Mid2 (midline 2) - Rat Genome Database

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Gene: Mid2 (midline 2) Chinchilla lanigera
Analyze
Symbol: Mid2
Name: midline 2
RGD ID: 8730998
Description: ENCODES a protein that exhibits enzyme binding (ortholog); identical protein binding (ortholog); microtubule binding (ortholog); INVOLVED IN innate immune response (ortholog); negative regulation of viral entry into host cell (ortholog); negative regulation of viral transcription (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Charcot-Marie-Tooth disease type X (ortholog); esophageal atresia (ortholog); FOUND IN microtubule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: probable E3 ubiquitin-protein ligase MID2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554907,973,211 - 8,088,427 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554907,977,771 - 8,168,912 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Mid2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554907,973,211 - 8,088,427 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554907,977,771 - 8,168,912 (-)NCBIChiLan1.0ChiLan1.0
MID2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X107,825,735 - 107,931,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX107,825,755 - 107,931,637 (+)EnsemblGRCh38hg38GRCh38
GRCh37X107,068,965 - 107,174,867 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X106,956,116 - 107,057,077 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX107,540,045 - 107,645,826 (+)NCBICelera
Cytogenetic MapXq22.3NCBI
HuRefX96,692,632 - 96,797,758 (+)NCBIHuRef
CHM1_1X106,979,937 - 107,085,716 (+)NCBICHM1_1
T2T-CHM13v2.0X106,262,471 - 106,368,728 (+)NCBIT2T-CHM13v2.0
Mid2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X139,565,326 - 139,668,464 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX139,565,348 - 139,668,464 (+)EnsemblGRCm39 Ensembl
GRCm38X140,664,304 - 140,767,715 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX140,664,599 - 140,767,715 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X137,212,567 - 137,302,254 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X136,011,320 - 136,114,080 (+)NCBIMGSCv36mm8
CeleraX123,937,263 - 124,027,053 (+)NCBICelera
Cytogenetic MapXF1NCBI
cM MapX61.35NCBI
Mid2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X109,143,057 - 109,245,257 (+)NCBIGRCr8
mRatBN7.2X104,354,692 - 104,456,757 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX104,355,316 - 104,453,473 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX106,484,643 - 106,582,790 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X109,983,989 - 110,082,138 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X107,531,877 - 107,629,899 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X112,019,897 - 112,121,980 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX112,020,646 - 112,121,943 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0352,479,569 - 52,581,663 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X128,496,689 - 128,595,233 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera343,484,990 - 43,583,167 (-)NCBICelera
Cytogenetic MapXq33NCBI
MID2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X107,301,285 - 107,405,554 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X107,304,702 - 107,413,484 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X96,917,731 - 97,026,545 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X107,290,776 - 107,393,162 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX107,290,776 - 107,393,162 (+)Ensemblpanpan1.1panPan2
MID2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X81,267,037 - 81,467,613 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX81,296,249 - 81,463,210 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX67,387,281 - 67,588,271 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X82,914,364 - 83,116,618 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX82,942,999 - 83,112,209 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X80,374,592 - 80,575,813 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X82,086,451 - 82,288,627 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X81,878,438 - 82,081,198 (+)NCBIUU_Cfam_GSD_1.0
Mid2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X80,731,399 - 80,828,234 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364996,829,729 - 6,926,571 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364996,833,328 - 6,926,531 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MID2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX88,294,067 - 88,393,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X88,294,032 - 88,394,885 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X102,730,773 - 102,831,117 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MID2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X95,664,705 - 95,760,256 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX95,665,380 - 95,764,762 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606520,771,575 - 20,871,556 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mid2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248038,536,953 - 8,650,805 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248038,536,946 - 8,650,775 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000001741   ⟹   ENSCLAP00000001698
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554907,973,211 - 8,088,427 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000001742   ⟹   ENSCLAP00000001699
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554907,977,771 - 8,087,308 (-)Ensembl
RefSeq Acc Id: XM_005404684   ⟹   XP_005404741
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554907,977,771 - 8,168,912 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005404685   ⟹   XP_005404742
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554907,977,771 - 8,083,956 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005404688   ⟹   XP_005404745
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554907,977,771 - 8,087,308 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005404690   ⟹   XP_005404747
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554907,977,771 - 8,087,852 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013504523   ⟹   XP_013359977
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554907,977,771 - 8,074,820 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005404741   ⟸   XM_005404684
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UJ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404747   ⟸   XM_005404690
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UJ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404745   ⟸   XM_005404688
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UJ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005404742   ⟸   XM_005404685
- Peptide Label: isoform X1
- UniProtKB: A0A8C2UJ56 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013359977   ⟸   XM_013504523
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UJ59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000001698   ⟸   ENSCLAT00000001741
RefSeq Acc Id: ENSCLAP00000001699   ⟸   ENSCLAT00000001742

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000001268 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000001741 ENTREZGENE
  ENSCLAT00000001741.1 UniProtKB/TrEMBL
  ENSCLAT00000001742 ENTREZGENE
  ENSCLAT00000001742.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
  4.10.830.40 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro B30.2/SPRY UniProtKB/TrEMBL
  B30.2/SPRY_sf UniProtKB/TrEMBL
  Bbox_C UniProtKB/TrEMBL
  Butyrophylin_SPRY UniProtKB/TrEMBL
  ConA-like_dom_sf UniProtKB/TrEMBL
  COS_domain UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  MID2_Bbox1_Zfn UniProtKB/TrEMBL
  MID2_Bbox2_Zfn UniProtKB/TrEMBL
  Midline-1_COS UniProtKB/TrEMBL
  SPRY/PRY_TRIM1 UniProtKB/TrEMBL
  SPRY_dom UniProtKB/TrEMBL
  Znf-RING_euk UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Mid2 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED UniProtKB/TrEMBL
  PTHR24099:SF12 UniProtKB/TrEMBL
Pfam COS UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
  zf-RING_UBOX UniProtKB/TrEMBL
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  COS UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART BBC UniProtKB/TrEMBL
  BBOX UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  RING/U-box UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
UniProt A0A8C2UJ56 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UJ59 ENTREZGENE, UniProtKB/TrEMBL