Tbc1d10a (TBC1 domain family member 10A) - Rat Genome Database

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Gene: Tbc1d10a (TBC1 domain family member 10A) Chinchilla lanigera
Analyze
Symbol: Tbc1d10a
Name: TBC1 domain family member 10A
RGD ID: 8724092
Description: ENCODES a protein that exhibits PDZ domain binding (ortholog); INVOLVED IN positive regulation of proteolysis (ortholog); regulation of cilium assembly (ortholog); retrograde transport, endosome to Golgi (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TBC1 domain family, member 10A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554554,537,634 - 4,570,949 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554554,537,634 - 4,570,949 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species

Genomics

Comparative Map Data
Tbc1d10a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554554,537,634 - 4,570,949 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554554,537,634 - 4,570,949 (-)NCBIChiLan1.0ChiLan1.0
TBC1D10A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382230,291,990 - 30,326,941 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2230,291,990 - 30,326,947 (-)EnsemblGRCh38hg38GRCh38
GRCh372230,687,979 - 30,722,930 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362229,017,979 - 29,052,894 (-)NCBINCBI36Build 36hg18NCBI36
Celera2214,487,683 - 14,522,588 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2213,649,780 - 13,684,744 (-)NCBIHuRef
CHM1_12230,647,114 - 30,682,078 (-)NCBICHM1_1
T2T-CHM13v2.02230,755,329 - 30,790,284 (-)NCBIT2T-CHM13v2.0
Tbc1d10a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39114,136,852 - 4,167,407 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl114,136,789 - 4,165,505 (+)EnsemblGRCm39 Ensembl
GRCm38114,186,833 - 4,215,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl114,186,789 - 4,215,505 (+)EnsemblGRCm38mm10GRCm38
MGSCv37114,086,836 - 4,115,508 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36114,086,836 - 4,115,508 (+)NCBIMGSCv36mm8
Celera114,683,776 - 4,712,449 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.92NCBI
Tbc1d10a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81483,278,151 - 83,307,178 (+)NCBIGRCr8
mRatBN7.21479,051,822 - 79,083,603 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1479,055,432 - 79,083,600 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1483,496,159 - 83,523,867 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01484,736,238 - 84,763,946 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01481,182,137 - 81,209,845 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01484,417,320 - 84,445,034 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1484,417,320 - 84,445,034 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01485,098,646 - 85,127,054 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41484,810,214 - 84,837,928 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11484,829,295 - 84,857,428 (+)NCBI
Celera1477,966,529 - 77,994,243 (+)NCBICelera
Cytogenetic Map14q21NCBI
TBC1D10A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22340,259,179 - 40,294,040 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12242,957,788 - 42,992,669 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02211,328,159 - 11,363,009 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12229,130,096 - 29,164,838 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2229,130,096 - 29,164,865 (-)Ensemblpanpan1.1panPan2
TBC1D10A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12623,446,251 - 23,478,287 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2623,446,607 - 23,478,317 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2623,317,434 - 23,349,461 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02623,830,218 - 23,862,484 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2623,830,243 - 23,862,523 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12623,531,901 - 23,563,925 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02623,794,735 - 23,826,752 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02623,855,089 - 23,887,117 (-)NCBIUU_Cfam_GSD_1.0
Tbc1d10a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118116,364,225 - 116,378,667 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936904357,634 - 369,652 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936904357,621 - 370,006 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D10A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1447,269,092 - 47,301,753 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11447,269,087 - 47,301,540 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21450,308,036 - 50,332,493 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D10A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11913,172,847 - 13,207,979 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1913,172,845 - 13,207,904 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045112,938,151 - 112,973,593 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d10a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247476,607,448 - 6,643,734 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247476,607,085 - 6,643,745 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000019073   ⟹   ENSCLAP00000018888
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554554,537,634 - 4,570,949 (-)Ensembl
RefSeq Acc Id: XM_005396252   ⟹   XP_005396309
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554554,537,634 - 4,570,949 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005396309 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018888
  ENSCLAP00000018888.1
Reference Protein Sequences
RefSeq Acc Id: XP_005396309   ⟸   XM_005396252
- UniProtKB: A0A8C2VSD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000018888   ⟸   ENSCLAT00000019073
Protein Domains
Rab-GAP TBC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012935 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019073 ENTREZGENE
  ENSCLAT00000019073.1 UniProtKB/TrEMBL
Gene3D-CATH putative rabgap domain of human tbc1 domain family member 14 like domains UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 1 UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
NCBI Gene Tbc1d10a ENTREZGENE
PANTHER RAB GTPASE-ACTIVATING PROTEIN 1-LIKE UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER 10B UniProtKB/TrEMBL
Pfam RabGAP-TBC UniProtKB/TrEMBL
PROSITE TBC_RABGAP UniProtKB/TrEMBL
SMART TBC UniProtKB/TrEMBL
Superfamily-SCOP SSF47923 UniProtKB/TrEMBL
UniProt A0A8C2VSD2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Tbc1d10a  TBC1 domain family member 10A    TBC1 domain family, member 10A  Symbol and/or name change 5135510 APPROVED