,953 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,426,549 - 58,445,953 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0562,951,999 - 62,971,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,472,100 - 59,491,508 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1559,472,279 - 59,491,687 (-)NCBI
Celera555,799,589 - 55,818,873 (-)NCBICelera
Cytogenetic Map5q22NCBI
VCP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1935,712,937 - 35,729,588 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl935,712,937 - 35,729,588 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0934,907,147 - 34,923,227 (-)NCBIMhudiblu_PPA_v0panPan3
VCP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,636,986 - 51,651,749 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1151,637,411 - 51,651,714 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,205,792 - 50,220,556 (-)NCBI
ROS_Cfam_1.01152,702,444 - 52,717,215 (-)NCBI
UMICH_Zoey_3.11151,246,536 - 51,261,297 (-)NCBI
UNSW_CanFamBas_1.01151,231,677 - 51,246,443 (-)NCBI
UU_Cfam_GSD_1.01151,933,494 - 51,948,301 (-)NCBI
LOC101972576
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947166,538,385 - 166,554,770 (-)NCBI
SpeTri2.0NW_0049365243,085,959 - 3,102,461 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VCP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1235,796,446 - 235,876,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11235,854,532 - 235,869,712 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,379,929 - 263,394,992 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103219235
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11245,545,139 - 45,560,702 (+)NCBI
ChlSab1.1 Ensembl1245,545,507 - 45,563,380 (+)Ensembl
Vero_WHO_p1.0NW_02366603842,661,397 - 42,677,470 (+)NCBI
Vcp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624915253,240 - 270,440 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000003976   ⟹   ENSCLAP00000003900
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554721,107,164 - 1,124,076 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000003977   ⟹   ENSCLAP00000003901
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554721,110,782 - 1,123,524 (+)Ensembl
RefSeq Acc Id: XM_005401031   ⟹   XP_005401088
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554721,111,649 - 1,124,076 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005401088 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005401088   ⟸   XM_005401031
- Sequence:
RefSeq Acc Id: ENSCLAP00000003901   ⟸   ENSCLAT00000003977
RefSeq Acc Id: ENSCLAP00000003900   ⟸   ENSCLAT00000003976


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000002773 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000003900 ENTREZGENE
Ensembl Transcript ENSCLAT00000003976 ENTREZGENE
NCBI Gene Vcp ENTREZGENE