Siah3 (siah E3 ubiquitin protein ligase family member 3) - Rat Genome Database

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Gene: Siah3 (siah E3 ubiquitin protein ligase family member 3) Chinchilla lanigera
Analyze
Symbol: Siah3
Name: siah E3 ubiquitin protein ligase family member 3
RGD ID: 8733104
Description: INVOLVED IN negative regulation of protein targeting to mitochondrion (ortholog); regulation of protein stability (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: seven in absentia homolog 3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555183,472,425 - 3,539,115 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555183,473,120 - 3,539,086 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Siah3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555183,472,425 - 3,539,115 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555183,473,120 - 3,539,086 (-)NCBIChiLan1.0ChiLan1.0
SIAH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381345,777,242 - 45,851,753 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1345,777,242 - 45,851,753 (-)EnsemblGRCh38hg38GRCh38
GRCh371346,351,377 - 46,425,888 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361345,252,406 - 45,323,847 (-)NCBINCBI36Build 36hg18NCBI36
Celera1327,409,074 - 27,480,538 (-)NCBICelera
Cytogenetic Map13q14.13NCBI
HuRef1327,151,095 - 27,222,572 (-)NCBIHuRef
CHM1_11346,323,339 - 46,394,823 (-)NCBICHM1_1
T2T-CHM13v2.01344,998,546 - 45,073,093 (-)NCBIT2T-CHM13v2.0
Siah3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391475,693,372 - 75,767,148 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1475,693,422 - 75,767,148 (+)EnsemblGRCm39 Ensembl
GRCm381475,455,982 - 75,526,141 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,455,982 - 75,529,708 (+)EnsemblGRCm38mm10GRCm38
MGSCv371475,855,789 - 75,925,948 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361474,190,132 - 74,260,462 (+)NCBIMGSCv36mm8
Celera1472,957,859 - 73,027,877 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1440.08NCBI
Siah3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81557,180,245 - 57,247,608 (+)NCBIGRCr8
mRatBN7.21550,770,839 - 50,838,213 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1550,770,871 - 50,834,487 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1554,920,651 - 54,983,939 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01556,038,968 - 56,102,263 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01552,863,924 - 52,928,634 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,505,449 - 57,568,743 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,505,449 - 57,568,743 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01561,215,305 - 61,278,376 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41556,320,672 - 56,387,549 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1550,401,567 - 50,465,060 (+)NCBICelera
Cytogenetic Map15q11NCBI
SIAH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21445,539,882 - 45,612,512 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11336,593,953 - 36,666,560 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01327,180,382 - 27,255,005 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SIAH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1225,320,083 - 5,390,389 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl225,320,249 - 5,386,508 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,309,191 - 5,379,473 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0225,438,371 - 5,508,337 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl225,438,394 - 5,510,519 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1225,219,846 - 5,290,132 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0225,283,539 - 5,353,477 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0225,288,339 - 5,358,617 (+)NCBIUU_Cfam_GSD_1.0
Siah3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945155,915,563 - 155,984,592 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936857339,615 - 406,806 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936857341,879 - 406,806 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIAH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,501,492 - 21,562,077 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11121,500,605 - 21,562,301 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21122,075,723 - 22,078,885 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SIAH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1323,840,947 - 23,909,954 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl323,841,195 - 23,908,631 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605720,108,328 - 20,176,080 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Siah3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247489,136,650 - 9,231,109 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247489,136,665 - 9,234,392 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000000646   ⟹   ENSCLAP00000000613
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555183,472,425 - 3,539,115 (-)Ensembl
RefSeq Acc Id: XM_005409091   ⟹   XP_005409148
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555183,473,120 - 3,539,086 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013506955   ⟹   XP_013362409
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555183,473,120 - 3,477,494 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001231838
Type: NON-CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555183,474,017 - 3,477,494 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005409148 (Get FASTA)   NCBI Sequence Viewer  
  XP_013362409 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000000613
  ENSCLAP00000000613.1
RefSeq Acc Id: XP_005409148   ⟸   XM_005409091
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UHH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013362409   ⟸   XM_013506955
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSCLAP00000000613   ⟸   ENSCLAT00000000646

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000493 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000000646 ENTREZGENE
  ENSCLAT00000000646.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro 7-in-absentia-prot_TRAF-dom UniProtKB/TrEMBL
  SINA-like_animal UniProtKB/TrEMBL
  TRAF-like UniProtKB/TrEMBL
NCBI Gene Siah3 ENTREZGENE
PANTHER PTHR45877 UniProtKB/TrEMBL
  SEVEN IN ABSENTIA HOMOLOG 3 UniProtKB/TrEMBL
Pfam Sina UniProtKB/TrEMBL
Superfamily-SCOP TRAF domain-like UniProtKB/TrEMBL
UniProt A0A8C2UHH8 ENTREZGENE, UniProtKB/TrEMBL