Hmbox1 (homeobox containing 1) - Rat Genome Database

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Gene: Hmbox1 (homeobox containing 1) Chinchilla lanigera
Analyze
Symbol: Hmbox1
Name: homeobox containing 1
RGD ID: 8721935
Description: ENCODES a protein that exhibits double-stranded telomeric DNA binding (ortholog); identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of telomere maintenance via telomerase (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN centrosome (ortholog); chromosome, telomeric region (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540351,257,472 - 51,365,835 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hmbox1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540351,257,472 - 51,365,835 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBIChiLan1.0ChiLan1.0
HMBOX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38828,890,116 - 29,053,270 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl828,890,395 - 29,064,764 (+)EnsemblGRCh38hg38GRCh38
GRCh37828,747,912 - 28,910,787 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36828,804,144 - 28,965,351 (+)NCBINCBI36Build 36hg18NCBI36
Celera827,707,732 - 27,869,989 (+)NCBICelera
Cytogenetic Map8p21.1-p12NCBI
HuRef827,293,007 - 27,455,132 (+)NCBIHuRef
CHM1_1828,949,910 - 29,112,203 (+)NCBICHM1_1
T2T-CHM13v2.0829,168,300 - 29,331,436 (+)NCBIT2T-CHM13v2.0
Hmbox1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391465,049,049 - 65,187,354 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1465,049,049 - 65,187,320 (-)EnsemblGRCm39 Ensembl
GRCm381464,811,600 - 64,949,899 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1464,811,600 - 64,949,871 (-)EnsemblGRCm38mm10GRCm38
MGSCv371465,441,055 - 65,568,684 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361463,776,328 - 63,903,957 (-)NCBIMGSCv36mm8
Celera1462,584,174 - 62,711,763 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.79NCBI
Hmbox1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81543,243,503 - 43,376,011 (-)NCBIGRCr8
mRatBN7.21539,067,805 - 39,200,633 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1539,067,804 - 39,200,323 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01548,194,709 - 48,326,310 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1548,199,995 - 48,284,548 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01551,919,925 - 52,073,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41544,182,450 - 44,305,484 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11544,197,983 - 44,320,631 (-)NCBI
Celera1538,744,265 - 38,876,101 (-)NCBICelera
Cytogenetic Map15p12NCBI
HMBOX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2747,434,897 - 47,612,451 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1823,147,878 - 23,325,337 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0828,173,256 - 28,350,591 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1825,370,077 - 25,547,208 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl825,446,264 - 25,547,208 (+)Ensemblpanpan1.1panPan2
HMBOX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12528,489,472 - 28,679,322 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2528,489,506 - 28,679,748 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2529,137,090 - 29,327,184 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02528,643,730 - 28,835,028 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2528,643,730 - 28,835,023 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12528,603,599 - 28,794,841 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02528,491,031 - 28,680,245 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02528,653,266 - 28,842,626 (-)NCBIUU_Cfam_GSD_1.0
Hmbox1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049436,844,865 - 7,007,445 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366751,647,143 - 1,735,390 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366751,578,705 - 1,741,283 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMBOX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1412,692,588 - 12,882,558 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11412,692,607 - 12,895,078 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21413,933,447 - 14,137,116 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HMBOX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1826,999,474 - 27,177,244 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl826,999,468 - 27,163,526 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605214,947,485 - 15,131,238 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hmbox1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475823,548,514 - 23,638,713 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475823,472,719 - 23,649,924 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000021601   ⟹   ENSCLAP00000021398
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540351,257,472 - 51,365,403 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000021602   ⟹   ENSCLAP00000021399
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540351,257,472 - 51,363,723 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000021603   ⟹   ENSCLAP00000021400
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540351,285,139 - 51,365,835 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000021604   ⟹   ENSCLAP00000021401
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540351,285,139 - 51,363,525 (+)Ensembl
RefSeq Acc Id: XM_005373783   ⟹   XP_005373840
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005373787   ⟹   XP_005373844
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005373788   ⟹   XP_005373845
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005373789   ⟹   XP_005373846
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005373790   ⟹   XP_005373847
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514363   ⟹   XP_013369817
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540351,199,547 - 51,377,249 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005373845   ⟸   XM_005373788
- Peptide Label: isoform X3
- UniProtKB: A0A8C2VVS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005373840   ⟸   XM_005373783
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VVS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005373846   ⟸   XM_005373789
- Peptide Label: isoform X5
- UniProtKB: A0A8C2VW66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005373847   ⟸   XM_005373790
- Peptide Label: isoform X6
- UniProtKB: A0A8C2VVS7 (UniProtKB/TrEMBL),   A0A8C2VW66 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005373844   ⟸   XM_005373787
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VVS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369817   ⟸   XM_013514363
- Peptide Label: isoform X4
- UniProtKB: A0A8C2VVS5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000021400   ⟸   ENSCLAT00000021603
RefSeq Acc Id: ENSCLAP00000021401   ⟸   ENSCLAT00000021604
RefSeq Acc Id: ENSCLAP00000021399   ⟸   ENSCLAT00000021602
RefSeq Acc Id: ENSCLAP00000021398   ⟸   ENSCLAT00000021601
Protein Domains
HNF-p1   Homeobox   POU-specific atypical


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014654 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000021601 ENTREZGENE
  ENSCLAT00000021601.1 UniProtKB/TrEMBL
  ENSCLAT00000021602 ENTREZGENE
  ENSCLAT00000021602.1 UniProtKB/TrEMBL
  ENSCLAT00000021603.1 UniProtKB/TrEMBL
  ENSCLAT00000021604 ENTREZGENE
  ENSCLAT00000021604.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.260.40 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Cro/C1-type_HTH UniProtKB/TrEMBL
  HMBOX1 UniProtKB/TrEMBL
  HNF-1_N UniProtKB/TrEMBL
  HNF-1_POU UniProtKB/TrEMBL
  HNF_P1 UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Lambda_DNA-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene Hmbox1 ENTREZGENE
PANTHER HOMEOBOX-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR14618 UniProtKB/TrEMBL
Pfam HNF-1_N UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
PROSITE HNF_P1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  POU_4 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF47413 UniProtKB/TrEMBL
UniProt A0A8C2VVS5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VVS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VW66 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2YT52_CHILA UniProtKB/TrEMBL