Il19 (interleukin 19) - Rat Genome Database

Name: Il19
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Il19 (interleukin 19) Chinchilla lanigera

Analyze

Symbol:

Il19

Name:

interleukin 19

RGD ID:

8739150

Description:

INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway (ortholog); negative regulation of low-density lipoprotein particle clearance (ortholog); positive regulation of apoptotic signaling pathway (ortholog); PARTICIPATES IN interleukin-23 signaling pathway; ASSOCIATED WITH asthma (ortholog); autistic disorder (ortholog); B-Cell Chronic Lymphocytic Leukemia (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

interleukin-19

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IL19 (interleukin 19)	NCBI	Ortholog
Mus musculus (house mouse):	Il19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Il19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IL19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IL19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Il19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IL19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IL19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Il19 (interleukin 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	42,376,104 - 42,384,902 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	42,376,102 - 42,384,902 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

autistic disorder (ISO)

B-Cell Chronic Lymphocytic Leukemia (ISO)

cholangiocarcinoma (ISO)

chronic kidney disease (ISO)

common variable immunodeficiency 7 (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

graft-versus-host disease (ISO)

human immunodeficiency virus infectious disease (ISO)

Hypokalemic Periodic Paralysis, Type 1 (ISO)

inflammatory bowel disease (ISO)

leprosy (ISO)

parathyroid carcinoma (ISO)

periodontal disease (ISO)

rheumatoid arthritis (ISO)

toxic shock syndrome (ISO)

type 1 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of extrinsic apoptotic signaling pathway (ISO)

negative regulation of low-density lipoprotein particle clearance (ISO)

positive regulation of apoptotic signaling pathway (ISO)

positive regulation of intrinsic apoptotic signaling pathway (ISO)

reactive oxygen species metabolic process (ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

interleukin-23 signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data

Il19
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	42,376,104 - 42,384,902 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	42,376,102 - 42,384,902 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL19
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	206,770,773 - 206,842,981 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	206,770,764 - 206,842,981 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	206,944,118 - 207,016,326 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	205,038,838 - 205,082,948 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	203,360,609 - 203,404,719	NCBI
Celera	1	180,223,655 - 180,267,841 (+)	NCBI		Celera
Cytogenetic Map	1	q32.1	NCBI
HuRef	1	177,670,510 - 177,714,575 (+)	NCBI		HuRef
CHM1_1	1	208,244,767 - 208,288,882 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	206,034,974 - 206,107,261 (+)	NCBI		T2T-CHM13v2.0

Il19
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	130,860,393 - 130,873,194 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	130,860,393 - 130,867,852 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	130,932,656 - 130,945,457 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	130,932,656 - 130,940,115 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	132,829,233 - 132,835,818 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	132,760,202 - 132,766,787 (-)	NCBI		MGSCv36	mm8
Celera	1	133,555,187 - 133,561,772 (-)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	56.89	NCBI

Il19
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	44,949,989 - 44,958,714 (-)	NCBI		GRCr8
mRatBN7.2	13	42,397,715 - 42,411,637 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	42,399,138 - 42,405,473 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	13	47,663,592 - 47,677,869 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	47,664,080 - 47,670,407 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	52,751,661 - 52,758,048 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	43,878,668 - 43,885,001 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	13	42,747,840 - 42,762,111 (-)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

IL19
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	42,531,737 - 42,556,495 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	42,497,692 - 42,522,458 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	182,372,339 - 182,446,147 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	186,680,606 - 186,724,748 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	186,651,640 - 186,724,748 (+)	Ensembl	panpan1.1		panPan2

IL19
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	6,000,994 - 6,006,959 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	6,000,907 - 6,006,870 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	5,565,084 - 5,571,055 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	5,690,270 - 5,696,253 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	5,690,393 - 5,696,158 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	5,624,790 - 5,630,761 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	5,725,835 - 5,731,813 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	5,765,463 - 5,771,442 (+)	NCBI		UU_Cfam_GSD_1.0

Il19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	68,524,432 - 68,529,571 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936557	5,765,093 - 5,769,853 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936557	5,765,093 - 5,769,853 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL19
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	67,469,524 - 67,479,813 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	67,469,519 - 67,479,597 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	73,826,995 - 73,836,970 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL19
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	22,514,199 - 22,523,680 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	22,514,559 - 22,520,499 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	23,185,637 - 23,225,958 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il19
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	4,636,374 - 4,641,022 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624807	4,636,357 - 4,641,022 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013502759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013502762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01006704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01006705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000020587 ⟹ ENSCLAP00000020390

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955406	42,376,104 - 42,384,902 (+)	Ensembl

RefSeq Acc Id:

XM_013502759 ⟹ XP_013358213

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955406	42,376,104 - 42,384,902 (+)	NCBI

Sequence:

show sequence

CATAGTGATCGGAAGTTTATTTTTCCGAGAAACTGTGTGTCAAGAGAAAGAGGCATTTCTTAAT
AATGATTAGTCAGATACATAGCAAAGAAGGAGAAGAAGAAGAAGAAGAAAAGAAAATAATTAAG
GAAGTGAAATGTGAAAAAAGGAGAGCAAAATGACTTCCCAAAGGGGGACCCACCCTATAAACTT
TGACAGCATTTCCTCCTAGCCACCTGCATAAAAGTGACCAGCACTTTCCAAATGGCAAAGAGCA
CACAGAGAGAAGACACAGGAGCAGCTGGAAGGATTGCAGTGAGAGGATATGAAGGCACAGGGTG
TTGCCCTCTGGCTCCTGGGTACTGCACTTGTCCTGTGCTCCATGTACACGCATGGGTTCAGGAG
GTGCCTAACTTCTGTGGACATGCATCACCTAGAAGAGTGTTTCCAAGAAATCAAAAGAGCCGTC
CAAACCAAGGACATCTTCCCAAACATCACCATCTTGTCCACAGTGGAGACCCTGAGGAGTGTTA
AGCCCATGGATGTGTGCTGTGTGACCAAGAATCTCCTGGAGTTCTACATGGACCGGGTTTTCAA
GGACCATCAGGAGCTGAAGCCTCAGATCTTGAGAAGAATCAGCAGCATTGCCAACTCTTTCCTC
TACATGCAGAAAACCCTGCAGCAGTGTCAGGTGCAGAGACGGTGTCACTGCAGTGAGGAAGCTA
CCAATGCAACCAGAATGGTGCATGACAACTACGATCAGCTGGAAGTTCCTTCTGCTGCCACTAA
ATCTCTGGGAGAACTCGATGTCTTTCTAGCTTGGATTGAGAAGAATCATCAGGAAACTTCACCT
GCCTGACACCAGGAGCTGATCCAAGGGTGAACACTTCGTGTTTCCTGAGGAGACAGCTGACTTT
GAAGGCAAGAGAGATGGAGAGGTCACTCCATGTTCACTGAAGTGGAGGTCTTTTCAAAGAAACT
GACTTCTCTCCTCCGGAACTGGGGCATTGTAGGGAAAAACCTGAGCCTGAGCAGATCTCACCCT
GCAGCCCAAGTCTCCCAGGCAGGTTTCTGGCTGTCTGATCCCACTTGAAAATAGCCAGATTGTC
TACGGTGATATTTATGATGAAACAGGTCATTTGAAAGCCCTCAGAGCCATCCTGGAAGGAGAGG
GTTGTTTCCCCATTAACTTATTGCAAAGTTGCCTCTCCCACGGCGGTGTTGTGAGCTATGTAGT
CTCCTGTAGTACATATTGTACTGCCTGACACTTCTGAATAAACTCTGCTGTACTTATGAGTGGA
AA

hide sequence

RefSeq Acc Id:

XM_013502762 ⟹ XP_013358216

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955406	42,376,102 - 42,384,902 (+)	NCBI

Sequence:

show sequence

TGCATAGTGATCGGAAGTTTATTTTTCCGAGAAACTGTGTGTCAAGAGAAAGAGGCATTTCTTA
ATAATGATTAGTCAGATACATAGCAAAGAAGGAGAAGAAGAAGAAGAAGAAAAGAAAATAATTA
AGGAAGTGAAATGTGAAAAAAGGAGAGCAAAATGACTTCCCAAAGGGGGACCCACCCTATAAAC
TTTGACAGCATTTCCTCCTAGCCACCTGCATAAAAGTGACCAGCACTTTCCAAATGGCAAAGAG
CACACAGAGAGAAGACACAGGAGCAGCTGGAAGGATTGCAGTGAGAGGATATGAAGGCACAGGG
TGTTGCCCTCTGGCTCCTGGGTACTGCACTTGTCCTGTGCTCCATGTACACGCATGGGTTCAGG
AGGTGCCTAACTTCTGTGGACATGCATCACCTAGAAGAGTGTTTCCAAGAAATCAAAAGAGCCG
TCCAAACCAAGGACATCTTCCCAAACATCACCATCTTGTCCACAGTGGAGACCCTGAGGAGTGT
TAAGCCCATGGATGTGTGCTGTGTGACCAAGAATCTCCTGGAGTTCTACATGGACCGGGTTTTC
AAGGACCATCAGGAGCTGAAGCCTCAGATCTTGAGAAGAATCAGCAGCATTGCCAACTCTTTCC
TCTACATGCAGAAAACCCTGCAGCAGTGTCTGGAAGTTCCTTCTGCTGCCACTAAATCTCTGGG
AGAACTCGATGTCTTTCTAGCTTGGATTGAGAAGAATCATCAGGAAACTTCACCTGCCTGACAC
CAGGAGCTGATCCAAGGGTGAACACTTCGTGTTTCCTGAGGAGACAGCTGACTTTGAAGGCAAG
AGAGATGGAGAGGTCACTCCATGTTCACTGAAGTGGAGGTCTTTTCAAAGAAACTGACTTCTCT
CCTCCGGAACTGGGGCATTGTAGGGAAAAACCTGAGCCTGAGCAGATCTCACCCTGCAGCCCAA
GTCTCCCAGGCAGGTTTCTGGCTGTCTGATCCCACTTGAAAATAGCCAGATTGTCTACGGTGAT
ATTTATGATGAAACAGGTCATTTGAAAGCCCTCAGAGCCATCCTGGAAGGAGAGGGTTGTTTCC
CCATTAACTTATTGCAAAGTTGCCTCTCCCACGGCGGTGTTGTGAGCTATGTAGTCTCCTGTAG
TACATATTGTACTGCCTGACACTTCTGAATAAACTCTGCTGTACTTATGAGTGGAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013358213	(Get FASTA)	NCBI Sequence Viewer
	XP_013358216	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000020390
	ENSCLAP00000020390.1

RefSeq Acc Id:	XP_013358216 ⟸ XM_013502762
- Peptide Label:	isoform X2
- Sequence:	show sequence MKAQGVALWLLGTALVLCSMYTHGFRRCLTSVDMHHLEECFQEIKRAVQTKDIFPNITILSTVE TLRSVKPMDVCCVTKNLLEFYMDRVFKDHQELKPQILRRISSIANSFLYMQKTLQQCLEVPSAA TKSLGELDVFLAWIEKNHQETSPA hide sequence

RefSeq Acc Id:	XP_013358213 ⟸ XM_013502759
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2VTF1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKAQGVALWLLGTALVLCSMYTHGFRRCLTSVDMHHLEECFQEIKRAVQTKDIFPNITILSTVE TLRSVKPMDVCCVTKNLLEFYMDRVFKDHQELKPQILRRISSIANSFLYMQKTLQQCQVQRRCH CSEEATNATRMVHDNYDQLEVPSAATKSLGELDVFLAWIEKNHQETSPA hide sequence

RefSeq Acc Id:

ENSCLAP00000020390 ⟸ ENSCLAT00000020587

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013970	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000020587	ENTREZGENE
	ENSCLAT00000020587.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.10	UniProtKB/TrEMBL
InterPro	4_helix_cytokine-like_core	UniProtKB/TrEMBL
	IL-10/19/20/22/24/26_fam	UniProtKB/TrEMBL
	IL-10_CS	UniProtKB/TrEMBL
	IL-19	UniProtKB/TrEMBL
NCBI Gene	Il19	ENTREZGENE
PANTHER	INTERLEUKIN-19	UniProtKB/TrEMBL
	INTERLEUKIN-19-RELATED	UniProtKB/TrEMBL
Pfam	IL10	UniProtKB/TrEMBL
PRINTS	INTRLEUKIN19	UniProtKB/TrEMBL
PROSITE	INTERLEUKIN_10	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47266	UniProtKB/TrEMBL
UniProt	A0A8C2VTF1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)