Tmed5 (transmembrane p24 trafficking protein 5)

Gene: Tmed5 (transmembrane p24 trafficking protein 5) Chinchilla lanigera

Analyze

Symbol:

Tmed5

Name:

transmembrane p24 trafficking protein 5

RGD ID:

8726793

Description:

INVOLVED IN Golgi ribbon formation (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cis-Golgi network (ortholog); endoplasmic reticulum exit site (ortholog); endoplasmic reticulum-Golgi intermediate compartment (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

transmembrane emp24 domain-containing protein 5; transmembrane emp24 protein transport domain containing 5

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	1,436,628 - 1,456,970 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	1,436,628 - 1,456,970 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Golgi ribbon formation (ISO)

Cellular Component

cis-Golgi network (ISO)

endoplasmic reticulum exit site (ISO)

endoplasmic reticulum-Golgi intermediate compartment (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Tmed5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	1,436,628 - 1,456,970 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	1,436,628 - 1,456,970 (+)	NCBI	ChiLan1.0	ChiLan1.0

TMED5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	93,149,742 - 93,180,413 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	93,149,742 - 93,180,516 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	93,615,299 - 93,645,970 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	93,389,999 - 93,418,834 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	93,329,427 - 93,358,267	NCBI
Celera	1	91,869,455 - 91,900,413 (-)	NCBI		Celera
Cytogenetic Map	1	p22.1	NCBI
HuRef	1	91,736,849 - 91,767,806 (-)	NCBI		HuRef
CHM1_1	1	93,730,202 - 93,761,150 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	92,995,327 - 93,026,003 (-)	NCBI		T2T-CHM13v2.0

Tmed5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	108,269,422 - 108,280,486 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	108,254,232 - 108,280,486 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	108,121,556 - 108,132,620 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	108,106,366 - 108,132,620 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	108,550,666 - 108,561,610 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	108,361,949 - 108,372,893 (-)	NCBI		MGSCv36	mm8
Celera	5	105,239,859 - 105,250,741 (-)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	52.49	NCBI

Tmed5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	1,752,857 - 1,763,990 (+)	NCBI		GRCr8
mRatBN7.2	14	1,607,895 - 1,619,028 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	1,607,819 - 1,628,426 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	1,486,848 - 1,497,987 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	2,788,621 - 2,799,760 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	1,485,296 - 1,496,437 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	2,613,318 - 2,624,773 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	2,613,406 - 2,633,950 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	2,612,362 - 2,623,817 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	2,155,594 - 2,167,280 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	2,155,593 - 2,167,271 (+)	NCBI
Celera	14	1,628,691 - 1,639,884 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

TMED5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	133,835,694 - 133,864,516 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	132,990,585 - 133,019,411 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	95,821,324 - 95,850,099 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	94,552,590 - 94,582,875 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	94,552,590 - 94,582,875 (-)	Ensembl	panpan1.1		panPan2

TMED5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	55,917,842 - 55,934,880 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	55,918,077 - 55,932,169 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	58,618,896 - 58,635,690 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	56,293,071 - 56,309,877 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	56,291,987 - 56,309,868 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	55,973,295 - 55,990,051 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	55,951,620 - 55,968,403 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	56,410,717 - 56,427,517 (+)	NCBI		UU_Cfam_GSD_1.0

Tmed5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	102,889,539 - 102,909,871 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936537	6,038,207 - 6,058,437 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936537	6,038,109 - 6,058,434 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMED5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	124,009,816 - 124,030,773 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	124,009,825 - 124,027,445 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	135,564,674 - 135,581,598 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMED5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	40,074,505 - 40,102,773 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	40,074,545 - 40,099,963 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	77,924,333 - 77,952,991 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmed5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	4,508,777 - 4,535,416 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624742	4,508,988 - 4,558,909 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005385018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005385019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01023434	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGCD01023435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDF01193843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000010283 ⟹ ENSCLAP00000010153

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955423	1,436,628 - 1,456,970 (+)	Ensembl

RefSeq Acc Id:

XM_005385018 ⟹ XP_005385075

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955423	1,436,628 - 1,456,970 (+)	NCBI

Sequence:

show sequence

CCCTGCCGCGAGGAGTGCAGGGAGGAAGAGCGGAGCGGCGGCGCCGGCGTCCCATCTCGCACGC
GGCTTTCCGCCCGATTTCGCCCCGGCAGGGATGGGCGACACGATCTGGCTGCCCTTCCCCTTGC
TCCTCCTGGTCGCTTTGCGGCTGCCCGGGACGGCCGGCTTCACGCCTTCCTTAGACAGCGACTT
TACCTTTACCCTTCCGGCCGGCCAGAAGGAGTGTTTCTACCAGCCCATGCCGCTGAAGGCCTCG
CTGGAGATCGAGTACCAAGTCTTAGATGGAGCAGGATTAGATATTGATTTCCATCTTGCCTCTC
CAGAAGGCAAAACTTTAGTTTTTGAACAAAGAAAATCAGATGGAGTTCACACTGTAGAAACTGA
AGTTGGTGATTACATGTTCTGCTTTGACAATACATTCAGCACCATTTCTGAGAAAGTAATTTTC
TTTGAATTAATCCTGGATAATATGGGAGAAGAGGCACAAGAACAAGAAGACTGGAAGAAATATA
TTACTGGTACAGATGTGTTGGAGATGAAACTCGAAGACATCCTGGAATCCATCAACAGCATCAA
GTCCAGAGTAAGCAAAAGTGGTCATATACAAACTCTGCTCAGAGCATTTGAAGCCCGTGATCGA
AACATACAAGAAAGCAACTTTGATAGAGTCAATTTCTGGTCTATGGTTAACTTAGTTGTCATGG
TGGTAGTCTCAGCTATTCAAGTTTATATGCTGAAGAGTCTATTTGAAGATAAAAGAAAAAGTAG
AACTTAAAACTCAACTACTTAACAAAATTGGAAAAAAGTGGGGTCAGAAAAGTGCAGTTGTTAC
CATTAATAGTCAAGACCATTAGTAGTCTTTTCAAAACGTTTGCAGACATTCTCAATAAGTGTAA
AATAAGTATAATTTTAATGTGAAAGTCTTCGTTTTCTGTGCAATCTACTTCACTCATCCAGTTA
CACTTAAGTGTGTAACTGGAATATTTTACATAAGTGTAAGTTTAATTGAAATTCTTACTAATAA
CTGCATTTTTCTAAGTTTTAAAATTTTTACACGCAAAAAAAAAAAAAAAAAAGAAATCAGCCAA
TTTCTAGGGATAGGGATA

hide sequence

RefSeq Acc Id:

XM_005385019 ⟹ XP_005385076

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955423	1,436,628 - 1,456,589 (+)	NCBI

Sequence:

show sequence

CCCTGCCGCGAGGAGTGCAGGGAGGAAGAGCGGAGCGGCGGCGCCGGCGTCCCATCTCGCACGC
GGCTTTCCGCCCGATTTCGCCCCGGCAGGGATGGGCGACACGATCTGGCTGCCCTTCCCCTTGC
TCCTCCTGGTCGCTTTGCGGCTGCCCGGGACGGCCGGCTTCACGCCTTCCTTAGACAGCGACTT
TACCTTTACCCTTCCGGCCGGCCAGAAGGAGTGTTTCTACCAGCCCATGCCGCTGAAGGCCTCG
CTGGAGATCGAGTACCAAGTCTTAGATGGAGCAGGATTAGATATTGATTTCCATCTTGCCTCTC
CAGAAGGCAAAACTTTAGTTTTTGAACAAAGAAAATCAGATGGAGTTCACACTGTAGAAACTGA
AGTTGGTGATTACATGTTCTGCTTTGACAATACATTCAGCACCATTTCTGAGAAAGTAATTTTC
TTTGAATTAATCCTGGATAATATGGGAGAAGAGGCACAAGAACAAGAAGACTGGAAGAAATATA
TTACTGGTACAGATGTGTTGGAGATGAAACTCGAAGACATCCTGGTTATAAAATTATTTTATTT
ATCTCCAGGAATCCATCAACAGCATCAAGTCCAGAGTAAGCAAAAGTGGTCATATACAAACTCT
GCTCAGAGCATTTGAAGCCCGTGATCGAAACATACAAGAAAGCAACTTTGATAGAGTCAATTTC
TGGTCTATGGTTAACTTAGTTGTCATGGTGGTAGTCTCAGCTATTCAAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005385075	(Get FASTA)	NCBI Sequence Viewer
	XP_005385076	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000010153
	ENSCLAP00000010153.1

RefSeq Acc Id:	XP_005385075 ⟸ XM_005385018
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2YMS7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGDTIWLPFPLLLLVALRLPGTAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDG AGLDIDFHLASPEGKTLVFEQRKSDGVHTVETEVGDYMFCFDNTFSTISEKVIFFELILDNMGE EAQEQEDWKKYITGTDVLEMKLEDILESINSIKSRVSKSGHIQTLLRAFEARDRNIQESNFDRV NFWSMVNLVVMVVVSAIQVYMLKSLFEDKRKSRT hide sequence

RefSeq Acc Id:	XP_005385076 ⟸ XM_005385019
- Peptide Label:	isoform X2
- Sequence:	show sequence MGDTIWLPFPLLLLVALRLPGTAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEIEYQVLDG AGLDIDFHLASPEGKTLVFEQRKSDGVHTVETEVGDYMFCFDNTFSTISEKVIFFELILDNMGE EAQEQEDWKKYITGTDVLEMKLEDILVIKLFYLSPGIHQQHQVQSKQKWSYTNSAQSI hide sequence

RefSeq Acc Id:

ENSCLAP00000010153 ⟸ ENSCLAT00000010283

Protein Domains

GOLD

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000007030	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000010283	ENTREZGENE
	ENSCLAT00000010283.1	UniProtKB/TrEMBL
InterPro	Emp24-like	UniProtKB/TrEMBL
	GOLD_dom	UniProtKB/TrEMBL
	GOLD_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Tmed5	ENTREZGENE
PANTHER	PTHR22811	UniProtKB/TrEMBL
	PTHR22811:SF41	UniProtKB/TrEMBL
Pfam	EMP24_GP25L	UniProtKB/TrEMBL
PROSITE	GOLD	UniProtKB/TrEMBL
SMART	EMP24_GP25L	UniProtKB/TrEMBL
Superfamily-SCOP	SSF101576	UniProtKB/TrEMBL
UniProt	A0A8C2YMS7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Tmed5	transmembrane p24 trafficking protein 5		transmembrane emp24 protein transport domain containing 5	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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