Unc5b (unc-5 netrin receptor B) - Rat Genome Database

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Gene: Unc5b (unc-5 netrin receptor B) Chinchilla lanigera
Analyze
Symbol: Unc5b
Name: unc-5 netrin receptor B
RGD ID: 8738883
Description: ENCODES a protein that exhibits netrin receptor activity (ortholog); INVOLVED IN anterior/posterior axon guidance (ortholog); axon guidance (ortholog); negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); Subarachnoid Hemorrhage (ortholog); FOUND IN membrane raft (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: netrin receptor UNC5B; unc-5 homolog B
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543720,120,946 - 20,199,877 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543720,120,996 - 20,199,877 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Unc5b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543720,120,946 - 20,199,877 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543720,120,996 - 20,199,877 (-)NCBIChiLan1.0ChiLan1.0
UNC5B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381071,212,570 - 71,302,864 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1071,212,570 - 71,302,864 (+)EnsemblGRCh38hg38GRCh38
GRCh371072,972,327 - 73,062,621 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361072,642,353 - 72,729,722 (+)NCBINCBI36Build 36hg18NCBI36
Build 341072,642,354 - 72,729,714NCBI
Celera1066,254,788 - 66,343,547 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1066,966,129 - 67,056,670 (+)NCBIHuRef
CHM1_11073,254,992 - 73,345,299 (+)NCBICHM1_1
T2T-CHM13v2.01072,082,200 - 72,172,412 (+)NCBIT2T-CHM13v2.0
Unc5b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391060,598,373 - 60,667,360 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1060,598,372 - 60,667,360 (-)EnsemblGRCm39 Ensembl
GRCm381060,762,594 - 60,831,581 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1060,762,593 - 60,831,581 (-)EnsemblGRCm38mm10GRCm38
MGSCv371060,225,343 - 60,294,329 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361060,157,952 - 60,226,938 (-)NCBIMGSCv36mm8
Celera1061,863,405 - 61,932,538 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1031.52NCBI
Unc5b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82029,240,639 - 29,307,270 (-)NCBIGRCr8
mRatBN7.22028,697,726 - 28,764,474 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2028,697,726 - 28,764,537 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2029,713,216 - 29,779,955 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02029,099,533 - 29,166,268 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02029,842,007 - 29,908,740 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02030,339,680 - 30,406,593 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2030,339,673 - 30,406,295 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02032,148,315 - 32,215,391 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42028,095,243 - 28,162,204 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12028,109,042 - 28,176,004 (-)NCBI
Celera2030,138,282 - 30,201,182 (-)NCBICelera
Cytogenetic Map20q11NCBI
UNC5B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2883,362,648 - 83,453,001 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11083,367,973 - 83,458,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01067,682,415 - 67,772,760 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11070,207,998 - 70,298,038 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1070,207,998 - 70,298,038 (+)Ensemblpanpan1.1panPan2
UNC5B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1422,003,131 - 22,084,107 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl422,003,131 - 22,081,744 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha422,139,026 - 22,219,691 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0422,280,582 - 22,358,557 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl422,280,284 - 22,357,950 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1422,178,248 - 22,258,859 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0422,383,898 - 22,464,744 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0422,736,647 - 22,817,352 (+)NCBIUU_Cfam_GSD_1.0
Unc5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721358,980,118 - 59,055,010 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365217,470,663 - 7,547,793 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365217,472,788 - 7,547,408 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC5B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1474,120,050 - 74,205,263 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11474,120,055 - 74,208,055 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21480,011,267 - 80,098,887 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UNC5B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1959,995,997 - 60,086,663 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604820,718,376 - 20,809,131 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc5b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247545,204,855 - 5,282,170 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247545,204,875 - 5,280,479 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000017596   ⟹   ENSCLAP00000017426
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543720,120,946 - 20,199,877 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000017597   ⟹   ENSCLAP00000017427
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543720,120,946 - 20,199,877 (-)Ensembl
RefSeq Acc Id: XM_005390040   ⟹   XP_005390097
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543720,120,996 - 20,199,877 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005390097 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000017426
  ENSCLAP00000017426.1
  ENSCLAP00000017427.1
Reference Protein Sequences
RefSeq Acc Id: XP_005390097   ⟸   XM_005390040
- UniProtKB: A0A8C2VLI5 (UniProtKB/TrEMBL),   A0A8C2VLG8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000017426   ⟸   ENSCLAT00000017596
RefSeq Acc Id: ENSCLAP00000017427   ⟸   ENSCLAT00000017597
Protein Domains
Ig-like   ZU5


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011971 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000017596 ENTREZGENE
  ENSCLAT00000017596.1 UniProtKB/TrEMBL
  ENSCLAT00000017597.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/TrEMBL
  2.20.100.10 UniProtKB/TrEMBL
  2.60.220.30 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/TrEMBL
  Death_domain UniProtKB/TrEMBL
  Death_UNC5B UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
  UNC5 UniProtKB/TrEMBL
  UPA UniProtKB/TrEMBL
  ZU5_dom UniProtKB/TrEMBL
NCBI Gene Unc5b ENTREZGENE
PANTHER NETRIN RECEPTOR UNC5B UniProtKB/TrEMBL
  PTHR12582 UniProtKB/TrEMBL
Pfam Death UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
  UPA UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
PRINTS TSP1REPEAT UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
SMART DEATH UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
  ZU5 UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A8C2VLG8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VLI5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Unc5b  unc-5 netrin receptor B    unc-5 homolog B (C. elegans)  Symbol and/or name change 5135510 APPROVED