Nhs (NHS actin remodeling regulator) - Rat Genome Database

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Gene: Nhs (NHS actin remodeling regulator) Chinchilla lanigera
Analyze
Symbol: Nhs
Name: NHS actin remodeling regulator
RGD ID: 8734796
Description: INVOLVED IN cell differentiation (ortholog); lens development in camera-type eye (ortholog); ASSOCIATED WITH autistic disorder (ortholog); cataract (ortholog); cataract 40 (ortholog); FOUND IN cell junction (ortholog); Golgi apparatus (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Nance-Horan syndrome (congenital cataracts and dental anomalies)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955519599,682 - 918,762 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955519596,216 - 919,352 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nhs
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955519599,682 - 918,762 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955519596,216 - 919,352 (-)NCBIChiLan1.0ChiLan1.0
NHS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X17,375,200 - 17,735,994 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX17,375,200 - 17,735,994 (+)EnsemblGRCh38hg38GRCh38
GRCh37X17,393,323 - 17,754,114 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X17,303,464 - 17,664,035 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X17,153,199 - 17,513,768NCBI
CeleraX21,515,624 - 21,873,432 (+)NCBICelera
Cytogenetic MapXp22.2-p22.13NCBI
HuRefX15,153,213 - 15,512,673 (+)NCBIHuRef
CHM1_1X17,424,184 - 17,784,494 (+)NCBICHM1_1
T2T-CHM13v2.0X16,957,799 - 17,318,610 (+)NCBIT2T-CHM13v2.0
Nhs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X160,616,286 - 160,942,437 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX160,616,292 - 160,942,726 (-)EnsemblGRCm39 Ensembl
GRCm38X161,833,290 - 162,159,441 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX161,833,296 - 162,159,730 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X158,274,200 - 158,597,722 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X157,180,373 - 157,503,895 (-)NCBIMGSCv36mm8
CeleraX145,069,096 - 145,393,381 (-)NCBICelera
Cytogenetic MapXF4NCBI
cM MapX74.17NCBI
Nhs
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X36,185,067 - 36,524,711 (+)NCBIGRCr8
mRatBN7.2X32,553,300 - 32,892,961 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX32,552,026 - 32,889,992 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX33,582,578 - 33,916,873 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X37,022,712 - 37,359,427 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X33,207,548 - 33,541,837 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X34,312,102 - 34,675,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX34,623,405 - 34,673,742 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X34,656,286 - 35,018,650 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X53,321,827 - 53,720,326 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX32,845,030 - 33,180,545 (+)NCBICelera
Cytogenetic MapXq14NCBI
NHS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X19,163,540 - 19,534,073 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X19,166,931 - 19,538,278 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X9,988,584 - 10,359,110 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X17,357,898 - 17,728,178 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX17,358,416 - 17,728,178 (+)Ensemblpanpan1.1panPan2
NHS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X13,487,919 - 13,834,869 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX13,488,515 - 13,831,386 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX13,339,834 - 13,686,761 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X13,451,227 - 13,798,368 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX13,451,793 - 13,795,287 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X13,518,311 - 13,864,906 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X13,504,402 - 13,851,231 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X13,573,553 - 13,920,854 (+)NCBIUU_Cfam_GSD_1.0
Nhs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X6,887,249 - 6,971,110 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364706,919,623 - 6,971,125 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364706,632,724 - 6,967,878 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NHS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX14,097,006 - 14,206,568 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X13,854,950 - 14,209,085 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X14,951,338 - 15,302,337 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NHS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X15,803,386 - 16,183,809 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX16,168,609 - 16,183,787 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605617,683,202 - 18,052,952 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nhs
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248292,186,048 - 2,517,372 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248292,185,410 - 2,520,869 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000002317   ⟹   ENSCLAP00000002269
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955519599,682 - 918,762 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000002318   ⟹   ENSCLAP00000002270
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955519599,682 - 918,762 (-)Ensembl
RefSeq Acc Id: XM_005409131   ⟹   XP_005409188
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955519596,216 - 919,352 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005409133   ⟹   XP_005409190
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955519596,216 - 672,175 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005409134   ⟹   XP_005409191
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955519596,216 - 687,405 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005409188 (Get FASTA)   NCBI Sequence Viewer  
  XP_005409190 (Get FASTA)   NCBI Sequence Viewer  
  XP_005409191 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000002269
  ENSCLAP00000002269.1
  ENSCLAP00000002270.1
Reference Protein Sequences
RefSeq Acc Id: XP_005409188   ⟸   XM_005409131
- Peptide Label: isoform X1
- UniProtKB: A0A8C2ULB7 (UniProtKB/TrEMBL),   A0A8C2UP52 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005409191   ⟸   XM_005409134
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UP52 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005409190   ⟸   XM_005409133
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UP52 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000002269   ⟸   ENSCLAT00000002317
RefSeq Acc Id: ENSCLAP00000002270   ⟸   ENSCLAT00000002318


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001640 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000002317 ENTREZGENE
  ENSCLAT00000002317.1 UniProtKB/TrEMBL
  ENSCLAT00000002318.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.340 UniProtKB/TrEMBL
InterPro NHS_fam UniProtKB/TrEMBL
NCBI Gene Nhs ENTREZGENE
PANTHER NANCE-HORAN SYNDROME PROTEIN UniProtKB/TrEMBL
  NANCE-HORAN SYNDROME PROTEIN UniProtKB/TrEMBL
Pfam NHS UniProtKB/TrEMBL
UniProt A0A8C2ULB7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UP52 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Nhs  NHS actin remodeling regulator    Nance-Horan syndrome (congenital cataracts and dental anomalies)  Symbol and/or name change 5135510 APPROVED