Mief1 (mitochondrial elongation factor 1) - Rat Genome Database

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Gene: Mief1 (mitochondrial elongation factor 1) Chinchilla lanigera
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Symbol: Mief1
Name: mitochondrial elongation factor 1
RGD ID: 8734782
Description: ENCODES a protein that exhibits ADP binding (ortholog); GDP binding (ortholog); identical protein binding (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); mitochondrial fission (ortholog); mitochondrial fusion (ortholog); PARTICIPATES IN mitochondria fission pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); genetic disease (ortholog); Optic Atrophy 14 (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mitochondrial dynamics protein MID51; Smcr7l; Smith-Magenis syndrome chromosome region, candidate 7-like
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,387,399 - 25,401,484 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,387,399 - 25,401,484 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mief1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,387,399 - 25,401,484 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,387,399 - 25,401,484 (+)NCBIChiLan1.0ChiLan1.0
MIEF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,500,100 - 39,518,132 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,499,432 - 39,518,132 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,896,105 - 39,914,137 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,228,230 - 38,244,083 (+)NCBINCBI36Build 36hg18NCBI36
Celera2223,700,340 - 23,716,193 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,862,794 - 22,878,726 (+)NCBIHuRef
CHM1_12239,857,023 - 39,872,876 (+)NCBICHM1_1
T2T-CHM13v2.02239,970,729 - 39,988,762 (+)NCBIT2T-CHM13v2.0
Mief1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,118,284 - 80,137,572 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,118,219 - 80,137,572 (+)EnsemblGRCm39 Ensembl
GRCm381580,233,964 - 80,253,372 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,234,018 - 80,253,371 (+)EnsemblGRCm38mm10GRCm38
MGSCv371580,064,510 - 80,083,801 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,061,375 - 80,079,979 (+)NCBIMGSCv36mm8
Celera1582,351,834 - 82,370,715 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
Mief1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,666,918 - 113,679,550 (+)NCBIGRCr8
mRatBN7.27111,786,630 - 111,802,220 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,786,709 - 111,802,220 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,541,220 - 113,553,854 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,764,757 - 115,777,391 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,734,118 - 115,746,753 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,462,962 - 121,478,545 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,462,966 - 121,478,546 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,451,086 - 121,466,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,526,138 - 118,531,814 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,560,367 - 118,566,044 (+)NCBI
Celera7108,114,129 - 108,126,760 (+)NCBICelera
Cytogenetic Map7q34NCBI
MIEF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22349,349,448 - 49,369,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,040,839 - 52,056,693 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,408,502 - 20,424,327 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12238,228,876 - 38,244,774 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2238,228,939 - 38,244,774 (+)Ensemblpanpan1.1panPan2
MIEF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,534,231 - 25,548,565 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,536,288 - 25,546,369 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,470,090 - 25,484,439 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,285,972 - 26,300,295 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,285,988 - 26,300,166 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11026,000,543 - 26,014,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,320,077 - 26,334,405 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,495,583 - 26,510,147 (-)NCBIUU_Cfam_GSD_1.0
Mief1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049459,108,151 - 9,120,757 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364922,117,790 - 2,131,220 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364922,118,565 - 2,132,181 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIEF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.158,748,171 - 8,762,087 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.256,049,362 - 6,061,727 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIEF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,072,217 - 22,087,577 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,081,838 - 22,085,527 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045103,564,685 - 103,578,229 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mief1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247528,830,485 - 8,841,210 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247528,827,202 - 8,841,278 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000024283   ⟹   ENSCLAP00000024052
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541325,387,399 - 25,401,484 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000024284   ⟹   ENSCLAP00000024053
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495541325,389,205 - 25,400,156 (+)Ensembl
RefSeq Acc Id: XM_005379296   ⟹   XP_005379353
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,387,399 - 25,401,484 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005379297   ⟹   XP_005379354
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,387,399 - 25,401,484 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005379298   ⟹   XP_005379355
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,387,399 - 25,401,484 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013511528   ⟹   XP_013366982
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495541325,387,399 - 25,401,484 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005379355   ⟸   XM_005379298
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W235 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005379354   ⟸   XM_005379297
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W235 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005379353   ⟸   XM_005379296
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W235 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013366982   ⟸   XM_013511528
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000024053   ⟸   ENSCLAT00000024284
RefSeq Acc Id: ENSCLAP00000024052   ⟸   ENSCLAT00000024283

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016517 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000024283 ENTREZGENE
  ENSCLAT00000024283.1 UniProtKB/TrEMBL
  ENSCLAT00000024284 ENTREZGENE
  ENSCLAT00000024284.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1410.40 UniProtKB/TrEMBL
  3.30.460.90 UniProtKB/TrEMBL
InterPro Mab-21_dom UniProtKB/TrEMBL
  Mab-21_HhH/H2TH-like UniProtKB/TrEMBL
  MID49/MID51 UniProtKB/TrEMBL
  MID51-like_C UniProtKB/TrEMBL
NCBI Gene Smcr7l ENTREZGENE
PANTHER MITOCHONDRIAL DYNAMICS PROTEIN MID51 UniProtKB/TrEMBL
  PTHR16451 UniProtKB/TrEMBL
Pfam Mab-21_C UniProtKB/TrEMBL
  MID51-like_C UniProtKB/TrEMBL
SMART Mab-21 UniProtKB/TrEMBL
UniProt A0A8C2W235 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-25 Mief1  mitochondrial elongation factor 1  Smcr7l  Smith-Magenis syndrome chromosome region, candidate 7-like  Symbol and/or name change 5135510 APPROVED